Red blood cell membrane grafting of multi-functional hyperbranched polyglycerols

Biomaterials

Volumn 31, Issue 14, 2010, Pages 4167-4178

  Rossi, Nicholas A A ^a   Constantinescu, Iren ^a   Kainthan, Rajesh K ^a   Brooks, Donald E ^a   Scott, Mark D ^a   Kizhakkedathu, Jayachandran N ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Antigen masking; Fluorescently labeled polymers; Hyperbranched polyglycerol; Multi functional polymer grafting; Red blood cell surface modification

Indexed keywords

HYPERBRANCHED POLYGLYCEROL; MULTI-FUNCTIONAL; POLYMER GRAFTING; RED BLOOD CELL;

ANTIGENS; BLOOD; CELL MEMBRANES; CHEMICAL DETECTION; CYTOLOGY; DENDRIMERS; ELECTROPHORESIS; FLOW CYTOMETRY; GRAFTING (CHEMICAL); HEMOGLOBIN OXYGEN SATURATION; OXIDATION; POLYMER BLENDS; SURFACE TREATMENT;

FUNCTIONAL POLYMERS;

HYPERBRANCHED POLYGLYCEROL; POLYMER; SUCCINIC ACID; UNCLASSIFIED DRUG;

ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; COVALENT BOND; CYTOLYSIS; ELECTROPHORETIC MOBILITY; ERYTHROCYTE MEMBRANE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LIPID PEROXIDATION; MOLECULAR WEIGHT; OSMOTIC FRAGILITY; PHASE PARTITIONING; POLYMERIZATION; PRIORITY JOURNAL; REACTION TIME;

ANTIBODIES; ERYTHROCYTE MEMBRANE; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENCE; GLYCEROL; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR WEIGHT; OSMOTIC FRAGILITY; POLYMERS; SUCCINIMIDES; TIME FACTORS;

EID: 77649273465     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.01.137     Document Type: Article

References (42)

