Accelerated hypofractionated radiotherapy as adjuvant regimen after conserving surgery for early breast cancer: Interim report of toxicity after a minimum follow up of 3 years

Journal of Experimental and Clinical Cancer Research

Volumn 29, Issue 1, 2010, Pages

  Pinnaro, Paola ^a   Soriani, Antonella ^a   Landoni, Valeria ^a   Giordano, Carolina ^a   Papale, Maria ^a   Marsella, Annelisa ^a   Marucci, Laura ^a   Arcangeli, Giorgio ^a   Strigari, Lidia ^a  

^a REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANASTROZOLE; CYCLOPHOSPHAMIDE; DOCETAXEL; EPIRUBICIN; FLUOROURACIL; METHOTREXATE; TAMOXIFEN;

ACCELERATED HYPOFRACTIONATED RADIOTHERAPY; ADULT; AGED; ARTICLE; BREAST ADENOCARCINOMA; BREAST CANCER; BREAST SURGERY; CANCER ADJUVANT THERAPY; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CHI SQUARE TEST; CLINICAL ARTICLE; COMPUTED TOMOGRAPHY SCANNER; COMPUTER ASSISTED TOMOGRAPHY; DISEASE FREE SURVIVAL; FOLLOW UP; HORMONAL THERAPY; HUMAN; LUNG FUNCTION TEST; LUNG TOXICITY; MULTIMODALITY CANCER THERAPY; PRIORITY JOURNAL; RADIATION DOSE; RADIOLOGIST; RANK SUM TEST; SKIN TOXICITY; STUDENT T TEST; TELANGIECTASIA; TREATMENT DURATION; ADENOCARCINOMA; ADJUVANT THERAPY; BREAST TUMOR; CLINICAL TRIAL; FEASIBILITY STUDY; FEMALE; LUNG; MIDDLE AGED; RADIATION DOSE FRACTIONATION; RADIATION EXPOSURE; RADIOTHERAPY; SEGMENTAL MASTECTOMY; SKIN;

ADENOCARCINOMA; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; DOSE FRACTIONATION; FEASIBILITY STUDIES; FEMALE; FOLLOW-UP STUDIES; HUMANS; LUNG; MASTECTOMY, SEGMENTAL; MIDDLE AGED; RADIOTHERAPY; RADIOTHERAPY, ADJUVANT; SKIN;

EID: 77649298685     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/1756-9966-29-9     Document Type: Article

References (30)

