Effects of V279F in the Lp-PLA2 gene on markers of oxidative stress and inflammation in Koreans

Clinica Chimica Acta

Volumn 411, Issue 7-8, 2010, Pages 486-493

  Paik, Jean Kyung ^a,b   Chae, Jey Sook ^a   Jang, Yangsoo ^a,c   Kim, Ji Young ^a   Kim, Oh Yoen ^a   Jeong, Tae Sook ^d   Lee, Sang Hyun ^e   Lee, Jong Ho ^a  

^a Yonsei University   (South Korea)

^b Seoul Fellowship   (South Korea)

^c Yonsei University College of Medicine   (South Korea)

^d Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^e National Health Insurance Corporation   (South Korea)

Author keywords

Inflammation; LDL cholesterol; Lp PLA2; Oxidative stress; V279F

Indexed keywords

1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; 8 ISOPROSTAGLANDIN F2 ALPHA; APOLIPOPROTEIN B; ARACHIDONIC ACID; C REACTIVE PROTEIN; FATTY ACID; FIBRINOGEN; LIPID PEROXIDE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; OXIDIZED LOW DENSITY LIPOPROTEIN; PHOSPHOLIPID;

ADULT; AGED; ALLELE; ANTHROPOMETRIC PARAMETERS; ARTICLE; CONTROLLED STUDY; DISEASE MARKER; ENZYME ACTIVITY; FEMALE; GENOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; HUMAN EXPERIMENT; INFLAMMATION; KOREA; LIPID ANALYSIS; LIPID COMPOSITION; LIPID PEROXIDATION; MALE; NORMAL HUMAN; OXIDATIVE STRESS; PHOSPHOLIPID BLOOD LEVEL; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

1-ALKYL-2-ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; ADULT; AGED; BIOLOGICAL MARKERS; FEMALE; GENOTYPE; HUMANS; INFLAMMATION; KOREA; MALE; MIDDLE AGED; OXIDATIVE STRESS; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 77649184125     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2009.12.021     Document Type: Article

References (44)

