Activation of human neutrophils by titanium dioxide (TiO2) nanoparticles

Toxicology in Vitro

Volumn 24, Issue 3, 2010, Pages 1002-1008

  Goncalves D M ^a   Chiasson, S ^a   Girard, D ^a  

^a UNIVERSITÉ LAVAL   (Canada)

Author keywords

Cytokines; Human; Nanoparticles; Neutrophils; Signal transduction; TiO2

Indexed keywords

INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NANOPARTICLE; TITANIUM DIOXIDE;

APOPTOSIS; ARTICLE; CELL DEATH; CELL STRUCTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKOCYTE ACTIVATION;

APOPTOSIS; CELL SEPARATION; CHEMOKINES; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; INTERLEUKIN-4; INTERLEUKIN-8; NANOPARTICLES; NEUTROPHIL ACTIVATION; NEUTROPHILS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEOME; TITANIUM; TYROSINE;

EID: 77649191863     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2009.12.007     Document Type: Article

References (45)

1. Akgul C., Moulding D.A., and Edwards S.W. Molecular control of neutrophil apoptosis. FEBS Letters 487 (2001) 318-322
2. Alam R., Kumar D., Anderson-Walters D., and Forsythe P.A. Macrophage inflammatory protein-1 alpha and monocyte chemoattractant peptide-1 elicit immediate and late cutaneous reactions and activate murine mast cells in vivo. Journal of Immunology 152 (1994) 1298-1303
3. Arys A., Philippart C., Dourov N., He Y., Le Q.T., and Pireaux J.J. Analysis of titanium dental implants after failure of osseointegration: combined histological, electron microscopy, and X-ray photoelectron spectroscopy approach. Journal of Biomedical Materials Research 43 (1998) 300-312
4. Bennett P.A., Dixon R.J., and Kellie S. The phosphotyrosine phosphatase inhibitor vanadyl hydroperoxide induces morphological alterations, cytoskeletal rearrangements and increased adhesiveness in rat neutrophil leucocytes. Journal of Cell Science 106 (1993) 891-901
5. Bermudez E., Mangum J.B., Wong B.A., Asgharian B., Hext P.M., Warheit D.B., and Everitt J.I. Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles. Toxicological Sciences 77 (2004) 347-357
6. Binet F., Cavalli H., Moisan E., and Girard D. Arsenic trioxide (AT) is a novel human neutrophil pro-apoptotic agent: effects of catalase on AT-induced apoptosis, degradation of cytoskeletal proteins and de novo protein synthesis. British Journal of Haematology 132 (2006) 349-358
7. Binet F., Chiasson S., and Girard D. Arsenic trioxide induces de novo protein synthesis of annexin-1 in neutrophils: association with a heat shock-like response and not apoptosis. British Journal of Haematology 140 (2008) 454-463
8. Binet F., and Girard D. Novel human neutrophil agonistic properties of arsenic trioxide: involvement of p38 mitogen-activated protein kinase and/or c-jun NH2-terminal MAPK but not extracellular signal-regulated kinases-1/2. Journal of Leukocyte Biology 84 (2008) 1613-1622
9. Blackford Jr. J.A., Jones W., Dey R.D., and Castranova V. Comparison of inducible nitric oxide synthase gene expression and lung inflammation following intratracheal instillation of silica, coal, carbonyl iron, or titanium dioxide in rats. Journal of Toxicology and Environmental Health 51 (1997) 203-218
10. Brien W.W., Salvati E.A., Betts F., Bullough P., Wright T., Rimnac C., Buly R., and Garvin K. Metal levels in cemented total hip arthroplasty. A comparison of well-fixed and loose implants. Clinical Orthopaedics and Related Research (1992) 66-74
