Investigation of NQO1 genetic polymorphism, NQO1 gene expression and PAH-DNA adducts in ESCC. A case-control study from Iran

Genetics and Molecular Research

Volumn 9, Issue 1, 2010, Pages 239-249

  Marjani, H A ^a   Biramijamal, F ^a   Rakhshani, N ^b   Hossein Nezhad, A ^a   Malekzadeh, R ^c  

^a NATIONAL INSTITUTE OF GENETIC ENGINEERING AND BIOTECHNOLOGY   (Iran)

^b IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Esophageal squamous cell carcinoma (ESCC); Northeast Iran; NQO1; PAH DNA adduct

Indexed keywords

POLYCYCLIC AROMATIC HYDROCARBON;

ADULT; ARTICLE; CASE CONTROL STUDY; CONTROLLED STUDY; DNA ADDUCT; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; ESOPHAGUS; FEMALE; GENE; GENE EXPRESSION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN TISSUE; IRAN; MAJOR CLINICAL STUDY; MALE; NQO1 GENE;

AGED; CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; DNA ADDUCTS; ESOPHAGEAL NEOPLASMS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC PREDISPOSITION TO DISEASE; HUMANS; IRAN; MALE; MIDDLE AGED; NAD(P)H DEHYDROGENASE (QUINONE); POLYCYCLIC HYDROCARBONS, AROMATIC; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 77649258069     PISSN: None     EISSN: 16765680     Source Type: Journal    
DOI: 10.4238/vol9-1gmr693     Document Type: Article

References (34)

