Molecular defects of the glycine 41 variants of alanine glyoxylate aminotransferase associated with primary hyperoxaluria type I

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 7, 2010, Pages 2896-2901

  Cellini, Barbara ^a   Montioli, Riccardo ^a   Paiardini, Alessandro ^b   Lorenzetto, Antonio ^a   Maset, Fabio ^c   Bellini, Tiziana ^d   Oppici, Elisa ^a   Voltattorni, Carla Borri ^a  

^a UNIVERSITY OF VERONA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF PADOVA   (Italy)

^d UNIVERSITY OF FERRARA   (Italy)

Author keywords

Dimer interface; Pathogenic variant; Protein aggregation; Pyridoxal 5 phosphate

Indexed keywords

ALANINE GLYOXYLATE AMINOTRANSFERASE; GLYCINE; METHIONINE; PROTEINASE K; TYROSINE;

ALLELE; ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DENATURATION; DIMERIZATION; DISSOCIATION CONSTANT; ENZYME BINDING; FLUORESCENCE; GENE MUTATION; IMMUNOREACTIVITY; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; OXALOSIS 1; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STRUCTURE; SIMULATION; THERMOSTABILITY; ULTRAVIOLET RADIATION;

ALANINE; CHROMATOGRAPHY, GEL; DIMERIZATION; GLYCINE; HUMANS; HYPEROXALURIA, PRIMARY; KINETICS; MASS SPECTROMETRY; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; NEPHELOMETRY AND TURBIDIMETRY; TRANSAMINASES;

EID: 77649267180     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0908565107     Document Type: Article

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