1. Radiotherapy after breast-conserving surgery in small breast carcinoma. Long-term results of a randomized trial. U Veronesi E Marubini L Mariani V Galimberti A Luini P Veronesi B Salvadori R Zucali, Ann Oncol 2000 12 997 1003 10.1023/A:1011136326943
2. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy and lumpectomy plus irradiation for the treatment of invasive breast cancer. B Fisher S Anderson J Bryant RG Margolese M Deutsch ER Fisher JH Jeong N Wolmark, N Engl J Med 2002 347 1233 1241 10.1056/NEJMoa022152 12393820
3. Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials. Early Breast Cancer Trialist's Collaborative Group, Lancet 2005 366 2087 2106 16360786
4. The linear-quadratic formula and progress in fractionated radiotherapy. JF Fowler, Br J Radioll 1989 62 679 94 10.1259/0007-1285-62-740-679
5. Randomized trial of breast irradiation schedules after lumpectomy for women with lymph node-negative breast cancer. T Whelan R MacKenzie J Julian M Levine W Shelley L Grimard B Lada H Lukka F Perera A Fyles E Laukkanen S Gulavita V Benk B Szechtman, J Natl Cancer Inst 2002 94 1143 1150 12165639
6. Fractionation sensitivity and dose response of late dverse effects in the breast after radiotherapy for early breast cancer: Long term results of a randomized trial. J Yarnold A Ashton J Bliss J Homewood C Harper J Hanson J Haviland S Bentzen R Owen, Radiother Oncol 2005 75 9 17 10.1016/j.radonc.2005. 01.005 15878095
7. Effect of radiotherapy fraction size on tumour control in patients with early-stage breast cancer after local tumour excision: Long term results of randomized trial. JR Owen A Ashton JM Bliss J Homewood C Harper J Hanson J Haviland SM Bentzen JR Yarnold, Lancet 2006 7 467 471 10.1016/S1470-2045(06) 70699-4
8. The UK Standardisation of breast radiotherapy (START) Trial A of radiotherapy hypofractionation for treatment of early breast cancer: a randomized trial. The START Trialists' Group, Lancet Oncol 2008 9 331 341 10.1016/S1470-2045(08)70077-9 18356109
9. The UK Standardisation of breast radiotherapy (START) Trial B of radiotherapy hypofractionation for treatment of early breast cancer: a randomized trial. The START Trialists' Group, Lancet 2008 371 1098 1107 10.1016/S0140-6736(08)60348-7 18355913
10. Hypofractionation for prostate cancer radiotherapy - What are the issues? DJ Brenner, Int J Radiat Oncol Biol Phys 2003 57 912 914 14575821
11. A new isoeffect curve for change in dose per fraction. HR Withers HD Thames LJ Peters, Radiother Oncol 1983 1 187 91 10.1016/S0167-8140(83)80021-8 6680223
12. Basic clinical radiobiology. GG Steel, London: Arnold 3 2002 134 146
13. Preliminary results of electron intraoperative therapy boost and hypofractionated external beam radiotherapy after breast-conserving surgery in premenopausal women. GB Ivaldi MC Leonardi R Orecchia D Zerini A Morra V Galimberti G Gatti A Luini P Veronesi M Ciocca C Sangalli C Fodor U Veronesi, Int J Radiat Oncol Biol Phys 2008 72 2 485 93 Epub 2008 Apr 11 18407434
14. Hypofractionated and accelerated radiotherapy with cytoprotection (HypoARC): a short, safe, and effective postoperative regimen for high-risk breast cancer patients. MI Koukourakis A Giatromanolaki C Kouroussis S Kakolyris E Sivridis C Frangiadaki G Retalis V Georgoulias Tumor and Angiogenesis Research Group, Int J Radiat Oncol Biol Phys 2002 52 1 144 55 11777632
15. Computed tomography (CT) scan evaluation of late toxicity following hypofractionated/accelerated radiotherapy with cytoprotection (HypoARC) in breast cancer patients treated with conservative surgery. J Manavis J Ambatzoglou K Sismanidou MI Koukourakis, Am J Clin Oncol 2006 29 5 479 83 10.1097/01.coc.0000227482.36289.f2 17023783
16. Prescribing, recording and reporting photon beam therapy: ICRU report 50 Bethesda: International Commission on Radiation Units and Measurements. International Commission on Radiation Units and Measurements, 1993
17. Correlation of dosimetric factors and radiation pneumonitis for non-small-cell lung cancer patients in a recently completed dose escalation study. ED Yorke A Jackson KE Rosenzweig L Braban SA Leibel CC Ling, Int J Radiat Oncol Biol Phys 2005 63 672 682 15939548
18. Clinical dose-volume histogram analysis for pneumonitis after 3D treatment for non-small cell lung cancer (NSCLC). MV Graham JA Purdy B Emami W Harms W Bosch MA Lockett CA Perez, Int J Radiat Oncol Biol Phys 1999 45 323 329 10487552
19. Lung volumes and forced ventilatory flows Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal Official Statement of the European Respiratory Society. PH Quanjer GJ Tammeling JE Cotes OF Pedersen R Peslin JC Yernault, Eur Respir J 1993 6 Suppl 16 5 40 8381090
20. Natural course of treated pulmonary embolism Evaluation by perfusion lung scintigraphy, gas exchange, and chest roentgenogram. R Prediletto P Paoletti E Fornai A Perissinotto S Petruzzelli B Formichi S Ruschi A Palla A Giannella-Neto C Giuntini, Chest 1990 97 3 554 61 10.1378/chest.97.3.554 2106409
21. COMMON TOXICITY CRITERIA (CTC), http://ctep.cancer.gov/ protocolDevelopment/electronic-applications/docs/ctcv20-4-30-992.pdf
22. LENT SOMA, Tables Radiother Oncol 1995 35 17 60 10.1016/0167-8140(95) 90055-1
23. Version 4.02. Common Terminology Criteria for Adverse Events (CTCAE), http://evs.nci.nih.gov/ftp1/CTCAE/CTCAE-4.02-2009-09-15-QuickReference-8.5x11. pdf
24. Analysis of radiation pneumonitis and radiation-induced lung fibrosis in breast cancer patients after breast conservation treatment. A Nishioka Y Ogawa N Hamada M Terashima T Inomata S Yoshida, Oncol Rep 1999 6 513 517 10203583
25. Early response of lung in breast cancer irradiation: radiologic density changes measured by ct and symptomatic radiation pneumonitis. B Wennberg G Gagliardi L Sundbom G Svane P Lind, Int J Radiat Oncol Biol Phys 2002 52 1196 1206 10.1016/S0360-3016(01)02770-5 11955730
26. Randomized phase III study comparing Best Supportive Care to Biafine as a prophylactic agent for radiation-induced skin toxicity for women undergoing breast irradiation: Radiation Therapy Oncology Group (RTOG) 97-13. J Fisher C Scott R Stevens B Marconi L Champion GM Freedman F Asrari MV Pilepich JD Gagnon G Wong, Int J Radiat Oncol Biol Phys 2000 48 5 1307 10 11121627
27. Pulmonary function following adjuvant chemotherapy and radiotherapy for breast cancer and the issue of three-dimensional treatment planning. PA Lind S Rosfors B Wennberg U Glas S Bevegård T Fornander, Radiother Oncol 1998 49 245 54 10.1016/S0167-8140(98)00121-2 10075257
28. Radiation induced lung reactions in breast cancer therapy. Modulating factors and consequential effects. W Dörr S Bertmann T Herrmann, Strahlenther Onkol 2005 181 9 567 73 10.1007/s00066-005-1457-9 16170483
29. Radiotherapy-related lung fibrosis enhanced by tamoxifen. SM Bentzen JZ Skoczylas M Overgaard J Overgaard, J Natl Cancer Inst 1996 88 13 918 22 10.1093/jnci/88.13.918 8656444
30. Decline in pulmonary function in patients with breast cancer receiving dose-dense chemotherapy: a prospective study. R Yerushalmi MR Kramer S Rizel A Sulkes K Gelmon T Granot V Neiman SM Stemmer, Ann Oncol 2009 20 3 437 40 Epub 2009 Jan 12 10.1093/annonc/mdn652 19139179