11. Buly R.L., Huo M.H., Salvati E., Brien W., and Bansal M. Titanium wear debris in failed cemented total hip arthroplasty. An analysis of 71 cases. Journal of Arthroplasty 7 (1992) 315-323
12. Chen J., Dong X., Zhao J., and Tang G. In vivo acute toxicity of titanium dioxide nanoparticles to mice after intraperitoneal injection. Journal of Applied Toxicology 29 (2009) 330-337
13. Girard D., Paquet M.E., Paquin R., and Beaulieu A.D. Differential effects of interleukin-15 (IL-15) and IL-2 on human neutrophils: modulation of phagocytosis, cytoskeleton rearrangement, gene expression, and apoptosis by IL-15. Blood 88 (1996) 3176-3184
14. Girard D., Paquin R., Naccache P.H., and Beaulieu A.D. Effects of interleukin-13 on human neutrophil functions. Journal of Leukocyte Biology 59 (1996) 412-419
15. Girard D., Paquin R., and Beaulieu A.D. Responsiveness of human neutrophils to interleukin-4: induction of cytoskeletal rearrangements, de novo protein synthesis and delay of apoptosis. Biochemical Journal 325 Pt 1 (1997) 147-153
16. Harter L., Keel M., Steckholzer U., Ungethuem U., Trentz O., and Ertel W. Activation of mitogen-activated protein kinases during granulocyte apoptosis in patients with severe sepsis. Shock 18 (2002) 401-406
17. Hedenborg M. Titanium dioxide induced chemiluminescence of human polymorphonuclear leukocytes. International Archives of Occupational and Environmental Health 61 (1988) 1-6
18. Jin C.Y., Zhu B.S., Wang X.F., and Lu Q.H. Cytotoxicity of titanium dioxide nanoparticles in mouse fibroblast cells. Chemical Research in Toxicology 21 (2008) 1871-1877
19. Kang S.J., Kim B.M., Lee Y.J., Hong S.H., and Chung H.W. Titanium dioxide nanoparticles induce apoptosis through the JNK/p38-caspase-8-Bid pathway in phytohemagglutinin-stimulated human lymphocytes. Biochemical and Biophysical Research Communications 386 (2009) 682-687
20. Kennedy A.D., and DeLeo F.R. Neutrophil apoptosis and the resolution of infection. Immunologic Research 43 (2009) 25-61
21. Klein J.B., Rane M.J., Scherzer J.A., Coxon P.Y., Kettritz R., Mathiesen J.M., Buridi A., and McLeish K.R. Granulocyte-macrophage colony-stimulating factor delays neutrophil constitutive apoptosis through phosphoinositide 3-kinase and extracellular signal-regulated kinase pathways. Journal of Immunology 164 (2000) 4286-42891
22. Krump E., Sanghera J.S., Pelech S.L., Furuya W., and Grinstein S. Chemotactic peptide N-formyl-met-leu-phe activation of p38 mitogen-activated protein kinase (MAPK) and MAPK-activated protein kinase-2 in human neutrophils. Journal of Biological Chemistry 272 (1997) 937-944
23. Laroui, H., Dalmasso, G., Nguyen, H.T., Yan, Y., Sitaraman, S.V., Merlin, D., 2009. Drug-loaded nanoparticles targeted to the colon with polysaccharide hydrogel reduce colitis in a mouse model. Gastroenterology, Nov. 9 [Epub ahead of print].
24. Long T.C., Tajuba J., Sama P., Saleh N., Swartz C., Parker J., Hester S., Lowry G.V., and Veronesi B. Nanosize titanium dioxide stimulates reactive oxygen species in brain microglia and damages neurons in vitro. Environmental Health Perspectives 115 (2007) 1631-1637
25. Maurer M., and von Stebut E. Macrophage inflammatory protein-1. International Journal of Biochemistry and Cell Biology 36 (2004) 1882-1886
26. Mocsai A., Jakus Z., Vantus T., Berton G., Lowell C.A., and Ligeti E. Kinase pathways in chemoattractant-induced degranulation of neutrophils: the role of p38 mitogen-activated protein kinase activated by Src family kinases. Journal of Immunology 164 (2000) 4321-4331
