Proinflammatory gene expression at chronic periodontitis and peri-implantitis sites in patients with or without type 2 diabetes

Journal of Periodontology

Volumn 81, Issue 1, 2010, Pages 99-108

  Venza, Isabella ^a   Visalli, Maria ^a   Cucinotta, Maria ^a   De Grazia, Giuseppina ^a   Teti, Diana ^a   Venza, Mario ^a  

^a UNIVERSITY OF MESSINA   (Italy)

Author keywords

Chemokine; Chronic periodontitis; Cytokines; Diabetes mellitus; Receptors

Indexed keywords

AUTACOID; CHEMOKINE RECEPTOR CCR; CHEMOKINE RECEPTOR CXCR; INTERLEUKIN DERIVATIVE; RNA; TUMOR NECROSIS FACTOR ALPHA;

AGED; ANALYSIS OF VARIANCE; ARTICLE; CASE CONTROL STUDY; CHRONIC PERIODONTITIS; CLASSIFICATION; COMPARATIVE STUDY; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; IMMUNOLOGY; MALE; METABOLISM; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; NONPARAMETRIC TEST; REFERENCE VALUE; TOOTH IMPLANTATION;

AGED; ANALYSIS OF VARIANCE; CASE-CONTROL STUDIES; CHRONIC PERIODONTITIS; DENTAL IMPLANTS; DIABETES MELLITUS, TYPE 2; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKINS; MALE; MIDDLE AGED; RECEPTORS, CCR; RECEPTORS, CXCR; REFERENCE VALUES; RNA; STATISTICS, NONPARAMETRIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77649194631     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2009.090358     Document Type: Article

References (50)

