Fucosylated glycan inhibition of human hepatocellular carcinoma cell migration through binding to chemokine receptors

Glycobiology

Volumn 20, Issue 2, 2009, Pages 215-223

  Wu, Li Hui ^a,b   Shi, Bi Zhi ^a   Zhao, Qian Lei ^b   Wu, Xing Zhong ^a  

^a FUDAN UNIVERSITY   (China)

^b THE SECOND AFFILIATED HOSPITAL AND YUYING CHILDREN S HOSPITAL OF WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Cell migration; Fucosylation; Interleukin 8

Indexed keywords

2' FUCOSYLLACTOSE; 3' FUCOSYLLACTOSE; ALPHA LEVO 1,2 FUCOSIDASE; ALPHA LEVO 1,3 FUCOSIDASE; ALPHA LEVO 1,4 FUCOSIDASE; ALPHA LEVO FUCOSIDASE; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CXCR2; F ACTIN; GLYCAN; GLYCOPEPTIDE; GLYCOPROTEIN; INTERLEUKIN 8; INTERLEUKIN 8 RECEPTOR; LACTOSE; LYMPHOTACTIN; MONOCYTE CHEMOTACTIC PROTEIN 1; PAPAIN; RETINOIC ACID; STROMAL CELL DERIVED FACTOR 1; TRYPSIN; UNCLASSIFIED DRUG; FUCOSE;

AFFINITY CHROMATOGRAPHY; ARTICLE; CHEMOTAXIS; CONTROLLED STUDY; FUCOSYLATION; GENE SILENCING; HUMAN; HUMAN CELL; INHIBITION KINETICS; LIVER CELL CARCINOMA; MIGRATION INHIBITION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN CARBOHYDRATE INTERACTION; PROTEIN FUNCTION; RECEPTOR BINDING; RNA INTERFERENCE; CELL MOTION; DRUG EFFECT; DRUG SCREENING; LIVER TUMOR; METABOLISM; PATHOLOGY; PROTEIN BINDING; STRUCTURE ACTIVITY RELATION;

CARCINOMA, HEPATOCELLULAR; CELL MOVEMENT; DRUG SCREENING ASSAYS, ANTITUMOR; FUCOSE; GLYCOPEPTIDES; GLYCOPROTEINS; HUMANS; LIVER NEOPLASMS; PROTEIN BINDING; RECEPTORS, CHEMOKINE; STRUCTURE-ACTIVITY RELATIONSHIP; TRETINOIN;

EID: 77649226211     PISSN: 09596658     EISSN: 14602423     Source Type: Journal    
DOI: 10.1093/glycob/cwp168     Document Type: Article

References (27)

