Frequency and circumstances of placebo use in clinical practice - a systematic review of empirical studies

BMC Medicine

Volumn 8, Issue , 2010, Pages

  Fässler, Margrit ^a   Meissner, Karin ^b,c   Schneider, Antonius ^c   Linde, Klaus ^c  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF MUNICH   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PLACEBO;

ARTICLE; CLINICAL PRACTICE; CLINICAL RESEARCH; DOCTOR PATIENT RELATION; FREQUENCY ANALYSIS; HEALTH PERSONNEL ATTITUDE; HUMAN; MOTIVATION; NURSE; PATIENT CARE; PHYSICIAN; PLACEBO EFFECT; PROFESSIONAL PRACTICE; QUALITATIVE ANALYSIS; SYSTEMATIC REVIEW; ATTITUDE TO HEALTH; BIOETHICS; CLINICAL TRIAL; EMPIRICAL RESEARCH; ETHICS; HEALTH CARE PERSONNEL; METHODOLOGY; PSYCHOLOGICAL ASPECT; QUESTIONNAIRE; REVIEW; STATISTICS;

BIOETHICS; CLINICAL TRIALS AS TOPIC; EMPIRICAL RESEARCH; HEALTH KNOWLEDGE, ATTITUDES, PRACTICE; HEALTH PERSONNEL; HUMANS; PLACEBOS; QUESTIONNAIRES;

EID: 77649333613     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/1741-7015-8-15     Document Type: Article

References (40)