1. Iacopino AM. Periodontitis and diabetes interrelationships: Role of inflammation. Ann Periodontol 2001;6: 125-137.
2. Grossi SG, Genco RJ. Periodontal disease and diabetes mellitus: A two-way relationship. Ann Periodontol 1998;3:51-61.
3. Southerland JH, Taylor GW, Offenbacher S. Diabetes and periodontal infection: Making the connection. Clinical Diabetes 2005;23:171-178.
4. Mealey BL. Periodontal disease and diabetes. A twoway street. J Am Dent Assoc 2006;137(Suppl.):26S-31S.
5. Ryan ME, Carnu O, Kamer A. The influence of diabetes on the periodontal tissues. J Am Dent Assoc 2003;134:34S-40S.
6. Salvi GE, Beck JD, Offenbacher S. PGE2, IL-1beta, and TNF-alpha responses in diabetics as modifiers of periodontal disease expression. Ann Periodontol 1998;3:40-50.
7. Nishimura F, Takahashi K, Kurihara M, Takashiba S, Murayama Y. Periodontal disease as a complication of diabetes mellitus. Ann Periodontol 1998;3:20-29.
8. Mealey BL, Oates TW. Diabetes mellitus and periodontal diseases. J Periodontol 2006;77:1289-1303.
9. Graves DT, Liu R, Alikahani M, Al-Mashat H, Trackman PC. Diabetes-enhanced inflammation and apoptosisimpact on periodontal pathology. J Dent Res 2006;85: 15-21.
10. Schulze A, Busse M. Periodontal diseases in diabetics: Relationship, prevention, and treatment. CSMI 2008;1:1-4.
11. Engebretson SP, Vossughi F, Hey-Hadavi J, Emingil G, Grbic JT. The influence of diabetes on gingival crevicular fluid beta-glucuronidase and interleukin-8. J Clin Periodontol 2006;33:784-790.
12. Kardešler L, Buduneli N, Biyikoǧlu B, Çetinkalp S, Kütükçüler N. Gingival crevicular fluid PGE2, IL-1beta, t-PA, PAI-2 levels in type 2 diabetes and relationship with periodontal disease. Clin Biochem 2008;41:863-868.
13. Gursoy UK, Marakoglu I, Oztop AY. Relationship between neutrophil functions and severity of periodontitis in obese and/or type 2 diabetic chronic periodontitis patients. Quintessence Int 2008;39:485-489.
14. Nishimura F, Soga Y, Iwamoto Y, Kudo C, Murayama Y. Periodontal disease as a part of the insulin resistance syndrome in diabetic patients. J Int Acad Periodontol 2005;7:16-20.
15. Venza M, Visalli M, Cucinotta M, Cicciù D, Passi P, Teti D. Salivary histamine level as a predictor of periodontal disease in type 2 diabetic and non-diabetic subjects. J Periodontol 2006;77:1564-1571.
16. Cole CM, Sundararaj KP, Leite RS, et al. A trend of increase in periodontal interleukin-6 expression across patients with neither diabetes nor periodontal disease, patients with periodontal disease alone, and patients with both diseases. J Periodontal Res 2008; 43:717-722.
17. Duarte PM, Neto JB, Casati MZ, Sallum EA, Nociti FH Jr. Diabetes modulates gene expression in the gingival tissues of patients with chronic periodontitis. Oral Dis 2007;13:594-599.
18. Duarte PM, de Oliveira MC, Tambeli CH, Parada CA, Casati MZ, Nociti FH Jr. Overexpression of interleukin- 1beta and interleukin-6 may play an important role in periodontal breakdown in type 2 diabetic patients. J Periodontal Res 2007;42:377-381.
19. Nicoletti R, Venza I, Ceci G, Visalli M, Teti D, Reibaldi A. Vitreous polyamines spermidine, putrescine, and spermine in human proliferative disorders of the retina. Br J Ophthalmol 2003;87:1038-1042.
20. Mombelli A, van Oosten MA, Schurch E Jr., Land NP. The microbiota associated with successful or failing osseointegrated titanium implants. Oral Microbiol Immunol 1987;2:145-151.
21. Apse P, Ellen RP, Overall CM, Zarb GA. Microbiota and crevicular fluid collagenase activity in the osseointegrated dental implant sulcus: A comparison of sites in edentulous and partially edentulous patients. J Periodontal Res 1989;24:96-105.
22. Armitage GC. Development of a classification system for periodontal diseases and conditions. Ann Periodontol 1999;4:1-6.
23. Irwin CR, Myrillas TT. The role of IL-6 in the pathogenesis of periodontal disease. Oral Dis 1998;4: 43-47.
24. Duarte PM, de Mendoncxa AC, Máximo MB, Santos VR, Bastos MF, Nociti Jú nior FH. Differential cytokine expressions affect the severity of peri-implant disease. Clin Oral Implants Res 2009;20:514-520
25. Silva N, Dutzan N, Hernandez M, et al. Characterization of progressive periodontal lesions in chronic periodontitis patients: Levels of chemokines, cytokines, matrix metalloproteinase-13, periodontal pathogens and inflammatory cells. J Clin Periodontol 2008;35: 206-214.
26. Bastos MF, Lima JA, Vieira PM, Mestnik MJ, Faveri M, Duarte PM. TNF-alpha and IL-4 levels in generalized aggressive periodontitis subjects. Oral Diseases 2009; 15:82-87.
27. Bostanci N, Emingil G, Afacan B, et al. Tumor necrosis factor-alpha-converting enzyme (TACE) levels in periodontal diseases. J Dent Res 2008;87:273-277.