1. Bone-Larson CL, Hogaboam CM, Evanhoff H, Strieter RM, Kunkel SL. 2001. IFN-gamma-inducible protein-10 (CXCL10) is hepatoprotective during acute liver injury through the induction of CXCR2 on hepatocytes. J Immunol. 167:7077-7083.
2. Candelier JJ, Mollicone R, Mennesson B, Coullin P, Oriol R. 2000. Expression of fucosyltransferases in skin, conjunctiva, and cornea during human development. Histochem Cell Biol. 114:113-124.
3. Dennis JW, Granovsky M, Warren CE. 1999. Protein glycosylation in development and disease. Bioessays. 21:412-421.
4. Domino SE, Zhang L, Gillespie PJ, Saunders TL, Lowe JB. 2001. Deficiency of reproductive tract alpha(1,2)fucosylated glycans and normal fertility in mice with targeted deletions of the FUT1 or FUT2 alpha(1,2)fucosyltransferase locus. Mol Cell Biol. 21:8336-8345.
5. Erdmann I, Scheidegger EP, Koch FK, Heinzerling L, Odermatt B, Burg G, Lowe JB, Kundig TM. 2002. Fucosyltransferase VII-deficient mice with defective E-, P-, and L-selectin ligands show impaired CD4+ and CD8+ T cell migration into the skin, but normal extravasation into visceral organs. J Immunol. 168:2139-2146.
6. Freund A, Chauveau C, Brouillet JP, Lucas A, Lacroix M, Licznar A, Vignon F, Lazennec G. 2003. IL-8 expression and its possible relationship with estrogen-receptor-negative status of breast cancer cells. Oncogene. 22:256-265.
7. Friedl P, Wolf K. 2003. Tumour-cell invasion and migration: Diversity and escape mechanisms. Nat Rev Cancer. 3:362-374.
8. Geng F, Shi BZ, Yuan YF, Wu XZ. 2004. The expression of core fucosylated E-cadherin in cancer cells and lung cancer patients: Prognostic implications. Cell Res. 14:423-433.
9. Guo HB, Lee I, Kamar M, Akiyama SK, Pierce M. 2002. Aberrant N-glycosylation of beta1 integrin causes reduced alpha5beta1 integrin clustering and stimulates cell migration. Cancer Res. 62:6837-6845.
10. Hogaboam CM, Bone-Larson CL, Steinhauser ML, Lukacs NW, Colletti LM, Simpson KJ, Strieter RM, Kunkel SL. 1999. Novel CXCR2-dependent liver regenerative qualities of ELR-containing CXC chemokines. Faseb J. 13:1565-1574.
11. Joshi-Barve S, Barve SS, Butt W, Klein J, McClain CJ. 2003. Inhibition of proteasome function leads to NF-kappaB-independent IL-8 expression in human hepatocytes. Hepatology. 38:1178-1187.
12. Larsen M, Tremblay ML, Yamada KM. 2003. Phosphatases in cell-matrix adhesion and migration. Nat Rev Mol Cell Biol. 4:700-711.
13. Mare L, Trinchera M. 2004. Suppression of beta 1,3galactosyltransferase beta 3Gal-T5 in cancer cells reduces sialyl-Lewis a and enhances poly N-acetyllactosamines and sialyl-Lewis x on O-glycans. Eur J Biochem. 271:186-194.
14. Miyoshi E, Noda K, Yamaguchi Y, Inoue S, Ikeda Y, Wang W, Ko JH, Uozumi N, Li W, Taniguchi N. 1999. The alpha1-6-fucosyltransferase gene and its biological significance. Biochim Biophys Acta. 1473:9-20.
15. Muller A, Homey B, Soto H, Ge N, Catron D, Buchanan ME, McClanahan T, Murphy E, Yuan W, Wagner SN, et al. 2001. Involvement of chemokine receptors in breast cancer metastasis. Nature. 410:50-56.
16. Ohyama C, Tsuboi S, Fukuda M. 1999. Dual roles of sialyl Lewis X oligosaccharides in tumor metastasis and rejection by natural killer cells. Embo J. 18:1516-1525.
17. Otake Y, Fujimoto I, Tanaka F, Nakagawa T, Ikeda T, Menon KK, Hase S, Wada H, Ikenaka K. 2001. Isolation and characterization of an N-linked oligosaccharide that is significantly increased in sera from patients with non-small cell lung cancer. J Biochem. 129:537-542.
18. Popescu O, Checiu I, Gherghel P, Simon Z, Misevic GN. 2003. Quantitative and qualitative approach of glycan-glycan interactions in marine sponges. Biochimie. 85:181-188.
19. Raman D, Baugher PJ, Thu YM, Richmond A. 2007. Role of chemokines in tumor growth. Cancer Lett. 256:137-165.
20. Shields JD, Fleury ME, Yong C, Tomei AA, Randolph GJ, Swartz MA. 2007. Autologous chemotaxis as a mechanism of tumor cell homing to lymphatics via interstitial flow and autocrine CCR7 signaling. Cancer Cell. 11:526-538.
21. Wang XC, Gu JG, Ihara H, Miyoshi E, Honke K, Taniguchi N. 2006. Core fucosylation regulates epidermal growth factor receptor-mediated intracellular signaling. J Biol Chem. 281:2572-2577.
22. Wang XC, Inoue S, Gu JG, Miyoshi E, Noda K, Li WZ, Mizuno-Horikawa Y, Nakano M, Asahi M, Takahashi M, et al. 2005. Dysregulation of TGF-beta 1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice. Proc Natl Acad Sci USA. 102: 15791-15796.
23. Wu XZ, Chen YF. 2002. Fucosylated oligosaccharides in migration of hepatoma cells. Prog Biochem Biophys. 9:933-937.
24. Wu XZ, Li Z, Shi BZ, Hu P. 2005. Inhibitory effects of N-(4-hydrophenyl) retinamide on liver cancer and malignant melanoma cells World J Gastroenterol. 11:5763-5769.
25. Wu XZ, Lu H, Chen YF, Zha XL. 2003. Fucosylated oligosaccharides in hepatoma cell migration inhibition by N(4-hydrophenyl) retinamide. Fudan Univ J Med Sci. 30:430-433.
26. WU XZ, SHI PC, HU P, CHEN Y, DING SS. 2006. N-all-trans-retinoyl-L-proline inhibits metastatic potential of hepatocellular carcinoma cells. Cell Biol Int. 30:672-680.
27. Zhao YY, Itoh S, Wang XC, Isaji T, Miyoshi E, Kariya Y, Miyazaki K, Kawasaki N, Taniguchi N, Gu JG. 2006. Deletion of core fucosylation on alpha 3 beta 1 integrin down-regulates its functions. J Biol Chem. 281:38343-38350.