Effects of the AT1 receptor blocker losartan and the calcium channel blocker benidipine on the accumulation of lipids in the kidney of a rat model of metabolic syndrome

Hypertension Research

Volumn 33, Issue 3, 2010, Pages 263-268

  Ishizaka, Nobukazu ^a   Hongo, Makiko ^a   Matsuzaki, Gen ^a   Furuta, Kyoko ^a   Saito, Kan ^a   Sakurai, Ryota ^a   Sakamoto, Aiko ^a   Koike, Kazuhiko ^a   Nagai, Ryozo ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Calcium channel blocker; Diabetes; Kidney; Lipotoxicity; Renin angiotensin system

Indexed keywords

ADENYLATE KINASE; BENIDIPINE; CARNITINE PALMITOYLTRANSFERASE I; CD36 ANTIGEN; FAT DROPLET; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LOSARTAN; LOW DENSITY LIPOPROTEIN RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; SUPEROXIDE; TRIACYLGLYCEROL; UNCOUPLING PROTEIN 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CREATININE CLEARANCE; FATTY ACID OXIDATION; GENE EXPRESSION REGULATION; KIDNEY MASS; LIPID STORAGE; METABOLIC SYNDROME X; NONHUMAN; OTSUKA LONG EVANS TOKUSHIMA FATTY RAT; PROTEIN PHOSPHORYLATION; PROTEINURIA; RAT;

AMP-ACTIVATED PROTEIN KINASES; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; CALCIUM CHANNEL BLOCKERS; CARNITINE O-PALMITOYLTRANSFERASE; CHOLESTEROL; DIHYDROPYRIDINES; DISEASE MODELS, ANIMAL; KIDNEY; LIPID METABOLISM; LOSARTAN; MALE; METABOLIC SYNDROME X; RATS; RATS, INBRED OLETF; RATS, LONG-EVANS; SUPEROXIDES; TRIGLYCERIDES;

EID: 77749233936     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1038/hr.2009.224     Document Type: Article

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