Relationship between selected indoor volatile organic compounds, so-called microbial VOC, and the prevalence of mucous membrane symptoms in single family homes

Science of the Total Environment

Volumn 408, Issue 10, 2010, Pages 2208-2215

  Araki, Atsuko ^a   Kawai, Toshio ^b   Eitaki, Yoko ^b   Kanazawa, Ayako ^b   Morimoto, Kanehisa ^c   Nakayama, Kunio ^c   Shibata, Eiji ^d   Tanaka, Masatoshi ^e   Takigawa, Tomoko ^f   Yoshimura, Takesumi ^g   Chikara, Hisao ^g   Saijo, Yasuaki ^h   Kishi, Reiko ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b JAPAN INDUSTRIAL SAFETY AND HEALTH ASSOCIATION   (Japan)

^c OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d AICHI MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e NATIONAL INSTITUTE OF TECHNOLOGY   (Japan)

^f OKAYAMA UNIVERSITY   (Japan)

^g FUKUOKA INSTITUTE OF HEALTH AND ENVIRONMENTAL SCIENCES   (Japan)

^h ASAHIKAWA MEDICAL COLLEGE   (Japan)

Author keywords

Exposure; Home environment; Indoors; Microbial volatile organic compounds (MVOC); Mucous membrane; Questionnaires; Sick building syndrome; Symptoms

Indexed keywords

1-OCTEN-3-OL; 1-PENTANOL; 2-PENTANOL; AIR SAMPLES; ANIMAL STUDIES; CONFIDENCE INTERVAL; DETECTION RATES; EPIDEMIOLOGICAL STUDIES; GAS CHROMATOGRAPHY/MASS SPECTROMETRY; GEOMETRIC MEAN; HOME ENVIRONMENT; INDOOR AIR; MICROBIAL VOLATILE ORGANIC COMPOUNDS; MUCOUS MEMBRANES; ODDS RATIOS; SAFETY LEVEL; SELECTIVE ION MONITORING; SELF-ADMINISTERED QUESTIONNAIRE; SICK BUILDING SYNDROME; SICK BUILDING SYNDROME SYMPTOMS;

AIR QUALITY; CHROMATOGRAPHIC ANALYSIS; GAS CHROMATOGRAPHY; INTELLIGENT BUILDINGS; SURVEYS; VOLATILE ORGANIC COMPOUNDS;

INDOOR AIR POLLUTION;

1 OCTEN 3 OL; PENTANOL; VOLATILE ORGANIC COMPOUND;

INDOOR AIR; MICROORGANISM; POLLUTION EXPOSURE; QUESTIONNAIRE SURVEY; STATISTICAL ANALYSIS; SYMPTOM; VOLATILE ORGANIC COMPOUND;

AIR SAMPLING; ARTICLE; COUGHING; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL MONITORING; EYE IRRITATION; FAMILY STUDY; HOME ENVIRONMENT; INDOOR AIR POLLUTION; ION MONITORING; MASS FRAGMENTOGRAPHY; MICROBIAL CONTAMINATION; MUCOSAL DISEASE; NOSE IRRITATION; ORGANIC POLLUTION; PREVALENCE; PRIORITY JOURNAL; QUESTIONNAIRE; RESPIRATORY TRACT DISEASE; SICK BUILDING SYNDROME;

AIR MICROBIOLOGY; AIR POLLUTANTS; AIR POLLUTION, INDOOR; CROSS-SECTIONAL STUDIES; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HOUSING; HUMANS; JAPAN; MALE; MUCOUS MEMBRANE; QUESTIONNAIRES; RESPIRATORY TRACT DISEASES; VOLATILE ORGANIC COMPOUNDS;

ANIMALIA;

EID: 77649275024     PISSN: 00489697     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.scitotenv.2010.02.012     Document Type: Article

References (45)

