Cost-benefit analysis of supplemented very low-protein diet versus dialysis in elderly CKD5 patients

Nephrology Dialysis Transplantation

Volumn 25, Issue 3, 2010, Pages 907-913

  Scalone, Luciana ^a,b   Borghetti, Francesca ^a,b   Brunori, Giuliano ^c   Viola, Battista Fabio ^c   Brancati, Barbara ^d   Sottini, Laura ^c   Mantovani, Lorenzo Giovanni ^b,d   Cancarini, Giovanni ^c  

^a UNIVERSITY OF MILAN   (Italy)

^b CHARTA Foundation   (Italy)

^c UNIVERSITY OF BRESCIA   (Italy)

^d UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Cost benefit; Dialysis; Elderly; End stage renal disease; Low protein diet

Indexed keywords

ALENDRONIC ACID; AMINO ACID; ANTACID AGENT; ANTIARRHYTHMIC AGENT; ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT; ANTITHROMBOCYTIC AGENT; CALCITRIOL; CALCIUM CARBONATE; CARNITINE; ERYTHROPOIETIN; KETONE DERIVATIVE; PHOSPHATE BINDING AGENT; SEVELAMER; STOMACH SECRETION INHIBITOR;

AGED; ARTICLE; CHRONIC KIDNEY DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COST BENEFIT ANALYSIS; DRUG COST; ECONOMIC EVALUATION; ENERGY CONSUMPTION; FEMALE; FOLLOW UP; GLOMERULUS FILTRATION RATE; HEALTH CARE COST; HEMODIALYSIS; HOSPITALIZATION; HUMAN; IRON THERAPY; LABORATORY TEST; MALE; MORBIDITY; MORTALITY; PRIORITY JOURNAL; PROTEIN RESTRICTION; QUANTITATIVE ANALYSIS; RANDOMIZED CONTROLLED TRIAL; SAFETY; TRAVEL;

AGED; AGED, 80 AND OVER; CHRONIC DISEASE; COST-BENEFIT ANALYSIS; DIET, PROTEIN-RESTRICTED; FEMALE; HUMANS; ITALY; KIDNEY DISEASES; MALE; NATIONAL HEALTH PROGRAMS; RENAL DIALYSIS; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

EID: 77649205055     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfp572     Document Type: Article

References (25)

1. United States Renal Data System. USRDS 2008 Annual Data Report: Atlas of Chronic Kidney Disease and End-Stage Renal Disease in the United States. Bethesda, MA: National Institutes of Health, National Institute of Diabetes and Kidney Diseases 2008
2. Pontoriero G, Pozzoni P, Del Vecchio L, et al. International study of Health Care Organization and financing for renal replacement therapy in Italy: an evolving reality. Int J Health Care Finance Econ 2007; 7: 201-215
3. Lee H, Manns B, Taub K, et al. Cost analysis of ongoing care of patients with end stage renal disease: the impact of dialysis modality and dialysis access. Am J Kidney Dis 2002; 40: 611-622
4. Zamboli P, De Nicola L, Minutolo L, et al. Lo scompenso cardiaco nel paziente con insufficienza renale cronica: dall'epidemiologia alla terapia. G Ital Nefrol 2007; 24: 574-583
5. Grassmann A, Gioberge S, Moeller S, et al. ESRD patients in 2004: global overview of patients numbers, treatment modalities and associated trends. Nephrol Dial Transplant 2005; 20: 2587-2593
6. Bakewell AB, Higgins RM, Edmunds ME. Quality of life in peritoneal dialysis patients: decline over time and association with clinical outcomes. Kidney Int 2002; 61: 239-248
7. Gorodetskaya I, Zenios S, McCulloch CE, et al. Health-related quality of life and estimates of utility in chronic kidney disease. Kidney Int 2002; 61: 239-248
8. Kazmi WH, Gilbetson DT, Obrandor GT, et al. Effect of comorbidity on the increased mortality associated with early initiation of dialysis. Am J Kidney Dis 2005; 46: 887-896
9. European Best Practice Guidelines Expert Group on Hemodialysis, European Renal Association. Section I. Measurement of renal function, when to refer and when to start dialysis. Nephrol Dial Transplant 2002; 17: S7-S15
10. Traynor JP, Simpson K, Geddes CC, et al. Early initiation of dialysis fails to prolong survival in patients with end-stage renal failure. Ne-phrol Dial Transplant 2004; 19: 1009
11. Aparicio M, Chauveau P, De Pregigout V, et al. Nutrition and outcome on renal replacement therapy of patients with chronic renal failure treated by a supplemented very low protein diet. J Am Soc Nephrol 2000; 11: 708-716
12. Teschan PE, Beck GJ, Dwyer JT, et al. Effect of a keto-acid-supple-mented very low protein diet on the progression of advanced renal disease: a reanalysis of the MDRD feasibility study. Clin Nephrol 1998; 50: 273-283
13. Walser M, Hill S. Can renal replacement be deferred by a supplemented very low protein diet? J Am Soc Nephrol 1999; 10: 110-116
14. Beddhu S, Samore MH, Roberts MS, et al. Impact of timing of initiation of dialysis on mortality. J Am Soc Nephrol 2003; 14: 2305-2312
15. Brunori G, Viola BF, Parrinello G, et al. Efficacy and safety of a very-low-protein diet when postponing dialysis in the elderly: a prospective randomized multicenter controlled study. Am J Kidney Dis 2007; 49: 569-580
16. Drummond MF, Stoddart GL, Torrance GW. Methods for Economic Evaluation of Health Care Programmes. Oxford: Oxford University Press; 1997
17. Lombardy Regional Decree VII/15324. Tariffe delle prestazioni ospe-daliere in regime di ricovero in vigore dalle dimissioni del 1/1/2004 (CMS-DRG Grouper V19.0) November 28, 2003
18. Lombardy Region Resolution N. VIII/ 5743. Le Tariffe delle presta-zioni sanitarie October 31, 2007
19. Fuel Prices, Ministry of Economic Development: available at URL http://www.sviluppoeconomico.gov.it/, visited on February 2008
20. Reimbursement Prices and Market: available at URL http://www. agenziafarmaco.it, visited in February 2008
21. Pacheco A, Saffie A, Torres R, et al. Cost/utility study of peritoneal dialysis and hemodialysis in Chile. Perit Dial Int 2007; 27: 359-363
22. Kaitelidou D, Ziroyanis PN, Maniadakis N, et al. Economic evaluation of hemodialysis: implications for technology assessment in Greece. Int J Technol Assess Health Care 2005; 21: 40-46
23. Gudex CM. Health related quality of life in end-stage renal failure. Qual Life Res 1995; 4: 359-366
24. Brunori G, Bandera A, Valente F, et al. Vascular access for dialysis in elderly: AVF versus permanent CVC. G Ital Nefrol 2008; 25: 614-618
25. Ekbal NJ, Swift PA, Chalisey A, et al. Hemodialysis access-related survival and morbidity in an elderly population in South West Thames, UK. Hemodial Int 2008; 12: S15-S19