Focus on Molecules: Lecithin retinol acyltransferase

Experimental Eye Research

Volumn 90, Issue 2, 2010, Pages 186-187

  Ruiz, Alberto ^a,b   Bok, Dean ^a,b  

^a JULES STEIN EYE INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

LRAT; Retinal pigment epithelium; Retinyl esters; Visual cycle

Indexed keywords

LECITHIN RETINOL ACYLTRANSFERASE; MEMBRANE ENZYME; PAPAIN; PROTEIN P60; PROTEIN RPE65; PROTEIN STRA6; RETINOL DEHYDROGENASE; RETINOL DEHYDROGENASE 11; RETINOL DEHYDROGENASE 5; RETINOL ESTER; THIOL PROTEINASE; UNCLASSIFIED DRUG; VISUAL PROTEINS AND PIGMENTS;

AMINO TERMINAL SEQUENCE; CARBOXY TERMINAL SEQUENCE; CARCINOGENESIS; CATALYSIS; CENTRAL SCOTOMA; CHROMOSOME 4Q; DISEASE SEVERITY; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME MECHANISM; ENZYME STRUCTURE; GENE MUTATION; GENETIC CONSERVATION; GENETIC POLYMORPHISM; HUMAN; MOLECULAR CLONING; MOLECULAR INTERACTION; NONHUMAN; NYSTAGMUS; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; RETINA DEGENERATION; RETINA DYSTROPHY; RETINITIS PIGMENTOSA; SEQUENCE ALIGNMENT; SHORT SURVEY; SITE DIRECTED MUTAGENESIS; VISUAL IMPAIRMENT;

ACYLTRANSFERASES; ESTERIFICATION; HUMANS; RETINAL DISEASES; RETINAL PIGMENT EPITHELIUM; VISUAL PATHWAYS;

EID: 77649191576     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2009.07.002     Document Type: Short Survey

References (4)

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3. Ruiz A., Bok D. Molecular characterization of lecithin retinol acyltransferase. Methods in Enzymology 2000, vol. 316:400-413. Academic Press, New York. K. Palcsewski (Ed.).
4. Travis G.H., Golczak M., Moise A.R., Palcsewski K. Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents. Ann. Rev. Pharmacol. Toxicol. 2007, 47:469-512.