1. Andersson K. Epidemiological approach to indoor air problems. Indoor Air Suppl. 4 (1998) 32-39
2. Araki A., Eitaki Y., Kawai T., Kanazawa A., Takeda K., and Kishi R. Diffusive sampling and measurement of microbial volatile organic compounds in indoor air. Indoor Air 19 (2009) 421-432
3. Borjesson T., Stollman U., and Schnurer J. Volatile metabolites produced by 6 fungal species compared with other indicators of fungal growth on cereal-grains. Appl Environ Microbiol 58 (1992) 2599-2605
4. Borjesson T.S., Stollman U.M., and Schnurer J.L. Off-odorous compounds produced by molds on oatmeal agar - identification and relation to other growth-characteristics. J Agric Food Chem 41 (1993) 2104-2111
5. Bornehag C.G., Blomquist G., Gyntelberg F., Jarvholm B., Malmberg P., Nordvall L., et al. Dampness in buildings and health - Nordic interdisciplinary review of the scientific evidence on associations between exposure to "dampness" in buildings and health effects (NORDDAMP). Indoor Air 11 (2001) 72-86
6. Bornehag C.G., Sundell J., Weschler C.J., Sigsgaard T., Lundgren B., Hasselgren M., et al. The association between asthma and allergic symptoms in children and phthalates in house dust: a nested case-control study. Environ Health Perspect 112 (2004) 1393-1397
7. Bornehag C.G., Sundell J., Sigsgaard T., and Janson S. Potential self-selection bias in a nested case-control study on indoor environmental factors and their association with asthma and allergic symptoms among pre-school children. Scand J Public Health 34 (2006) 534-543
8. Cooley J.D., Wong W.C., Jumper C.A., and Straus D.C. Correlation between the prevalence of certain fungi and sick building syndrome. Occup Environ Med 55 (1998) 579-584
9. Elke K., Begerow J., Oppermann H., Kramer U., Jermann E., and Dunemann L. Determination of selected microbial volatile organic compounds by diffusive sampling and dual-column capillary GC-FID - a new feasible approach for the detection of an exposure to indoor mould fungi?. J Environ Monit 1 (1999) 445-452
10. Engvall K., Norrby C., and Norback D. Ocular, airway, and dermal symptoms related to building dampness and odors in dwellings. Arch Environ Health 57 (2002) 304-310
11. Franchi M., Carrer P., Kotzias D., Rameckers E.M., Seppanen O., van Bronswijk J.E., et al. Working towards healthy air in dwellings in Europe. Allergy 61 (2006) 864-868
12. Garrett M.H., Hooper B.M., and Hooper M.A. Indoor environmental factors associated with house-dust-mite allergen (Der p 1) levels in south-eastern Australian houses. Allergy 53 (1998) 1060-1065
13. Keller R., Senkpiel K., and Butte W. Detection of seasonally dependent MVOC reference values in non-infested apartments. Gefahrstoffe Reinhaltung Der Luft 66 (2006) 107-111
14. Kim J.L., Elfman L., Mi Y., Wieslander G., Smedje G., and Norback D. Indoor molds, bacteria, microbial volatile organic compounds and plasticizers in schools - associations with asthma and respiratory symptoms in pupils. Indoor Air 17 (2007) 153-163
15. Kishi R., Saijo Y., Kanazawa A., Tanaka M., Yoshimura T., Chikara H., et al. Regional differences in residential environments and the association of dwellings and residential factors with the sick house syndrome: a nationwide cross-sectional questionnaire study in Japan. Indoor Air 19 (2009) 243-254
16. Konig G., Brunda M., Puxbaum H., Hewitt C.N., Duckham S.C., and Rudolph J. Relative contribution of oxygenated hydrocarbons to the total biogenic VOC emissions of selected mid-European agricultural and natural plant-species. Atmos Environ 29 (1995) 861-874
17. Korpi A., Pasanen A.L., Pasanen P., and Kalliokoski P. Microbial growth and metabolism in house dust. Int Biodeterior Biodegradation 40 (1997) 19-27
18. Korpi A., Pasanen A.L., and Pasanen P. Volatile compounds originating from mixed microbial cultures on building materials under various humidity conditions. Appl Environ Microbiol 64 (1998) 2914-2919
19. Korpi A., Kasanen J.P., Alarie Y., Kosma V.M., and Pasanen A.L. Sensory irritating potency of some microbial volatile organic compounds (MVOCs) and a mixture of five MVOCs. Arch Environ Health 54 (1999) 347-352
20. Korpi A., Jarnberg J., and Pasanen A.L. Microbial volatile organic compounds. Crit Rev Toxicol 39 (2009) 139-193
21. Matysik S., Herbarth O., and Mueller A. Determination of volatile metabolites originating from mould growth on wall paper and synthetic media. J Microbiol Methods 75 (2008) 182-187
22. Matysik S., Herbarth O., and Mueller A. Determination of microbial volatile organic compounds (MVOCs) by passive sampling onto charcoal sorbents. Chemosphere 76 (2009) 114-119
23. Meyer H.W., Wurtz H., Suadicani P., Valbjorn O., Sigsgaard T., Gyntelberg F., et al. Molds in floor dust and building-related symptoms in adolescent school children. Indoor Air 14 (2004) 65-72