1. Akpan V, Huang S, Lodovici M and Dolara P (2006). High levels of carcinogenic polycyclic aromatic hydrocarbons (PAH) in 20 brands of Chinese cigarettes. J. Appl. Toxicol. 26: 480-483.
2. Al-Saleh I, Arif J, El-Doush I, Al-Sanea N, et al. (2008). Carcinogen DNA adducts and the risk of colon cancer: casecontrol study. Biomarkers 13: 201-216.
3. Bartsch H (2000). Studies on biomarkers in cancer etiology and prevention: a summary and challenge of 20 years of interdisciplinary research. Mutat. Res. 462: 255-279.
4. Cleton-Jansen AM, van Eijk R, Lombaerts M, Schmidt MK, et al. (2008). ATBF1 and NQO1 as candidate targets for allelic loss at chromosome arm 16q in breast cancer: absence of somatic ATBF1 mutations and no role for the C609T NQO1 polymorphism. BMC Cancer 8: 105.
5. Crew KD, Gammon MD, Terry MB, Zhang FF, et al. (2007). Polymorphisms in nucleotide excision repair genes, polycyclic aromatic hydrocarbon-DNA adducts, and breast cancer risk. Cancer Epidemiol. Biomarkers Prev. 16: 2033-2041.
6. D'Errico A, Malats N, Vineis P and Boffetta P (1999). Review of studies of selected metabolic polymorphisms and cancer. IARC Sci. Publ. 148: 323-393.
7. Elovaara E, Mikkola J, Stockmann-Juvala H, Luukkanen L, et al. (2007). Polycyclic aromatic hydrocarbon (PAH) metabolizing enzyme activities in human lung, and their inducibility by exposure to naphthalene, phenanthrene, pyrene, chrysene, and benzo(a)pyrene as shown in the rat lung and liver. Arch. Toxicol. 81: 169-182.
8. Fagundes RB, Abnet CC, Strickland PT, Kamangar F, et al. (2006). Higher urine 1-hydroxy pyrene glucuronide (1-OHPG) is associated with tobacco smoke exposure and drinking mate in healthy subjects from Rio Grande do Sul, Brazil. BMC Cancer 6: 139.
9. Franco SS, Nardocci AC and Gunther WM (2008). PAH biomarkers for human health risk assessment: a review of the state-of-the-art. Cad. Saude Publica 24 (Suppl 4): s569-s580.
10. Hecht SS (2003). Tobacco carcinogens, their biomarkers and tobacco-induced cancer. Nat. Rev. Cancer 3: 733-744.
11. John K, Ragavan N, Pratt MM, Singh PB, et al. (2009). Quantification of phase I/II metabolizing enzyme gene expression and polycyclic aromatic hydrocarbon-DNA adduct levels in human prostate. Prostate 69: 505-519.
12. Kamangar F, Strickland PT, Pourshams A, Malekzadeh R, et al. (2005). High exposure to polycyclic aromatic hydrocarbons may contribute to high risk of esophageal cancer in northeastern Iran. Anticancer Res. 25: 425-428.
13. Kamangar F, Schantz MM, Abnet CC, Fagundes RB, et al. (2008). High levels of carcinogenic polycyclic aromatic hydrocarbons in mate drinks. Cancer Epidemiol. Biomarkers Prev. 17: 1262-1268.
14. Kolesar JM, Pritchard SC, Kerr KM, Kim K, et al. (2002). Evaluation of NQO1 gene expression and variant allele in human NSCLC tumors and matched normal lung tissue. Int. J. Oncol. 21: 1119-1124.
15. Lai TJ, Tsai YY, Cheng YW, Chiang CC, et al. (2006). An association between BPDE-like DNA adduct levels and P53 gene mutation in pterygium. Mol. Vis. 12: 1687-1691.
16. Long DJ, Waikel RL, Wang XJ, Roop DR, et al. (2001). NAD(P)H:quinone oxidoreductase 1 deficiency and increased susceptibility to 7,12-dimethylbenz[a] -anthracene-induced carcinogenesis in mouse skin. J. Natl. Cancer Inst. 93: 1166-1170.
17. Mahboubi E, Kmet J, Cook PJ, Day NE, et al. (1973). Oesophageal cancer studies in the Caspian Littoral of Iran: the Caspian cancer registry. Br. J. Cancer 28: 197-214.
18. McCarty KM, Santella RM, Steck SE, Cleveland RJ, et al. (2009). PAH-DNA adducts, cigarette smoking, GST polymorphisms, and breast cancer risk. Environ. Health Perspect. 117: 552-558.
19. Parkin DM, Bray F, Ferlay J and Pisani P (2001). Estimating the world cancer burden: Globocan 2000. Int. J. Cancer 94: 153-156.
20. Poirier MC (2004). Chemical-induced DNA damage and human cancer risk. Nat. Rev. Cancer 4: 630-637.
21. Rybicki BA, Rundle A, Savera AT, Sankey SS, et al. (2004). Polycyclic aromatic hydrocarbon-DNA adducts in prostate cancer. Cancer Res. 64: 8854-8859.
22. Sagiv SK, Gaudet MM, Eng SM, Abrahamson PE, et al. (2009). Polycyclic aromatic hydrocarbon-DNA adducts and survival among women with breast cancer. Environ. Res. 109: 287-291.
23. Sankaranarayanan K and Jaiswal AK (2004). Nrf3 negatively regulates antioxidant-response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene. J. Biol. Chem. 279: 50810-50817.
24. Santella RM, Gammon MD, Zhang YJ, Motykiewicz G, et al. (2000). Immunohistochemical analysis of polycyclic aromatic hydrocarbon-DNA adducts in breast tumor tissue. Cancer Lett. 154: 143-149.
25. Sarbia M, Bitzer M, Siegel D, Ross D, et al. (2003). Association between NAD(P)H:quinone oxidoreductase 1 (NQO1) inactivating C609T polymorphism and adenocarcinoma of the upper gastrointestinal tract. Int. J. Cancer 107: 381-386.
26. Sharp SY, Kelland LR, Valenti MR, Brunton LA, et al. (2000). Establishment of an isogenic human colon tumor model for NQO1 gene expression: application to investigate the role of DT-diaphorase in bioreductive drug activation in vitro and in vivo. Mol. Pharmacol. 58: 1146-1155.
27. Shimada T (2006). Xenobiotic-metabolizing enzymes involved in activation and detoxification of carcinogenic polycyclic aromatic hydrocarbons. Drug Metab. Pharmacokinet. 21: 257-276.
28. Siegel D, Anwar A, Winski SL, Kepa JK, et al. (2001). Rapid polyubiquitination and proteasomal degradation of a mutant form of NAD(P)H:quinone oxidoreductase 1. Mol. Pharmacol. 59: 263-268.
29. Tang D, Rundle A, Mooney L, Cho S, et al. (2003). Sulfotransferase 1A1 (SULT1A1) polymorphism, PAH-DNA adduct levels in breast tissue and breast cancer risk in a case-control study. Breast Cancer Res. Treat. 78: 217-222.
30. van Gijssel HE, Divi RL, Olivero OA, Roth MJ, et al. (2002). Semiquantitation of polycyclic aromatic hydrocarbon-DNA adducts in human esophagus by immunohistochemistry and the automated cellular imaging system. Cancer Epidemiol. Biomarkers Prev. 11: 1622-1629.
31. van Gijssel HE, Schild LJ, Watt DL, Roth MJ, et al. (2004). Polycyclic aromatic hydrocarbon-DNA adducts determined by semiquantitative immunohistochemistry in human esophageal biopsies taken in 1985. Mutat. Res. 547: 55-62.
32. Wang S, Chanock S, Tang D, Li Z, et al. (2008). Assessment of interactions between PAH exposure and genetic polymorphisms on PAH-DNA adducts in African American, Dominican, and Caucasian mothers and newborns. Cancer Epidemiol. Biomarkers Prev. 17: 405-413.
33. Zhang J, Schulz WA, Li Y, Wang R, et al. (2003a). Association of NAD(P)H: quinone oxidoreductase 1 (NQO1) C609T polymorphism with esophageal squamous cell carcinoma in a German Caucasian and a northern Chinese population. Carcinogenesis 24: 905-909.
34. Zhang JH, Li Y, Wang R, Geddert H, et al. (2003b). NQO1 C609T polymorphism associated with esophageal cancer and gastric cardiac carcinoma in North China. World J. Gastroenterol. 9: 1390-1393.