Vertebroplasty: when randomized placebo-controlled trial results clash with common belief

Spine Journal

Volumn 10, Issue 3, 2010, Pages 241-243

  Buchbinder, Rachelle ^a   Kallmes, David F ^b  

^a CABRINI HOSPITAL   (Australia)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANESTHETIC AGENT; PLACEBO;

ARTICLE; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; DISABILITY; DISEASE SEVERITY; FRAGILITY FRACTURE; HUMAN; INVASIVE PROCEDURE; LOW BACK PAIN; MEDICAL SOCIETY; NUCLEAR MAGNETIC RESONANCE IMAGING; OSTEOPOROTIC VERTEBRAL COMPRESSION FRACTURE; OUTCOME ASSESSMENT; PATIENT SAFETY; PATIENT SELECTION; PERCUTANEOUS VERTEBROPLASTY; PRIORITY JOURNAL; RISK; SPINAL PAIN; SURGICAL TECHNIQUE; SYMPTOM; TREATMENT OUTCOME; TREATMENT RESPONSE; VERTEBRA FRACTURE;

EID: 77649286539     PISSN: 15299430     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.spinee.2010.01.001     Document Type: Note

References (14)

1. Bono L., Heggeness M., Mick C., et al. Newly released vertebroplasty RCTs: a tale of two trials. Spine J 10 (2010) 238-240
2. Álvarez L., Alcarez M., Pérez-Higueras A., et al. Percutaneous vertebroplasty: functional improvement in patients with osteoporotic compression fractures. Spine 31 (2006) 1113-1118
3. Diamond T.H., Champion B., and Clark W.A. Management of acute osteoporotic vertebral fractures: a nonrandomized trial comparing percutaneous vertebroplasty with conservative therapy. [comment]. Am J Med 114 (2003) 257-265
4. Buchbinder R., Osborne R., Ebeling P., et al. A randomized trial of vertebroplasty for painful osteoporotic vertebral fractures. N Engl J Med 361 (2009) 557-568
5. Kallmes D., Comstock B., Heagerty P., et al. A randomized trial of vertebroplasty for osteoporotic spinal fractures. N Engl J Med 361 (2009) 569-579
6. Hancock M., Herbert R., and Maher C. A guide to interpretation of studies investigating subgroups of responders to physical therapy interventions. Phys Ther 89 (2009) 698-704
7. Buchbinder R., Osborne R., and Staples M. Response to letters to the editor. N Engl J Med 361 (2009) 2099
8. Rousing R., Andersen M., Jespersen S., et al. Percutaneous vertebroplasty compared to conservative treatment in patients with painful acute or subacute osteoporotic vertebral fractures: three-months follow-up in a clinical randomized study. Spine 34 (2009) 1349-1354
9. Voormolen M., Mali W., Lohle P., et al. Percutaneous vertebroplasty compared with optimal pain medication treatment: short-term clinical outcome of patients with subacute or chronic painful osteoporotic vertebral compression fractures. The VERTOS study. AJNR Am J Neuroradiol 28 (2007) 555-560
10. Wardlaw D., Cummings S., Van Meirhaeghe J., et al. Efficacy and safety of balloon kyphoplasty compared with non-surgical care for vertebral compression fracture (FREE): a randomised controlled trial. Lancet 373 (2009) 1016-1024
11. Kallmes D., Comstock B., Gray L., et al. Baseline pain and disability in the Investigational Vertebroplasty Efficacy and Safety Trial. AJNR Am J Neuroradiol 30 (2009) 1203-1205
12. Staal J., de Bie R., de Vet H., et al. Injection therapy for subacute and chronic low-back pain. Cochrane Database Syst Rev (2008) Issue 3. Art. No.: CD001824. 10.1002/14651858.CD001824.pub3
13. Trout A.T., Kallmes D.F., Gray L.A., et al. Evaluation of vertebroplasty with a validated outcome measure: the Roland-Morris Disability Questionnaire. AJNR Am J Neuroradiol 26 (2005) 2652-2657
14. Carey T. Vertebroplasty was not effective for painful osteoporotic vertebral fractures. ACP Journal Club 151 (2009) 8-9