24. Mizoue T., Reijula K., and Andersson K. Environmental tobacco smoke exposure and overtime work as risk factors for sick building syndrome in Japan. Am J Epidemiol 154 (2001) 803-808
25. Nalli S., Horn O.J., Grochowalski A.R., Cooper D.G., and Nicell J.A. Origin of 2-ethylhexanol as a VOC. Environ Pollut 140 (2006) 181-185
26. Ogino S., Enomoto T., and Wada M. Allergic rhinitis and levels of dust-mite allergens in the homes. Pract Otorhinolaryngol (Basel) 95 (2002) 45-50
27. Pasanen A.L., Korpi A., Kasanen J.P., and Pasanen P. Critical aspects on the significance of microbial volatile metabolites as indoor air pollutants. Environ Int 24 (1998) 703-712
28. Saijo Y., Kishi R., Sata F., Katakura Y., Urashima Y., Hatakeyama A., et al. Symptoms in relation to chemicals and dampness in newly built dwellings. Int Arch Occup Environ Health 77 (2004) 461-470
29. Schleibinger H., Keller R., and Ruden H. Indoor air pollution by microorganisms and their metabolites. In: Pluschke P. (Ed). The handbook of environmental chemistry volume 4 air pollution part F (2004), Springer-Verlag Berlin, Heidelberg New York
30. Schleibinger H., Laussmann D., Brattig C., Mangler M., Eis D., and Ruden H. Emission patterns and emission rates of MVOC and the possibility for predicting hidden mold damage?. Indoor Air 15 (2005) 98-104
31. Schleibinger H., Laussmann D., Bornehag C.G., Eis D., and Rueden H. Microbial volatile organic compounds in the air of moldy and mold-free indoor environments. Indoor Air 18 (2008) 113-124
32. Skyberg K., Skulberg K.R., Eduard W., Skaret E., Levy F., and Kjuus H. Symptoms prevalence among office employees and associations to building characteristics. Indoor Air 13 (2003) 246-252
33. Small B.M. Creating mold-free buildings: a key to avoiding health effects of indoor molds. Arch Environ Health 58 (2003) 523-527
34. Smedje G., Norback D., Wessen B., and Edling C. Asthma among school employees in relation to the school environment. Indoor air' 96: proceedings of the 7th international conference on indoor air quality and climate; 1: Sunday & Monday - organizing committee of the 7th international conference of indoor quality and climate. Indoor air' 96: proceedings of the 7th international conference on indoor air quality and climate; 1: Sunday & Monday - organizing committee of the 7th international conference of indoor quality and climate 1 (1996) 611-616
35. Sporik R., Holgate S.T., Platts-Mills T.A., and Cogswell J.J. Exposure to house-dust mite allergen (Der p I) and the development of asthma in childhood. A prospective study. N Engl J Med 323 (1990) 502-507
36. Takahashi T. Airborne fungal colony-forming units in outdoor and indoor environments in Yokohama, Japan. Mycopathologia 139 (1997) 23-33
37. Takeda M., Saijo Y., Yuasa M., Kanazawa A., Araki A., and Kishi R. Relationship between sick building syndrome and indoor environmental factors in newly built Japanese dwellings. Int Arch Occup Environ Health 82 (2009) 583-593
38. Takigawa T., Horike T., Ohashi Y., Kataoka H., Wang D.H., and Kira S.H. Were volatile organic compounds the inducing factors for subjective symptoms of employees working in newly constructed hospitals?. Environ Toxicol 19 (2004) 280-290
39. Takigawa T., Wang B.-L., Sakano N., Wang D.-H., Ogino K., and Kishi R. A longitudinal study of environmental risk factors for subjective symptoms associated with sick building syndrome in new dwellings. Sci Total Environ 407 (2009) 5223-5228
40. Takigawa T., Wang B.-L., Saijo Y., Morimoto K., Nakayama K., Tanaka M., et al. Relationship between indoor chemical concentrations and subjective symptoms associated with sick building syndrome in newly built houses in Japan. Int Arch Occup Environ Health 83 (2010) 225-235
41. van Thriel C., Kiesswetter E., Schaper M., Blaszkewicz M., Golka K., Juran S., et al. From neurotoxic to chemosensory effects: new insights on acute solvent neurotoxicity exemplified by acute effects of 2-ethylhexanol. Neurotoxicology 28 (2007) 347-355
42. Wålinder R., Ernstgard L., Johanson G., Norback D., Venge P., and Wieslander G. Acute effects of a fungal volatile compound. Environ Health Perspect 113 (2005) 1775-1778
43. Wålinder R., Ernstgard L., Norback D., Wieslander G., and Johanson G. Acute effects of 1-octen-3-ol, a microbial volatile organic compound (MVOC) - an experimental study. Toxicol Lett 181 (2008) 141-147
44. Wessen B., and Schoeps K.O. Microbial volatile organic compounds - what substances can be found in sick buildings?. Analyst 121 (1996) 1203-1205
45. Wieslander G., Norback D., and Venge P. Changes of symptoms, tear film stability and eosinophilic cationic protein in nasal lavage fluid after re-exposure to a damp office building with a history of flooding. Indoor Air 17 (2007) 19-27