Synthesis of nontrivial quinopimaric acid derivatives by oxidation with dimethyldioxirane

Tetrahedron Letters

Volumn 51, Issue 14, 2010, Pages 1832-1835

  Kazakova, Oxana B ^a   Tretyakova, Elena V ^a   Kukovinets, Olga S ^a   Abdrakhmanova, Albina R ^a   Kabalnova, Nataliya N ^a   Kazakov, Dmitri V ^a   Tolstikov, Genrikh A ^a   Gubaidullin, Aidar T ^b  

^a INSTITUTE OF ORGANIC CHEMISTRY   (Russian Federation)

^b A E ARBUZOV INSTITUTE OF ORGANIC AND PHYSICAL CHEMISTRY   (Russian Federation)

Author keywords

Dimethyldioxirane; Diterpenoids; Natural products; Oxidation; Quinopimaric acid

Indexed keywords

4BETA HYDROXY 4ALPHA,14ALPAH EPOXY 13(15) ENE DIHYDROQUINOPIMARIC ACID METHYL ESTER; ACETAL; ANTIVIRUS AGENT; DIMETHYLDIOXIRANE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL BOND; CRYSTAL STRUCTURE; CYCLIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H3N2; NONHUMAN; OXIDATION; PAPILLOMA VIRUS; RING OPENING; STEREOCHEMISTRY;

INFLUENZA A VIRUS; PAPILLOMAVIRIDAE;

EID: 77649187824     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2010.01.117     Document Type: Article

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21. -3). Crystallographic data (excluding structure factors) have been deposited at the Cambridge Crystallographic Data Centre (CCDC) as Supplementary Publication No. CCDC 704775 (http://www.ccdc.cam.ac.uk/products/csd/request/). Refinement using shelxtl.
22. -3). Crystallographic data (excluding structure factors) have been deposited at the Cambridge Crystallographic Data Centre as Supplementary Publication No. CCDC 717983 (http://www.ccdc.cam.ac.uk/products/csd/request/). Refinement using shelxtl.
23. 5 (%): S{cyrillic}, 72.94; N{cyrillic}, 9.07. Found (%): S{cyrillic}, 72.85; N{cyrillic}, 9.10.
24. The protocols and explanations of the test results are available at the AACF website (www.niaid-aacf.org).