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Volumn 129, Issue 1, 2010, Pages 53-55

The sound of silence: Human β-defensin-1 gene untranslated SNPs change the predicted mRNA secondary structure in a length-dependent manner

Author keywords

Alternative transcription initiation; DEFB1; Regulation of gene expression; RNA secondary structure

Indexed keywords

BETA DEFENSIN 1; MESSENGER RNA;

EID: 77649189040     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imlet.2009.12.024     Document Type: Letter
Times cited : (15)

References (23)
  • 1
    • 0141799911 scopus 로고    scopus 로고
    • Defensins: antimicrobial peptides of innate immunity
    • Ganz T. Defensins: antimicrobial peptides of innate immunity. Nature Reviews 3 (2003) 710-720
    • (2003) Nature Reviews , vol.3 , pp. 710-720
    • Ganz, T.1
  • 2
    • 49849095345 scopus 로고    scopus 로고
    • Single-nucleotide polymorphisms in human beta-defensin-1 gene in Mozambican HIV-1-infected women and correlation with virologic parameters
    • Baroncelli S., Ricci E., Andreotti M., Guidotti G., Germano P., Marazzi M.C., et al. Single-nucleotide polymorphisms in human beta-defensin-1 gene in Mozambican HIV-1-infected women and correlation with virologic parameters. AIDS (London, England) 22 (2008) 1515-1517
    • (2008) AIDS (London, England) , vol.22 , pp. 1515-1517
    • Baroncelli, S.1    Ricci, E.2    Andreotti, M.3    Guidotti, G.4    Germano, P.5    Marazzi, M.C.6
  • 4
    • 34848838572 scopus 로고    scopus 로고
    • Functional analysis of the host defense peptide human beta defensin-1: new insight into its potential role in cancer
    • Bullard R.S., Gibson W., Bose S.K., Belgrave J.K., Eaddy A.C., Wright C.J., et al. Functional analysis of the host defense peptide human beta defensin-1: new insight into its potential role in cancer. Molecular Immunology 45 (2008) 839-848
    • (2008) Molecular Immunology , vol.45 , pp. 839-848
    • Bullard, R.S.1    Gibson, W.2    Bose, S.K.3    Belgrave, J.K.4    Eaddy, A.C.5    Wright, C.J.6
  • 5
    • 70449598242 scopus 로고    scopus 로고
    • Predicting alternative candidates as binding sites to DEFB1 668 (-44) SNP: a long way from statistical association with multifactorial diseases
    • Naslavsky M.S., Rocha C.R.C., Lima Filho J.L., and Crovella S. Predicting alternative candidates as binding sites to DEFB1 668 (-44) SNP: a long way from statistical association with multifactorial diseases. Infection, Genetics and Evolution (2009)
    • (2009) Infection, Genetics and Evolution
    • Naslavsky, M.S.1    Rocha, C.R.C.2    Lima Filho, J.L.3    Crovella, S.4
  • 6
    • 33845968880 scopus 로고    scopus 로고
    • Human beta-defensins kill Candida albicans in an energy-dependent and salt-sensitive manner without causing membrane disruption
    • Vylkova S., Nayyar N., Li W., and Edgerton M. Human beta-defensins kill Candida albicans in an energy-dependent and salt-sensitive manner without causing membrane disruption. Antimicrobial Agents and Chemotherapy 51 (2007) 154-161
    • (2007) Antimicrobial Agents and Chemotherapy , vol.51 , pp. 154-161
    • Vylkova, S.1    Nayyar, N.2    Li, W.3    Edgerton, M.4
  • 8
    • 2542480000 scopus 로고    scopus 로고
    • Multiple roles of antimicrobial defensins, cathelicidins, and eosinophil-derived neurotoxin in host defense
    • Yang D., Biragyn A., Hoover D.M., Lubkowski J., and Oppenheim J.J. Multiple roles of antimicrobial defensins, cathelicidins, and eosinophil-derived neurotoxin in host defense. Annual Review of Immunology 22 (2004) 181-215
    • (2004) Annual Review of Immunology , vol.22 , pp. 181-215
    • Yang, D.1    Biragyn, A.2    Hoover, D.M.3    Lubkowski, J.4    Oppenheim, J.J.5
  • 9
    • 68649115023 scopus 로고    scopus 로고
    • SNP 668C (-44) alters a NF-kappaB1 putative binding site in non-coding strand of human beta-defensin 1 (DEFB1) and is associated with lepromatous leprosy
    • Prado-Montes de Oca E., Velarde-Felix J.S., Rios-Tostado J.J., Picos-Cardenas V.J., and Figuera L.E. SNP 668C (-44) alters a NF-kappaB1 putative binding site in non-coding strand of human beta-defensin 1 (DEFB1) and is associated with lepromatous leprosy. Infection, Genetics and Evolution 9 (2009) 617-625
    • (2009) Infection, Genetics and Evolution , vol.9 , pp. 617-625
    • Prado-Montes de Oca, E.1    Velarde-Felix, J.S.2    Rios-Tostado, J.J.3    Picos-Cardenas, V.J.4    Figuera, L.E.5
  • 10
    • 33749036894 scopus 로고    scopus 로고
    • Human beta-defensin-1, a potential chromosome 8p tumor suppressor: control of transcription and induction of apoptosis in renal cell carcinoma
