Preclinical studie of general toxic properties of preparations containing ultralow doses of antibodies to endogenous regulators

Bulletin of Experimental Biology and Medicine

Volumn 148, Issue 3, 2009, Pages 543-546

  Karpova, G V ^a   Fomina, T I ^a   Vetoshkina, T V ^a   Dubskaya, T Yu ^a   Voronova, O L ^a   Timina, E A ^a   Abramova, E V ^a   Ermolaeva, L A ^a   Perova, A V ^a  

^a INSTITUTE OF PHARMACOLOGY   (Russian Federation)

Author keywords

Acute toxicity; Chronic toxicity; Local irritating effect; Preclinical study; Ultralow doses of antibodies

Indexed keywords

AFALA; ANAFERON; ARTROFOON; IMPAZA; POETAM; PROPROTEN 100; PROTEIN ANTIBODY; UNCLASSIFIED DRUG; ANTIBODY; MONOCLONAL ANTIBODY;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ARTICLE; CHRONIC DRUG ADMINISTRATION; CHRONIC TOXICITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG SAFETY; DRUG SCREENING; DRUG TOLERANCE; FEMALE; HISTOLOGY; LD 50; MALE; MOUSE; NEUTROPHIL COUNT; NONHUMAN; RABBIT; RAT; SINGLE DRUG DOSE; STOMACH IRRITATION; TOXICITY TESTING; TOXICOLOGY; WEIGHT GAIN; ANIMAL;

ANIMALIA;

ANIMALS; ANTIBODIES; ANTIBODIES, MONOCLONAL; DOSE-RESPONSE RELATIONSHIP, DRUG; MICE; RABBITS; RATS; TOXICITY TESTS;

EID: 77649188648     PISSN: 00074888     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10517-010-0760-3     Document Type: Article

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