1. Scott M.D., Murad K.L., Koumpouras F., Talbot M., and Eaton J.W. Chemical camouflage of antigenic determinants: ''Stealth" erythrocytes. Proc Natl Acad Sci USA 94 (1997) 7566-7571
2. Lewis J.D., Destito G., Zijlstra A., Gonzalez M.J., Quigley J.P., Manchester M., et al. Viral nanoparticles as tools for intravital vascular imaging. Nat Med 12 (2006) 354-360
3. Doronin K., Shashkova E.V., May S.M., Hofherr S.E., and Barry M.A. Chemical modification with high molecular weight polyethylene glycol reduces transduction of hepatocytes and increases efficacy of intravenously delivered oncolytic adenovirus. Hum Gene Ther 20 (2009) 975-988
4. Veronese F.M., and Pasut G. PEGylation, successful approach to drug delivery. Drug Discov Today 10 (2005) 1451-1458
5. Williams D.F. On the mechanisms of biocompatibility. Biomaterials 29 (2008) 2941-2953
6. Murciano J.C., Medinilla S., Eslin D., Atochina E., Cines D.B., and Muzykantov V.R. Prophylactic fibrinolysis through selective dissolution of nascent clots by tPA-carrying erythrocytes. Nat Biotechnol 21 (2003) 891-896
7. Zaitsev S., Danielyan K., Murciano J.C., Ganguly K., Krasik T., Taylor R.P., et al. Human complement receptor type 1-directed loading of tissue plasminogen activator on circulating erythrocytes for prophylactic fibrinolysis. Blood 108 (2006) 1895-1902
8. Ganguly K., Krasik T., Medinilla S., Bdeir K., Cines D.B., Muzykantov V.R., et al. Blood clearance and activity of erythrocyte coupled fibrinolytics. J Pharmacol Exp Ther 312 (2005) 1106-1113
9. Danielyan K., Ganguly K., Ding B.S., Atochin D., Zaitsev S., Murciano J.C., et al. Cerebrovascular thromboprophylaxis in mice by erythrocyte-coupled tissue-type plasminogen activator. Circulation 118 (2008) 1442-1449
10. Murciano J.C., Higazi A.A.R., Cines D.B., and Muzykantov V.R. Soluble urokinase receptor conjugated to carrier red blood cells binds latent pro-urokinase and alters its functional profile. J Control Release 139 (2009) 190-196
11. Discher D.E., Janmey P., and Wang Y. Tissue cells feel and respond to the stiffness of their substrate. Science 310 (2005) 1139-1143
12. Krieg M., Arboleda-Estudillo Y., Puech P.H., Kafer J., Graner F., Muller D.J., et al. Tensile forces govern germ-layer organization in zebrafish. Nat Cell Biol 10 (2008) 429-436
13. Luo D., and Saltzman W.B. Synthetic DNA delivery systems. Nat Biotechnol 18 (2000) 33-37
14. Hortin G.L., and Huang S.T. Surface-pegylated red cells as potential universal donor cells. Blood 88 S1 (1996) 181
15. Murad K.L., Mahany K.L., Kuypers F.A., Brugnara C., Eaton J.W., and Scott M.D. Structural and functional consequences of antigenic modulation of red blood cells with methoxypoly(ethylene glycol). Blood 93 (1999) 2121-2127
16. Armstrong J.K., Heiselman H.J., and Fisher T.C. Covalent binding of poly(ethylene glycol) (PEG) to the surface of red blood cells inhibits aggregation and reduces low-shear viscosity. Am J Hematol 56 (1997) 26-28
17. Scott M.D., Murad K.L., and Eaton J.W. The other blood substitute: antigenically inert erythrocytes. In: Winslow R.M., Vandegriff K.D., and Intaglietta M. (Eds). Advances in blood substitutes: industrial opportunities and medical challenges (1997), Birkhäuser, Boston 133-150
18. Bradley A.J., Murad K.L., Regan K.L., and Scott M.D. Biophysical consequences of linker chemistry and polymer size on stealth erythrocytes: size does matter. Biochim Biophys Acta 1561 (2002) 147-158
19. Neu B., Armstrong J.K., Fisher T.C., Bäumler H., and Meiselman H.J. Electrophoretic mobility of human red blood cells coated with poly(ethylene glycol). Biorheology 38 (2001) 389-403
20. Pierigè F., Serafini S., Rossi L., and Magnani M. Cell-based drug delivery. Adv Drug Deliv Rev 60 (2008) 286-295
21. Millan C.G., Marinero M.L.S., Castaneda A.Z., and Lanao J.M. Drug, enzyme and peptide delivery using erythrocytes as carriers. J Control Release 95 (2004) 27-49
22. Chambers E., and Mitragotri S. Long circulating nanoparticles via adhesion on red blood cells: mechanism and extended circulation. Exp Biol Med 232 (2007) 958-966
23. Kainthan R.K., Hester S.R., Levin E., Devine D.V., and Brooks D.E. In vitro biological evaluation of high molecular weight hyperbranched polyglycerols. Biomaterials 28 (2007) 4581-4590
24. Kainthan R.K., and Brooks D.E. In vivo biological evaluation of high molecular weight hyperbranched polyglycerols. Biomaterials 28 (2007) 4779-4787
25. Sunder A., Hanselmann R., Frey H., and Mulhaupt R. Controlled synthesis of hyperbranched polyglycerols by ring-opening multibranching polymerization. Macromolecules 32 (1999) 4240-4246
26. Kainthan R.K., Muliawan E.B., Hatzikiriakos S.G., and Brooks D.E. Synthesis, characterization, and viscoelastic properties of high molecular weight hyperbranched polyglycerols. Macromolecules 39 (2006) 7708-7717
27. Kizhakkedathu J.N., and Brooks D.E. Synthesis of poly(N,N-dimethylacrylamide) brushes from charged polymeric surfaces by aqueous ATRP: effect of surface initiator concentration. Macromolecules 36 (2003) 591-598
28. Walter H. Surface properties of cells reflected by partitioning: red blood cells as a model. In: Walter H, Brooks DE, Fisher D, editors. Partitioning in aqueous two-phase systems, Academic Press, Inc. (Orlando, Florida).
29. Bradley A.J., and Scott M.D. Separation and purification of methoxypoly(ethylene glycol) grafted red blood cells via two-phase partitioning. J Chromatogr B 807 (2004) 163-168
30. Sharp K.A., and Brooks D.E. Calculation of the electrophoretic mobility of a particle bearing bound polyelectrolyte using the non-linear Poissan-Boltzmann equation. Biophys J 47 (1985) 563-566
31. Buege J.A., and Aust S.D. Microsomal lipid peroxidation. Meth Enzymol 52 (1978) 302-310
32. Gutteridge J.M.C. Free radical damage to lipids, amino acids, carbohydrates, and nucleic acids determined by thiobarbituric acid reactivity. Int J Biochem 14 (1982) 649-653
33. Szebeni J., Winterbourn C., and Carrell R.W. Oxidative interactions between haemoglobin and membrane lipid. A liposome model. Bichem J 220 (1984) 685-692
34. Winterbourn C.C. Reaction with superoxide with hemoglobin. In: Greenwald R.A. (Ed). CRC handbook of methods for oxygen radical research (1985), CRC Press Inc, Boca Raton, Fla p.137-p.141
35. Roberts M.J., Bentley M.D., and Harris J.M. Chemistry for peptide and protein PEGylation. Adv Drug Deliv Rev 54 (2002) 459-476
36. Levine S., Levine M., and Brooks D.E. Theory of the electrokinetic behavior of human erythrocytes. Biophys J 42 (1983) 127-135
37. Jan K.M., and Chien S. Role of surface electric charge in red blood cell interactions. J Gen Physiol 61 (1973) 638-654
38. Hopewell J.W., Duncan R., Wilding D., and Chakrabarti K. Preclinical evaluation of the cardiotoxicity of PK2: a novel HPMA copolymer-doxorubicin-galactosamine conjugate antitumour agent. Hum Exp Toxicol 20 (2001) 461-470
39. Scott M.D., Meshnick S.R., Williams R.A., Chiu D.T.Y., Pan H.C., Lubin B.H., et al. Qinghaosu-mediated oxidation in normal and abnormal erythrocytes. J Lab Clin Med 114 (1989) 401-406
40. Kuypers F.A., Scott M.D., Schott M.A., Lubin B., and Chiu D.T. Use of ektacytometry to determine red cell susceptibility to oxidatative stress. J Lab Clin Med 116 (1990) 535-545
41. Scott M.D., Rouyer-Fessard P., Ba M.S., Lubin B.H., and Beuzard Y. α- and β-haemoglobin chain induced changes in normal erythrocyte deformability: comparison to β thalassemia intermedia and Hb H disease. Br J Haematol 80 (1992) 519-526
42. Zaitsev S., Spitzer D., Murciano J.-C., Ding B.-S., Tliba S., Kowalska M.A., et al. Targeting of a mutant plasminogen activator to circulating red blood cells for prophylactic fibrinolysis. J Pharmacol Exp Ther (2010) fast forward article (doi:10.1124/jpet.109.159194)