Invasive carcinomas may arise in colorectal adenomas with high-grade dysplasia and with carcinoma in situ

International Journal of Clinical and Experimental Medicine

Volumn 3, Issue 1, 2010, Pages 41-47

  Rubio, Carlos A ^a   Delinassios, John G ^b  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b International Institute of Anticancer Research   (Greece)

Author keywords

Carcinoma in situ; Colon adenomas; High grade dysplasia; Submucosal invasion

Indexed keywords

KI 67 ANTIGEN; TUMOR MARKER;

ANTIGEN EXPRESSION; ARTICLE; CANCER CELL; CANCER GROWTH; CANCER INVASION; CARCINOMA IN SITU; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRUCTURE; COLORECTAL ADENOMA; COLORECTAL CARCINOMA; DNA CONTENT; DYSPLASIA; FEULGEN STAINING; HIGH GRADE DYSPLASIA; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INVASIVE CARCINOMA;

EID: 77649221962     PISSN: None     EISSN: 19405901     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Morson BC, Whiteway JE, Jones EA, Macrae FA and Williams CB: Histopathology and prognosis of malignant colorectal polyps treated by endoscopic polypectomy. Gut 1984;25:437-44
2. Ferlay J, Bray F, Pisani P et al. GLOBOCAN 2002 Cancr incidence. Mortality and prevalence Worldwide. IARC Cancer-Base No.5, verion 2.0. Lyon: IARC-Press, 2004.
3. Khatibzadeh N, Ziaee SA, Rahbar N, Molanie S, Arefian L and Fanaie SA: The indirect role of site distribution in high-grade dysplasia in adenomatous colorectal polyps. J Cancer Res Ther 2005;1:204-207
4. Cole BF, Baron JA, Sandler RS, Haile RW, Ahnen DJ, Bresalier RS, McKeown-Eyssen G, Summers RW, Rothstein RI, Burke CA, Snover DC, Church TR, Allen JI, Robertson DJ, Beck GJ, Bond JH, Byers T, Mandel JS, Mott LA, Pearson LH, Barry EL, Rees JR, Marcon N, Saibil F, Ueland PM, Greenberg ER and Polyp Prevention Study Group: Folic acid for the prevention of colorectal adenomas: a randomized clinical trial. JAMA. 2007;297:2351-2359.
5. Parra-Blanco A, Gimeno-García AZ, Nicolás-Pérez D, García C, Medina C, Díaz-Flores L, Grosso B, Jiménez A and Quintero E: Risk for high-grade dysplasia or invasive carcinoma in colorectal flat adenomas in a Spanish population. Gastroenterol Hepatol 2006;29:602-609
6. Giuliani A, Caporale A, Corona M, Ricciardulli T, Di Bari M, Demoro M, Scarpini M and Angelico F: Large size, villous content and distal location are associated with severe dysplasia in colorectal adenomas. Anticancer Res 2006;26:3717-3722
7. Sheridan TB, Fenton H, Lewin MR, Burkart AL, Iacobuzio-Donahue CA and Frankel W: Montgomery E. Sessile serrated adenomas with low- and high-grade dysplasia and early carcinomas: an immunohistochemical study of serrated lesions "caught in the act". Am J Clin Pathol 2006;126: 564-571
8. Chandra A, Sheikh AA, Cerar A, Talbot IC. Clinicopathological aspects of colorectal serrated adenomas. World J Gastroenterol 2006;12:2770-2772
9. Ackermann S, Gehrsitz C, Mehlhorn G and Beckmann MW: Management and course of histologically verified cervical carcinoma in situ during pregnancy. Acta Obstet Gynecol Scand 2006;85:1134-1137
10. Gonzalez RJ, Buzdar AU, Fraser Symmans W, Yen TW, Broglio KR, Lucci A, Esteva FJ, Yin G and Kuerer HM: Novel clinical trial designs for treatment of ductal carcinoma in situ of the breast with trastuzumab (herceptin). Breast J 2007;13:72-75
11. Ondo AL, Mings SM, Pestak RM and Shanler SD: Topical combination therapy for cutaneous squamous cell carcinoma in situ with 5-fluorouracil cream and imiquimod cream in patients who have failed topical monotherapy. J Am Acad Dermatol 2006:55:1092-1094
12. Raju RR, Goldblum JR and Hart WR: Pagetoid squamous cell carcinoma in situ (pagetoid Bowen's disease) of the external genitalia. Int J Gynecol Pathol 2003;22:127-135
13. Wilkin TJ, Palmer S, Brudney KF, Chiasson MA and Wright TC: Anal intraepithelial neoplasia in heterosexual and homosexual HIV-positive men with access to antiretroviral therapy. J Infect Dis 2004;190:1685-1691
