Construction and genetic selection of small transmembrane proteins that activate the human erythropoietin receptor

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 8, 2010, Pages 3447-3452

  Cammett, Tobin J ^a,c   Jun, Susan J ^a   Cohen, Emily B ^a   Barrera, Francisco N ^a   Engelman, Donald M ^a   DiMaio, Daniel ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE CANCER CENTER   (United States)

^c ALEXION PHARMACEUTICALS   (United States)

Author keywords

Bovine papilloma virus; E5 protein; Expression libraries; Protein engineering; Traptamers

Indexed keywords

AMINO ACID; ERYTHROPOIETIN RECEPTOR; MEMBRANE PROTEIN; PAPILLOMAVIRUS E5 PROTEIN; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; CELL DIFFERENTIATION; CELL TRANSFORMATION; GENE LIBRARY; GENETIC ANALYSIS; GENETICS; HUMAN; HUMAN CELL; IN VITRO STUDY; MODULATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; RETROVIRUS;

AMINO ACID SEQUENCE; CELL PROLIFERATION; HEMATOPOIETIC STEM CELLS; HUMANS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; MULTIPOTENT STEM CELLS; ONCOGENE PROTEINS, VIRAL; PEPTIDE LIBRARY; PROTEIN INTERACTION MAPPING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; RECEPTORS, ERYTHROPOIETIN; RETROVIRIDAE; SELECTION, GENETIC; SMALL MOLECULE LIBRARIES;

BOVINE PAPILLOMAVIRUS; MURINAE; PAPILLOMAVIRIDAE;

EID: 77649247830     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0915057107     Document Type: Article

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