Levamisole and ryanodine receptors (I): A contraction study in Ascaris suum

Molecular and Biochemical Parasitology

Volumn 171, Issue 1, 2010, Pages 1-7

  Robertson, Alan P ^a   Clark, Cheryl L ^a   Martin, Richard J ^a  

^a IOWA STATE UNIVERSITY   (United States)

Author keywords

AF2; Ascaris suum; Caffeine; Contraction; Levamisole; Ryanodine

Indexed keywords

CAFFEINE; DANTROLENE; LEVAMISOLE; NEUROPEPTIDE; PROTEIN AF2; RYANODINE RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; ASCARIS SUUM; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; EXCITATION CONTRACTION COUPLING; EXTRACELLULAR CALCIUM; FEMALE; MEMBRANE ELECTROPHYSIOLOGY; MICHAELIS MENTEN KINETICS; MUSCLE CONTRACTION; MUSCLE FLAP; MUSCLE FORCE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; RESPONSE TIME; STIMULUS RESPONSE;

ANIMALS; ANTHELMINTICS; ASCARIS SUUM; CAFFEINE; CALCIUM; CHOLINERGIC AGONISTS; DANTROLENE; FURYLFURAMIDE; LEVAMISOLE; MUSCLE CONTRACTION; RYANODINE; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL;

ASCARIS SUUM;

EID: 77649337309     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2009.12.007     Document Type: Article

References (40)