14. Abe K, Suda K, Arakawa A, Yamasaki S, Sonoue H, Mitani K and Nobukawa B: Different patterns of p16INK4A and p53 protein expressions in intraductal papillary-mucinous neoplasms and pancreatic intraepithelial neoplasia. Pancreas 2007;34:85-91
15. Yin H, He Q, Li T and Leong AS: Cytokeratin 20 and Ki-67 to distinguish carcinoma in situ from flat non-neoplastic urothelium. Appl Immunohistochem Mol Morphol 2006;14:260-265
16. Snijders PJ, Breuer RH, Sutedja TG, Egging M, Voorhorst FJ, Steenbergen RD, van der Linden HC, Risse EK, Berkhof J, de Vries EG, van der Zee AG, Postmus PE, Meijer CJ and Smit EF: Elevated hTERT mRNA levels: A potential determinant of bronchial squamous cell carcinoma (in situ). Int J Cancer 109:412-417, 2004.
17. Morson BC: The polyp-cancer sequence in the large bowel. Proc Roy Soc Med 1974;67:1-7. 1962;179:316-21.
18. Morson BC and Konishi F: Contribution of the pathologist to the radiology and management of colorectal polyps. Gastrointest Radiol 1982;7: 275-281
19. Yamaji Y, Mitsushima T, Ikuma H, Watabe H, Okamoto M, Kawabe T, Wada R, Doi H and Omata M: Incidence and recurrence rates of colorectal adenomas estimated by annually repeated colonoscopies on asymptomatic Japanese. Gut 2004;53:568-572
20. Yoshida R, Kiyozuka Y, Ichiyoshi H, Senzaki H, Takada H, Hioki K and Tsubura A: Change in telomerase activity during human colorectal carcinogenesis. Anticancer Res 1999;19:2167-72
21. Schlemper RJ, Riddell RH, Kato Y, Borchard F, Cooper HS, Dawsey SM, Dixon MF, Fenoglio-Preiser CM, Fléjou JF, Geboes K, Hattori T, Hirota T, Itabashi M, Iwafuchi M, Iwashita A, Kim YI, Kirchner T, Klimpfinger M, Koike M, Lauwers GY, Lewin KJ, Oberhuber G, Offner F, Price AB, Rubio CA, Shimizu M, Shimoda T, Sipponen P, Solcia E, Stolte M, Watanabe H and Yamabe H: The Vienna classification of gastrointestinal epithelial neoplasia. Gut 2000;47:251-255
22. Rubio CA, Nesi G, Messerini L, Zampi GC, Mandai K, Itabashi M and Takubo K: The Vienna classification applied to colorectal adenomas. J Gastroenterol Hepatol 2006;21:1697-1703
23. Morson BC, Sobin LH, Grundmann E, Johansen A, Nagayo T and Serck-Hanssen A: Precancerous conditions and epithelial dysplasia in the stomach. J Clin Pathol 1980;33:711-721.
24. Nagayo T: Dysplasia of the gastric mucosa and its elation to the pecanceous state. Gann 1981;72:813-823
25. Fenoglio-Preiser C, Lantz P, Lindstrom M, Davies M and Rilke F: Gastrointestinal Pathology. An Atlas and Text. Raven Press, New York, 1989, Second Edition, pp 909-1068.
26. Miyaki M, Iijima T, Yamaguchi T, Hishima T, Tamura K, Utsunomiya J and Mori T: Germline mutations of the MYH gene in Japanese patients with multiple colorectal adenomas. Mutat Res 2005;578:430-433
27. Fujii S, Fujimori T, Kawamata H, Takeda J, Kitajima K, Omotehara F, Kaihara T, Kusaka T, Ichikawa K, Ohkura Y, Ono Y, Imura J, Yamaoka S, Sakamoto C, Ueda Y and Chiba T: Development of colonic neoplasia in p53 deficient mice with experimental colitis induced by dextran sulphate sodium. Gut 2004;53:710-716.
28. Sugai T, Habano W, Uesugi N, Jiao YF, Nakamura S, Sato K, Chiba T and Ishii M: Molecular validation of the modified Vienna classification of colorectal tumors. J Mol Diagn 2002;4:191-200.
29. Rubio CA: Qualitative DNA differences between two structurally different lesions: high-grade dysplasia and carcinoma in situ in colorectal adenomas. Anticancer Res 2007;27:2881-2885.
30. Rubio CA: Difference in cell proliferation between two structurally different lesions in colorectal adenomas: high-grade dysplasia and carcinoma in situ. Anticancer Res 2007;27:4321-4324.
31. Lawrie L, Curran S, McLeod H, Fothergill J and Murray G: Application of laser capture microdissection and proteomics in colon cancer. Mol Path 2001;54:253-258.