    • Sun C.Q., Arnold R., Fernandez-Golarz C., Parrish A.B., Almekinder T., He J., et al. Human beta-defensin-1, a potential chromosome 8p tumor suppressor: control of transcription and induction of apoptosis in renal cell carcinoma. Cancer Research 66 (2006) 8542-8549
    • (2006) Cancer Research , vol.66 , pp. 8542-8549
    • Sun, C.Q.1    Arnold, R.2    Fernandez-Golarz, C.3    Parrish, A.B.4    Almekinder, T.5    He, J.6
  • 11
    • 34250869638 scopus 로고    scopus 로고
    • Transcriptional effect of DEFB1 gene 5′ untranslated region polymorphisms
    • [author reply 5997]
    • Milanese M., Segat L., and Crovella S. Transcriptional effect of DEFB1 gene 5′ untranslated region polymorphisms. Cancer Research 67 (2007) 5997 [author reply 5997]
    • (2007) Cancer Research , vol.67 , pp. 5997
    • Milanese, M.1    Segat, L.2    Crovella, S.3
  • 12
    • 70350504612 scopus 로고    scopus 로고
    • Association of a genetic polymorphism (-44C/G SNP) in the human DEFB1 gene with expression and inducibility of multiple beta-defensins in gingival keratinocytes
    • Kalus A.A., Fredericks L.P., Hacker B.M., Dommisch H., Presland R.B., Kimball J.R., et al. Association of a genetic polymorphism (-44C/G SNP) in the human DEFB1 gene with expression and inducibility of multiple beta-defensins in gingival keratinocytes. BMC Oral Health 9 (2009) 21
    • (2009) BMC Oral Health , vol.9 , pp. 21
    • Kalus, A.A.1    Fredericks, L.P.2    Hacker, B.M.3    Dommisch, H.4    Presland, R.B.5    Kimball, J.R.6
  • 13
    • 54149112918 scopus 로고    scopus 로고
    • The signature of long-standing balancing selection at the human defensin beta-1 promoter
    • Cagliani R., Fumagalli M., Riva S., Pozzoli U., Comi G.P., Menozzi G., et al. The signature of long-standing balancing selection at the human defensin beta-1 promoter. Genome Biology 9 (2008) R143
    • (2008) Genome Biology , vol.9
    • Cagliani, R.1    Fumagalli, M.2    Riva, S.3    Pozzoli, U.4    Comi, G.P.5    Menozzi, G.6
  • 17
    • 12344281782 scopus 로고    scopus 로고
    • The implications of structured 5′ untranslated regions on translation and disease
    • Pickering B.M., and Willis A.E. The implications of structured 5′ untranslated regions on translation and disease. Seminars in Cell & Developmental Biology 16 (2005) 39-47
    • (2005) Seminars in Cell & Developmental Biology , vol.16 , pp. 39-47
    • Pickering, B.M.1    Willis, A.E.2
  • 18
    • 34547429389 scopus 로고    scopus 로고
    • Genomic variations within DEFB1 are associated with the susceptibility to and the fatal outcome of severe sepsis in Chinese Han population
    • Chen Q.X., Lv C., Huang L.X., Cheng B.L., Xie G.H., Wu S.J., et al. Genomic variations within DEFB1 are associated with the susceptibility to and the fatal outcome of severe sepsis in Chinese Han population. Genes and Immunity 8 (2007) 439-443
    • (2007) Genes and Immunity , vol.8 , pp. 439-443
    • Chen, Q.X.1    Lv, C.2    Huang, L.X.3    Cheng, B.L.4    Xie, G.H.5    Wu, S.J.6
  • 20
    • 38549086390 scopus 로고    scopus 로고
    • Association of beta-defensin-1 gene polymorphisms with Pseudomonas aeruginosa airway colonization in cystic fibrosis
    • Tesse R., Cardinale F., Santostasi T., Polizzi A., Manca A., Mappa L., et al. Association of beta-defensin-1 gene polymorphisms with Pseudomonas aeruginosa airway colonization in cystic fibrosis. Genes and Immunity 9 (2008) 57-60
    • (2008) Genes and Immunity , vol.9 , pp. 57-60
    • Tesse, R.1    Cardinale, F.2    Santostasi, T.3    Polizzi, A.4    Manca, A.5    Mappa, L.6
  • 22
    • 33645162401 scopus 로고    scopus 로고
    • Asthma and atopy are associated with DEFB1 polymorphisms in Chinese children
    • Leung T.F., Li C.Y., Liu E.K., Tang N.L., Chan I.H., Yung E., et al. Asthma and atopy are associated with DEFB1 polymorphisms in Chinese children. Genes and Immunity 7 (2006) 59-64
    • (2006) Genes and Immunity , vol.7 , pp. 59-64
    • Leung, T.F.1    Li, C.Y.2    Liu, E.K.3    Tang, N.L.4    Chan, I.H.5    Yung, E.6
  • 23
    • 0034670356 scopus 로고    scopus 로고
    • Do the 5′ untranslated domains of human cDNAs challenge the rules for initiation of translation (or is it vice versa)?
    • Kozak M. Do the 5′ untranslated domains of human cDNAs challenge the rules for initiation of translation (or is it vice versa)?. Genomics 70 (2000) 396-406
    • (2000) Genomics , vol.70 , pp. 396-406
    • Kozak, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.