1. Wolstenholme A.J., Fairweather I., Prichard R., von Samson-Himmelstjerna G., and Sangster N.C. Drug resistance in veterinary helminths. Trends Parasitol 20 (2004) 469-476
2. Aceves J., Erlij D., and Martinez-Maranon R. The mechanism of the paralyzing action of tetramisole on Ascaris somatic muscle. Br J Pharmacol 38 (1970) 602-607
3. Robertson S.J., and Martin R.J. Levamisole-activated single-channel currents from muscle of the nematode parasite Ascaris suum. Br J Pharmacol 108 (1993) 170-178
4. Qian H., Martin R.J., and Robertson A.P. Pharmacology of N-, L- and B-subtypes of nematode nAChR resolved at the single-channel level in Ascaris suum. FASEB J 20 (2006) E2108-E2116
5. Martin R.J., and Robertson A.P. Mode of action of levamisole and pyrantel, anthelmintic resistance, E153 and Q57. Parasitology 134 (2007) 1093-1104
6. Qian F., Robertson A.P., and Martin R.J. Levamisole resolved at the single-channel level in C. elegans. FASEB J 22 (2008) 3247-3254
7. Burr A.H., and Gans C. Mechanical significance of obliquely striated architecture in nematode muscle. Biol Bull 194 (1998) 1-6
8. Verma S., Robertson A.P., and Martin R.J. The nematode neuropeptide, AF2 (KHEYLRF-NH(2)), increases voltage-activated calcium currents in Ascaris suum muscle. Br J Pharmacol 151 (2007) 888-899
9. Stevenson T.O., Mercer K.B., Cox E.A., et al. Unc-94 encodes a tropomodulin in Caenorhabditis elegans. J Mol Biol 374 (2007) 936-950
10. Maryon E.B., Saari B., and Anderson P. Muscle-specific functions of ryanodine receptor channels in Caenorhabditis elegans. J Cell Sci 111 (1998) 2885-2895
11. Maryon E.B., Coronado R., and Anderson P. unc-68 encodes a ryanodine receptor involved in regulating C. elegans body-wall muscle contraction. J Cell Biol 134 (1996) 885-893
12. Rosenbluth J. Ultrastructure of somatic muscle cells in Ascaris lumbricoides. II. Intermuscular junctions, neuromuscular junctions, and glycogen stores. J Cell Biol 26 (1965) 579-591
13. Rosenbluth J. Ultrastructural organization of obliquely striated muscle fibers in Ascaris lumbricoides. J Cell Biol 25 (1965) 495-515
14. Trailovic S.M., Clark C.L., Robertson A.P., and Martin R.J. Brief application of AF2 produces long lasting potentiation of nAChR responses in Ascaris suum. Mol Biochem Parasitol 139 (2005) 51-64
15. Sattelle D.B., Cordova D., and Cheek T.R. Insect ryanodine receptors: molecular targets for novel pest control chemicals. Invert Neurosci 8 (2008) 107-119
16. Kim Y.K., Valdivia H.H., Maryon E.B., Anderson P., and Coronado R. High molecular weight proteins in the nematode C. elegans bind [3H]ryanodine and form a large conductance channel. Biophys J 63 (1992) 1379-1384
17. Reinitz C.A., Herfel H.G., Messinger L.A., and Stretton A.O.W. Changes in locomotory behavior and cAMP produced in Ascaris suum by neuropeptides from Ascaris suum or Caenorhabditis elegans. Mol Biochem Parsitol 111 (2000) 185-197
18. Krause T., Gerbershagen M.U., Fiege M., Weisshorn R., and Wappler F. Dantrolene-a review of its pharmacology, therapeutic use and new developments. Anaesthesia 59 (2004) 64-373
19. 2+ release mechanism in non-excitable cells (review). Int J Mol Med 7 (2001) 21-25
20. Anderson P. Molecular genetics of nematode muscle. Ann Rev Genet 23 (1989) 507-525
21. Ogawa Y., Kurebayashi N., and Murayama T. Putative roles of type 3 ryanodine receptor isoforms (RyR3). Trends Cardiovasc Med 10 (2000) 65-70
22. del Castillo C.J., De Mello W.C., and Morales T. The initiation of action potentials in the somatic musculature of Ascaris lumbricoides. J Exp Biol 46 (1967) 263-279
23. Weisblat D.P., Byerly L., and Russel R.L. Ionic Mechanisms of electrical activity in the somatic muscle cell of the nematode Ascaris lumbricoides. J Comp Physiol 111 (1976) 93-113
24. Berridge M.J. Smooth muscle cell calcium activation mechanisms. J Physiol 586 (2008) 5047-5061
25. Albert A.P., Saleh S.N., Peppiatt-Wildman C.M., and Large W.A. Multiple activation mechanisms of store-operated TRPC channels in smooth muscle cells. J Physiol 583 (2007) 25-36
26. Williamson S.M., Robertson A.P., Brown L., et al. The nicotinic acetylcholine receptors of the parasitic nematode Ascaris suum: formation of two distinct drug targets by varying the relative expression levels of two subunits. PLoS Pathog 5 (2009) e1000517 10.1371/journal.ppat.1000517
27. Hobson A.D., Stephenenson W., and Eden A. Studies on the physiology of Ascaris lumbricoides. II. The inorganic composition of the body fluid in relation to that of the environment. J Exp Biol 29 (1952) 22-29
28. 2+ depletion. PNAS 98 (2001) 13625-13630
29. Dipolo R., and Beaugé L. Sodium/calcium exchanger: influence of metabolic regulation on ion carrier interactions. Physiol Rev 86 (2006) 155-203
30. Xu L., Tripathy A., Pasek D.A., and Meissner G. Potential for pharmacology of ryanodine receptor/calcium release channels. Ann NY Acad Sci 853 (1998) 130-148
31. Lewis J.A., Wu C.H., Berg H., and Levine J.H. The genetics of levamisole resistance in the nematode Caenorhabditis elegans. Genetics 95 (1980) 905-928
32. Benian G.M., L'Hernault S.W., and Morris M.E. Additional sequence complexity in the muscle gene, unc-22, and its encoded protein, twitchin, of Caenorhabditis elegans. Genetics 134 (1993) 1097-1104
33. Kagawa H., Takuwa K., and Sakube Y. Mutations and expressions of the tropomyosin gene and the troponin C gene of Caenorhabditis elegans. Cell Struct Funct 22 (1997) 213-218
34. Fleming J.T., Squire M.D., Barnes T.M., et al. Caenorhabditis elegans levamisole resistance genes lev-1, unc-29, and unc-38 encode functional nicotinic acetylcholine receptor subunits. J Neurosci 17 (1997) 5843-5857
35. Jones A.K., and Sattelle D.B. Functional genomics of the nicotinic acetylcholine receptor gene family of the nematode, Caenorhabditis elegans. Bioessays 26 (2004) 39-49
36. Culetto E., Baylis H.A., Richmond J.E., et al. The Caenorhabditis elegans unc-63 gene encodes a levamisole-sensitive nicotinic acetylcholine receptor alpha subunit. J Biol Chem 279 (2004) 42476-42483
37. Gally C., Eimer S., Richmond J.E., and Bessereau J.L. A transmembrane protein required for acetylcholine receptor clustering in Caenorhabditis elegans. Nature 431 (2004) 578-582
38. Towers P.R., Edwards B., Richmond J.E., and Sattelle D.B. The Caenorhabditis elegans lev-8 gene encodes a novel type of nicotinic acetylcholine receptor alpha subunit. J Neurochem 93 (2005) 1-9
39. Touroutine D., Fox R.M., Von Stetina S.E., Burdina A., Miller D.M., and Richmond J.E. acr-16 encodes an essential subunit of the levamisole-resistant nicotinic receptor at the Caenorhabditis elegans neuromuscular junction. J Biol Chem 280 (2005) 27013-27021
40. Jones A.K., Buckingham S.D., and Sattelle D.B. Chemistry-to-gene screens in Caenorhabditis elegans. Nat Rev Drug Discov 4 (2005) 321-330