Prevention of oxidative damage to lens by caffeine

Journal of Ocular Pharmacology and Therapeutics

Volumn 26, Issue 1, 2010, Pages 73-77

  Varma, Shambhu D ^a   Hegde, Kavita R ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATE; CAFFEINE; GLUTATHIONE; HYDROXYL RADICAL; IRON COMPLEX; REACTIVE OXYGEN METABOLITE; RUBIDIUM; TEMPOL;

ANIMAL TISSUE; ARTICLE; CATARACT; CATARACTOGENESIS; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; EYE PROTECTION; LENS; MOUSE; NONHUMAN; OXIDATIVE STRESS;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIOXIDANTS; BIOLOGICAL TRANSPORT; CAFFEINE; CYCLIC N-OXIDES; FREE RADICAL SCAVENGERS; GLUTATHIONE; HYDROXYL RADICAL; IRON COMPOUNDS; LENS, CRYSTALLINE; MICE; MICE, INBRED STRAINS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RUBIDIUM; SODIUM-POTASSIUM-EXCHANGING ATPASE; SPIN LABELS;

EID: 77649291924     PISSN: 10807683     EISSN: None     Source Type: Journal    
DOI: 10.1089/jop.2009.0097     Document Type: Article

References (31)

1. Varma, S.D., Ets, T.K., and Richards, R.D. Protection against superoxide radicals in rat lens. Ophthalmic Res. 9: 421 - 431, 1977.
2. Bhuyan, D.K., and Bhuyan, K.C. Superoxide dismutase of the eye: relative functions of superoxide dismutase and catalase in protecting the ocular lens from oxidative damage. Biochim. Biophys. Acta. 542: 28 - 38, 1978.
3. Fridovich, I. Superoxide dismutases. Annu. Rev. Biochem. 44: 147 - 159, 1975.
4. Halliwell, B. The biological effects of the superoxide radical and its products. Bull. Eur. Physiopathol. Respir. 17(Suppl): 21 - 29, 1981.
5. Fenton, H.J.H., and Jones, H.O. The oxidation of organic acids in presence of ferrous iron, Part I. J. Chem. Soc. Trans. 77: 69 - 76, 1900.
6. Haber, F., and Weiss, J. The catalytic decomposition of hydrogen peroxide by iron salts. Proc. Roy. Soc. London, Series A. 147: 332 - 351, 1934.
7. Taylor, H.R., West, S.K., Rosenthal, F.S., et al. Effect of ultraviolet radiation on cataract formation. N. Engl. J. Med. 319: 1429 - 1433, 1988.
8. Varma, S.D., Chand, D., Sharma, Y.R., et al. Oxidative stress on lens and cataract formation: role of light and oxygen. Curr. Eye Res. 3: 35 - 57, 1984.
9. Varma, S.D., Kumar, S., and Richards, R.D. Light-induced damage to ocular lens cation pump: prevention by vitamin C. Proc. Natl. Acad. Sci. USA 76: 3504 - 3506, 1979.
10. Varma, S.D., Hegde, K., and Henein, M. Oxidative damage to mouse lens in culture. Protective effect of pyruvate. Biochim. Biophys. Acta. 1621: 246 - 252, 2003.
11. Zigler, J.S. Jr, and Goosey, J.D. Singlet oxygen as a possible factor in human senile nuclear cataract development. Curr. Eye Res. 3: 59 - 65, 1984.
12. Behndig, A., Karlsson, K., Reaume, A.G., et al. In vitro photo-chemical cataract in mice lacking copper-zinc superoxide dismutase. Free Radic. Biol. Med. 31: 738 - 744, 2001.
13. Ayala, M.N., Michael, R., and Söderberg, P.G. In vivo cataract after repeated exposure to ultraviolet radiation. Exp. Eye Res. 70: 451 - 456, 2000.
14. Spector, A. Oxidative stress-induced cataract: mechanism of action. FASEB J. 9: 1173 - 1182, 1995.
15. Hegde, K.R., and Varma, S.D. Morphogenetic and apoptotic changes in diabetic cataract: prevention by pyruvate. Mol. Cell. Biochem. 262: 233 - 237, 2004.
16. Varma, S.D. Ascorbic acid and the eye with special reference to the lens. Ann. N. Y. Acad. Sci. 498: 280 - 306, 1987.
17. Trevithick, J.R., Linklater, H.A., Mitton, K.P., et al. Modeling cortical cataractogenesis: IX. Activity of vitamin E and esters in preventing cataracts and gamma-crystallin leakage from lenses in diabetic rats. Ann. N. Y. Acad. Sci. 570: 358 - 371, 1989.
18. Ayala, M.N., and Söderberg, P.G. Vitamin E can protect against ultraviolet radiation-induced cataract in albino rats. Ophthalmic Res. 36: 264 - 269, 2004.
19. Varma, S.D., Mizuno, A., and Kinoshita, J.H. Diabetic cataracts and flavonoids. Science. 195: 205 - 206, 1977.
20. Varma, S.D., Hegde, K.R., and Kovtun, S. UV-B-induced damage to the lens in vitro: prevention by caffeine. J. Ocul. Pharmacol. Ther. 24: 439 - 444, 2008.
21. Strehler, B.J., and Totter, J.K. Determination of ATP and related compounds: fi refly luminescence and other methods. In: Glick, D., ed. Methods of Biochemical Analysis Vol. 1. New York: Interscience Publishers; 1954; p. 341.
22. Ellman, G.L. Tissue sulfhydryl groups. Arch. Biochem. Biophys. 82: 70 - 77, 1959.
23. Kuszak, J.R., and Costello, M.J. The structure of the vertebrate lens. In: Lovicu, F.J., and Robinson, M.L., eds. Development of the Ocular Lens. New York: Cambridge University Press; 2004; p. 71 - 118.
24. Bhuyan, K.C., Bhuyan, D.K., and Podos, S.M. Lipid peroxidation in cataract of the human. Life Sci. 38: 1463 - 1471, 1986.
25. Varma, S.D., Beachy, N.A., and Richards, R.D. Photoperoxidation of lens lipids: prevention by vitamin E. Photochem. Photobiol. 36: 623 - 626, 1982.
26. Prchal, J., Srivastava, S.K., and Beutler, E. Active transport of GSSG from reconstituted erythrocyte ghosts. Blood. 46: 111 - 117, 1975.
27. Krishna, M.C., Russo, A., Mitchell, J.B., et al. Do nitroxide anti-oxidants act as scavengers of O2-. or as SOD mimics? J. Biol. Chem. 271: 26026 - 26031, 1996.
28. Saito, K., Takeshita, K., Ueda, J., et al. Two reaction sites of a spin label, Tempol (4-hydroxy-2,2,6,6-tetramethylpiperidine-N-oxyl), with hydroxyl radical. J. Pharm. Sci. 92: 275 - 280, 2003.
29. Devasagayam, T.P., Kamat, J.P., Mohan, H., et al. Caffeine as an antioxidant: inhibition of lipid peroxidation induced by reactive oxygen species. Biochim. Biophys. Acta. 1282: 63 - 70, 1996.
30. Shi, X., Dalal, N.S., and Jain, A.C. Antioxidant behaviour of caffeine: effi cient scavenging of hydroxyl radicals. Food Chem. Toxicol. 29: 1 - 6, 1991.
31. Stadler, R.H., and Fay, L.B. Antioxidative reactions of caffeine: formation of 8-oxocaffeine (1,3,7 trimethyl uric acid) in coffee subjected to oxidative stress. J. Agric. Food Chem. 43: 1332 - 1338, 1995.