28. Havemose-Poulsen A, Sørensen LK, Stoltze K, Bendtzen K, Holmstrup P. Cytokine profiles in peripheral blood and whole blood cell cultures associated with aggres-sive periodontitis, juvenile idiopathic arthritis, and rheumatoid arthritis. J Periodontol 2005;76:2276-2285.
29. Lee E, Yang YH, Ho YP, Ho KY, Tsai CC. Potential role of vascular endothelial growth factor, interleukin- 8 and monocyte chemoattractant protein-1 in periodontal diseases. Kaohsiung J Med Sci 2003;19: 406-415.
30. Lin SJ, Chen YL, Kuo MY, Li CL, Lu HK. Measurement of gp130 cytokines oncostatin M and IL-6 in gingival crevicular fluid of patients with chronic periodontitis. Cytokine 2005;30:160-167.
31. Ramseier CA, Kinney JS, Herr AE, et al. Identification of pathogen and host-response markers correlated with periodontal disease. J Periodontol. 2009;80:436-446.
32. Murata M, Tatsumi J, Kato Y, et al. Osteocalcin, deoxypyridinoline and interleukin-1beta in periimplant crevicular fluid of patients with peri-implantitis. Clin Oral Implants Res. 2002;13:637-643.
33. McFarlane CG, Reynolds JJ, Meikle MC. The release of interleukin-1 beta, tumor necrosis factor-alpha and interferon-gamma by cultured peripheral blood mononuclear cells from patients with periodontitis. J Periodontal Res 1990;25:207-214.
34. Daǧ A, Firat ET, Arikan Š, Kadiroǧlu AK, Kaplan A. The effect of periodontal therapy on serum TNF-alpha and HbA1c levels in type 2 diabetic patients. Aust Dent J 2009;54:17-22.
35. Kurtiš B, Tüter G, Serdar M, et al. Gingival crevicular fluid levels of monocyte chemoattactant protein-1 and tumor necrosis factor-alpha in patients with chronic and aggressive periodontitis. J Periodontol 2005;76: 1849-1855.
36. Konttinen YT, Lappalainen R, Laine P, Kitti U, Santavirta S, Teronen O. Immunohistochemical evaluation of inflammatory mediators in failing implants. Int J Periodontics Restorative Dent 2006;26:135-141.
37. Lalla E, Lamster IB, Schmidt AM. Enhanced interaction of advanced glycation end products with their cellular receptor RAGE: Implications for the pathogenesis of accelerated periodontal disease in diabetes. Ann Periodontol 1998;3:13-19.
38. Lalla E, Lamster IB, Feit M, et al. Blockade of RAGE suppresses periodontitis-associated bone loss in diabetic mice. J Clin Invest 2000;105:1117-1124.
39. Shlossman M. Diabetes mellitus and periodontal disease - A current perspective. Compendium 1994;15: 1018, 1020-1024 passim; quiz 1032.
40. Jones SA. Directing transition from innate to acquired immunity: Defining a role for IL-6. J Immunol 2005; 175:3463-3468.
41. Cutler CW, Machen RL, Jotwani R, Iacopino AM. Heightened gingival inflammation and attachment loss in type 2 diabetics with hyperlipidemia. J Periodontol 1999;70:1313-1321.
42. Kurtis B, Develioglu H, Taner IL, Balos K, Tekin IO. IL- 6 levels in gingival crevicular fluid (GCF) from patients with non-insulin dependent diabetes mellitus (NIDDM), adult periodontitis and healthy subjects. J Oral Sci 1999;41:163-167.
43. Lamster IB, Oshrain RL, Gordon JM. Enzyme activity in human gingival crevicular fluid: Considerations in data reporting based on analysis of individual crevicular sites. J Clin Periodontol. 1986;13:799-804.
44. Tsai CC, Ho YP, Chen CC. Levels of interleukin-1 beta and interleukin-8 in gingival crevicular fluids in adult periodontitis. J Periodontol 1995;66:852-859.
45. Yamalik N, Caǧlayan F, Kilincx K, Kilincx A, Tümer C. The importance of data presentation regarding gingival crevicular fluid myeloperoxidase and elastase-like activity in periodontal disease and health status. J Periodontol. 2000;71:460-467.
46. Garlet GP, Martins W Jr., Ferreira BR, Milanezi CM, Silva JS. Patterns of chemokines and chemokine receptors expression in different forms of human periodontal disease. J Periodontal Res 2003;38:210-217.
47. Fokkema SJ, Loos BG, van der Velden U. Monocytederived RANTES is intrinsically elevated in periodontal disease while MCP-1 levels are related to inflammation and are inversely correlated with IL-12 levels. Clin Exp Immunol 2003;131:477-483.
48. Colotta F, Borre A, Wang JM, et al. Expression of a monocyte chemotactic cytokine by human mononuclear phagocytes. J Immunol 1992;148:760-765.
49. Graves DT. The potential role of chemokines and inflammatory cytokines in periodontal disease progression. Clin Infect Dis 1999;28:482-490.
50. Sakallioǧlu EE, Ayas B, Lütfioǧlu M, Kelesx GC, Açikgöz G, Firatli E. Gingival levels of monocyte chemoattractant protein-1 (MCP-1) in diabetes mellitus and periodontitis: An experimental study in rats. Clin Oral Investig. 2008;12:83-89.