1. Macedo A, Farré M, Banos JE. Placebo effect and placebos: what are we talking about? Some conceptual and historical considerations. Eur J Clin Pharmacol 2003, 59:337-342. 10.1007/s00228-003-0612-4, 12830339.
2. Grünbaum A. The placebo concept. Behav Res Ther 1981, 19:157-167. 10.1016/0005-7967(81)90040-1, 7271692.
3. Gøtzsche PC. Is there logic in the placebo?. Lancet 1994, 344:925-926. 10.1016/S0140-6736(94)92273-X, 7934350.
4. Moerman DE, Jonas WB. Deconstructing the placebo effect and finding the meaning response. Ann Intern Med 2002, 136:471-476.
5. Shapiro AK, Morris LA. The placebo effect in medical and psychological therapies. Handbook of Psychotherapy and Behaviour Change 1978, 369-410. New York: Wiley, Garfield SJ, Bergin AE, 2.
6. Biller-Andorno N. The use of the placebo effect in clinical medicine - ethical blunder or ethical imperative?. Sci Eng Ethics 2004, 10:43-50. 10.1007/s11948-004-0061-1, 14986770.
7. Lynöe N. Ethical and professional aspects of the practice of alternative medicine. Scand J Soc Med 1992, 20:217-225.
8. Rich BA. A placebo for the pain: a medico-legal case analysis. Pain Med 2003, 4:366-372. 10.1111/j.1526-4637.2003.03046.x, 14750916.
9. Anonymous Umfrage - plazeboverordnung. Päd Praxis 1976, 16:663-679. Anonymous.
10. Hofling CK. The place of placebos in medical practice. GP 1955, 11(6):103-107.
11. Jores A, Kleinsorge H, Lendle L, Martini P, Schmelcher R. Umfrage zum placebo-problem [Survey on the problem of placebo use]. Medizinische 1956, 24:1238-1246.
12. Shapiro AK. Attitudes toward the use of placebos in treatment. J Nerv Ment Dis 1960, 130:200-211.
13. Lynöe N, Svensson T. Physicians and alternative medicine - an investigation of attitudes and practice. Scan J Soc Med 1992, 20:55-60.
14. Norheim AJ, Fønnebø V. Attitudes to the contribution of placebo in acupuncture - a survey. Complement Ther Med 2002, 10:202-209. 10.1016/S0965-2299(02)00091-2, 12594970.
15. Shapiro AK, Struening EL. The use of placebos: a study of ethics and physicians' attitudes. Psychiatry Med 1973, 4:17-29.
16. Shapiro AK, Struening E. Defensiveness in the definition of placebo. Compr Psychiatry 1973, 14:107-120. 10.1016/0010-440X(73)90003-5, 4704546.
17. Comaroff J. A bitter pill to swallow: placebo therapy in general practice. Sociol Rev 1976, 24:79-96.
18. Goldberg RJ, Leigh H, Quinlan D. The current status of placebo in hospital practice. Gen Hosp Psychiatry 1979, 1:196-201. 10.1016/0163-8343(79)90019-7, 499792.
19. Goodwin JS, Goodwin JM, Vogel AV. Knowledge and use of placebos by house officers and nurses. Ann Intern Med 1979, 91:106-110.
20. Gray G, Flynn P. A survey of placebo use in a general hospital. Gen Hosp Psychiatry 1981, 3:199-203. 10.1016/0163-8343(81)90002-5, 7286642.
21. Lange HU. Zur Praxis der Placebobehandlung in einer psychiatrischen Klinik. [The status of placebo treatment in a psychiatric hospital]. (author's translation) Psychiatr Prax 1981, 8:147-151.
22. Thomson RJ, Buchanan WJ. Placebos and general practice: attitudes to, and the use of, the placebo effect. N Z Med J 1982, 95:492-494.
23. Classen W, Feingold E. Use of placebos in medical practice. Pharmacopsychiat 1985, 18:131-132.
24. Saupe R. The use of placebo as seen by nursing staff. Pharmacopsychiat 1986, 19:347-348.
25. Schwartz RK, Soumerai SB, Avorn J. Physician motivations for nonscientific drug prescribing. Soc Sci Med 1989, 28:577-582. 10.1016/0277-9536(89)90252-9, 2648605.
26. Lynöe N, Mattsson B, Sandlund M. The attitudes of patients and physicians towards placebo treatment - a comparative study. Soc Sci Med 1993, 36:767-574. 10.1016/0277-9536(93)90037-5, 8480221.
27. Ernst E, Abbot NC. Placebos in clinical practice: Results of a survey of nurses. Perfusion 1997, 10:128-130.
28. Berger JT. Placebo medication use in patient care: a survey of medical interns. West J Med 1999, 170:93-96. 1305448, 10063395.
29. Berthelot JM, Maugars Y, Abgrall M, Prost A. Interindividual variations in beliefs about the placebo effect: a study in 300 rheumatology inpatients and 100 nurses. Joint Bone Spine 2001, 68:65-70. 10.1016/S1297-319X(00)00225-6, 11235784.
30. Hróbjartsson A, Norup M. The use of placebo interventions in medical practice - a national questionnaire survey of Danish clinicians. Eval Health Prof 2003, 26:153-165. 10.1177/0163278703026002002, 12789709.
31. Nitzan U, Lichtenberg P. Questionnaire survey on use of placebo. BMJ 2004, 329:944-946. 10.1136/bmj.38236.646678.55, 524103, 15377572.
32. Lim EC, Seet RC. Attitudes of medical students to placebo therapy. Intern Med J 2007, 37:156-160. 10.1111/j.1445-5994.2007.01264.x, 17316333.
33. Sherman R, Hickner J. Academic physicians use placebos in clinical practice and believe in the mind-body connection. J Gen Intern Med 2008, 23:7-10. 10.1007/s11606-007-0332-z, 2173915, 17994270.
34. Tilburt JC, Emanuel EJ, Kaptchuk TJ, Curlin FA, Miller FG. Prescribing 'placebo treatments': results of national survey of US internists and rheumatologists. BMJ 2008, 337:a1938. 10.1136/bmj.a1938, 2572204, 18948346.
35. Bernateck M, Karst M, Eberhard S, Vivell W, Fischer MJ, Stichtenoth DO. Placebotherapie: Analyse von Umfang und Erwartung in einer Klinik der Maximalversorgung [Placebo therapy: analysis of extent and expectations in a tertiary referral center.]. Schmerz 2009, 23:47-53. 10.1007/s00482-008-0733-x, 19050936.
36. Chen GF, Johnson MH. Patients' attitudes to the use of placebo: results from a New Zealand survey. N Z Med J 2009, 122:35-46.
37. Fässler M, Gnädinger M, Rosemann T, Biller-Andorno N. Use of placebo interventions among Swiss primary care providers. BMC Health Serv Res 2009, 9:144. 10.1186/1472-6963-9-144, 2731747, 19664267.
38. Kumar S, Little P, Britten N. Why do general practitioners prescribe antibiotics for sore throat? Grounded theory interview study. BMJ 2003, 326:138. 10.1136/bmj.326.7381.138, 140007, 12531847.
39. Enck P, Benedetti F, Schedlowski M. New insights into the placebo and nocebo responses. Neuron 2008, 59:195-206. 10.1016/j.neuron.2008.06.030, 18667148.
40. Butler CC, Rollnick S, Pill R, Maggs-Rapport F, Stott N. Understanding the culture of prescribing: qualitative study of general practitioners' and patients' perceptions of antibiotics for sore throats. BMJ 1998, 317:637-642. 28658, 9727992.