Partitioning and phase equilibria of PEGylated excipients in fluorinated liquids

International Journal of Pharmaceutics

Volumn 387, Issue 1-2, 2010, Pages 230-235

  Paul, Alison ^a   Talbot, Gemma L ^a   Bowles, James W ^a   James, Jennifer ^a   Griffiths, Peter C ^a   Rogueda, Philippe G ^b  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b NOVARTIS HORSHAM RESEARCH CENTRE   (United Kingdom)

Author keywords

End group contribution; Ethylene glycol; Ethylene oxide oligomers; Fluorinated solvents; Lower consolute solution temperature; Partitioning NMR; Phase equilibria; Solubility

Indexed keywords

2H,3H PERFLUOROPENTANE; MACROGOL; MACROGOL 200; MACROGOL 400; PERFLUOROPENTANE; POLYMER; SOLVENT; UNCLASSIFIED DRUG;

ARTICLE; HYDROGEN BOND; METHYLATION; MOLECULAR WEIGHT; NUCLEAR MAGNETIC RESONANCE; PHASE PARTITIONING; PHASE SEPARATION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SOLUBILITY;

CHLOROFLUOROCARBONS, METHANE; EXCIPIENTS; FLUOROCARBONS; METHYLATION; MOLECULAR WEIGHT; PHASE TRANSITION; POLYETHYLENE GLYCOLS; SOLUBILITY; SOLVENTS;

EID: 77649189368     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2009.12.004     Document Type: Article

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