Effects of selective Cox-2 inhibitor, rofecoxib, alone or combination with furosemide on renal functions and renal Cox-2 expression in rats

Clinical and Experimental Nephrology

Volumn 14, Issue 1, 2010, Pages 22-27

  Kose, Fatih ^a   Besen, Ayberk ^a   Paydas, Saime ^a   Balal, Mustafa ^a   Gonlusen, Gulfiliz ^a   Inal, Tamer ^a   Dogan, Ayse ^a   Kibar, Mustafa ^a  

^a CUKUROVA UNIVERSITY   (Turkey)

Author keywords

Cox 2 expression; Diuretic effect; Selective Cox 2 inhibitor induced nephrotoxicity

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CREATININE; CYCLOOXYGENASE 2; FUROSEMIDE; PLACEBO; POTASSIUM; RENIN; ROFECOXIB; SODIUM;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY WEIGHT; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; CREATININE URINE LEVEL; DIURESIS; DRUG EFFECT; ENZYME INHIBITION; IMMUNOHISTOCHEMISTRY; KIDNEY FAILURE; KIDNEY FUNCTION; MALE; NONHUMAN; PLASMA RENIN ACTIVITY; POTASSIUM BLOOD LEVEL; POTASSIUM URINE LEVEL; PROTEIN EXPRESSION; RAT; SODIUM BLOOD LEVEL; SODIUM URINE LEVEL; STATISTICAL ANALYSIS; UREA NITROGEN BLOOD LEVEL; URINE OSMOLALITY; URINE VOLUME;

ANIMALS; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; FUROSEMIDE; GENE EXPRESSION; KIDNEY; LACTONES; MALE; OSMOLAR CONCENTRATION; POTASSIUM; RATS; RATS, WISTAR; RENIN; SULFONES; URINE;

EID: 77649186644     PISSN: 13421751     EISSN: 14377799     Source Type: Journal    
DOI: 10.1007/s10157-009-0214-2     Document Type: Article

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