27. Moghimi S.M., Hunter A.C., and Murray J.C. Nanomedicine: current status and future prospects. FASEB Journal 19 (2005) 311-330
28. Moisan E., Arbour S., Nguyen N., Hebert M.J., Girard D., Bernier J., Fournier M., and Kouassi E. Prolongation of human neutrophil survival by low-level mercury via inhibition of spontaneous apoptosis. Journal of Toxicology and Environmental Health A65 (2002) 183-203
29. Nemmar A., Melghit K., and Ali B.H. The acute proinflammatory and prothrombotic effects of pulmonary exposure to rutile TiO2 nanorods in rats. Experimental Biology and Medicine 233 (2008) 610-619
30. Osano E., Kishi J., and Takahashi Y. Phagocytosis of titanium particles and necrosis in TNF-alpha-resistant mouse sarcoma L929 cells. Toxicology in Vitro 17 (2003) 41-47
31. Park E.J., Yi J., Chung K.H., Ryu D.Y., Choi J., and Park K. Oxidative stress and apoptosis induced by titanium dioxide nanoparticles in cultured BEAS-2B cells. Toxicology Letters 180 (2008) 222-229
32. Park E.J., Yoon J., Choi K., Yi J., and Park K. Induction of chronic inflammation in mice treated with titanium dioxide nanoparticles by intratracheal instillation. Toxicology 260 (2009) 37-46
33. Pelletier M., Bouchard A., and Girard D. In vivo and in vitro roles of IL-21 in inflammation. Journal of Immunology 173 (2004) 7521-7530
34. Pelletier M., Ratthe C., and Girard D. Mechanisms involved in interleukin-15-induced suppression of human neutrophil apoptosis: role of the anti-apoptotic Mcl-1 protein and several kinases including Janus kinase-2, p38 mitogen-activated protein kinase and extracellular signal-regulated kinases-1/2. FEBS Letters 532 (2002) 164-170
35. 3 is a neutrophil but not a HL-60 cell agonist. Clinical Immunology 96 (2000) 131-139
36. Pioletti D.P., Takei H., Kwon S.Y., Wood D., and Sung K.L. The cytotoxic effect of titanium particles phagocytosed by osteoblasts. Journal of Biomedical Materials Research 46 (1999) 399-407
37. Pliyev B.K. Chemotactically active proteins of neutrophils. Biochemistry 73 (2008) 970-984
38. Puccetti G., and Leblanc R.M. A sunscreen-tanning compromise: 3D visualization of the actions of titanium dioxide particles and dihydroxyacetone on human epiderm. Photochemistry and Photobiology 71 (2000) 426-430
39. Radnai M., Csonka C., Dux L., and Fazekas A. Adsorption of human serum proteins to titanium dioxide. Fogorvosi Szemle 93 (2000) 329-334
40. Schanen B.C., Karakoti A.S., Seal S., Drake III D.R., Warren W.L., and Self W.T. Exposure to titanium dioxide nanomaterials provokes inflammation of an in vitro human immune construct. ACS Nano 3 (2009) 2523-2532
41. Serhan C.N., and Savill J. Resolution of inflammation: the beginning programs the end. Nature Immunology 6 (2005) 1191-1197
42. Smith J.A. Neutrophils, host defense, and inflammation: a double-edged sword. Journal of Leukocyte Biology 56 (1994) 672-686
43. 2 nanoparticles: studies on a human monoblastoid cell line. Toxicology in Vitro 22 (2008) 1689-1696
44. Ward C., Murray J., Clugston A., Dransfield I., Haslett C., and Rossi A.G. Interleukin-10 inhibits lipopolysaccharide-induced survival and extracellular signal-regulated kinase activation in human neutrophils. European Journal of Immunology 35 (2005) 2728-2737
45. Whyte M.K., Savill J., Meagher L.C., Lee A., and Haslett C. Coupling of neutrophil apoptosis to recognition by macrophages: coordinated acceleration by protein synthesis inhibitors. Journal of Leukocyte Biology 62 (1997) 195-202