1. 2 gene is associated with catalytic activities and cardiovascular disease in Korean men. J Clin Endocrinol Metab 2006, 91:3521-3527.
2. 2 protein expression in the natural progression of human coronary atherosclerosis. Arterioscler Thromb Vasc Biol 2006, 26:2523-2529.
3. 2 and prognosis after myocardial infarction in the community. Arterioscler Thromb Vasc Biol 2006, 26:2517-2522.
4. Yamada Y., Yoshida H., Ichihara S., Imaizumi T., Satoh K., Yokota M. Correlations between plasma platelet-activating factor acetylhydrolase (PAF-AH) activity and PAF-AH genotype, age, and atherosclerosis in a Japanese population. Atherosclerosis 2000, 150:209-216.
5. Yamada Y., Ichihara S., Fujimura T., Yokota M. Identification of the G994->T missense in exon 9 of the plasma platelet-activating factor acetylhydrolase gene as an independent risk factor for coronary artery disease in Japanese men. Metabolism 1998, 47:177-181.
6. Hiramoto M., Yoshida H., Imaizumi T., Yoshimizu N., Satoh K. A mutation in plasma platelet-activating factor acetylhydrolase (Val279->Phe) is a genetic risk factor for stroke. Stroke 1997, 28:2417-2420.
7. Itabe H. Oxidized phospholipids as a new landmark in atherosclerosis. Prog Lipid Res 1998, 37:181-207.
8. 2 activity is associated with coronary artery disease and markers of oxidative stress: a case-control study. Am J Clin Nutr 2008, 88:630-637.
9. 2 as an independent predictor of coronary heart disease. West of Scotland Coronary Prevention Study Group. N Engl J Med 2000, 343:1148-1155.
10. 2 adds to risk prediction of incident coronary events by C-reactive protein in apparently healthy middle-aged men from the general population: results from the 14-year follow-up of a large cohort from southern Germany. Circulation 2004, 110:1903-1908.
11. Six D.A., Dennis E.A. The expanding superfamily of phospholipase A(2) enzymes: classification and characterization. Biochim Biophys Acta 2000, 1488:1-19.
12. 2 in atherosclerosis: biology, epidemiology, and possible therapeutic target. Arterioscler Thromb Vasc Biol 2005, 25:923-931.
13. Stafforini D.M., Sheller J.R., Blackwell T.S., et al. Release of free F2-isoprostanes from esterified phospholipids is catalyzed by intracellular and plasma platelet-activating factor acetylhydrolases. J Biol Chem 2006, 281:4616-4623.
14. Mehrabi M.R., Serbecic N., Ekmekcioglu C., et al. The isoprostane 8-epi-PGF(2alpha) is a valuable indicator of oxidative injury in human heart valves. Cardiovasc Pathol 2001, 10:241-245.
15. Miwa M., Miyake T., Yamanaka T., et al. Characterization of serum platelet-activating factor (PAF) acetylhydrolase. Correlation between deficiency of serum PAF acetylhydrolase and respiratory symptoms in asthmatic children. J Clin Invest 1988, 82:1983-1991.
16. Naoki K., Asano K., Satoh N., et al. PAF responsiveness in Japanese subjects with plasma PAF acetylhydrolase deficiency. Biochem Biophys Res Commun 2004, 317:205-210.
17. Lee E.S., Jiang J., Sund G.C., et al. Recombinant human platelet-activating factor acetylhydrolase reduces the frequency of diabetes in the diabetes-prone BB rat. Diabetes 1999, 48:43-49.
18. Quarck R., De Geest B., Stengel D., et al. Adenovirus-mediated gene transfer of human platelet-activating factor-acetylhydrolase prevents injury-induced neointima formation and reduces spontaneous atherosclerosis in apolipoprotein E-deficient mice. Circulation 2001, 103:2495-2500.
19. 2). Cardiovasc Drugs Ther 2009, 23:73-83.
20. Friedewald W.T., Levy R.I., Fredrickson D.S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972, 18:499-502.
21. Folch J., Lees M., Sloane Stanley G.H. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 1957, 226:497-509.
22. Lepage G., Roy C.C. Direct transesterification of all classes of lipids in a one-step reaction. J Lipid Res 1986, 27:114-120.
23. Morrow J.D. Quantification of isoprostanes as indices of oxidant stress and the risk of atherosclerosis in humans. Arterioscler Thromb Vasc Biol 2005, 25:279-286.
24. 2 gene on the plasma oxidized LDL level and carotid intima-media thickness in Japanese: the Shimane study. Am J Hypertens 2009, 22:742-747.
25. 2) deficiency patients. J Hum Genet 2004, 49:302-307.
26. Kim P.S., Arvan P. Endocrinopathies in the family of endoplasmic reticulum (ER) storage diseases: disorders of protein trafficking and the role of ER molecular chaperones. Endocr Rev 1998, 19:173-202.
27. Zhang K., Kaufman R.J. Signaling the unfolded protein response from the endoplasmic reticulum. J Biol Chem 2004, 279:25935-25938.
28. Schwedhelm E., Bartling A., Lenzen H., et al. Urinary 8-iso-prostaglandin F2alpha as a risk marker in patients with coronary heart disease: a matched case-control study. Circulation 2004, 109:843-848.
29. Moore K.P., Darley-Usmar V., Morrow J., Roberts L.J. Formation of F2-isoprostanes during oxidation of human low-density lipoprotein and plasma by peroxynitrite. Circ Res 1995, 77:335-341.
30. Reilly M.P., Praticò D., Delanty N., et al. Increased formation of distinct F2 isoprostanes in hypercholesterolemia. Circulation 1998, 98:2822-2828.
31. Praticò D., Iuliano L., Mauriello A., et al. Localization of distinct F2-isoprostanes in human atherosclerotic lesions. J Clin Invest 1997, 100:2028-2034.
32. Miyaura S., Eguchi H., Johnston J.M. Effect of a cigarette smoke extract on the metabolism of the proinflammatory autacoid, platelet-activating factor. Circ Res 1992, 70:341-347.
33. 2 biochemistry. Cardiovasc Drugs Ther 2009, 23:49-59.
34. Kono N., Inoue T., Yoshida Y., et al. Protection against oxidative stress-induced hepatic injury by intracellular type II platelet-activating factor acetylhydrolase by metabolism of oxidized phospholipids in vivo. J Biol Chem 2008, 283:1628-1636.
35. National Health and Nutrition Survey 2005, Korean Ministry for Health, Welfare and Family Affairs.
36. Kuivenhoven J.A., de Knijff P., Boer J.M., et al. Heterogeneity at the CETP gene locus Influence on plasma CETP concentrations and HDL cholesterol levels. Arterioscler Thromb Vasc Biol 1997, 17:560-568.
37. Deeb S.S., Zambon A., Carr M.C., Ayyobi A.F., Brunzell J.D. Hepatic lipase and dyslipidemia: interactions between genetic variants, obesity, gender and diet. J Lipid Res 2003, 16:16.
38. Falchi A., Piras I.S., Vona G., et al. Cholesteryl ester transfer protein gene polymorphisms are associated with coronary artery disease in Corsican population (France). Exp Mol Pathol 2007, 83:25-29.
39. Freeman D.J., Griffin B.A., Holmes A.P., et al. Regulation of plasma HDL cholesterol and subfraction distribution by genetic and environmental factors: associations between the TaqI B RFLP in the CETP gene and smoking and obesity. Arterioscler Thromb 1994, 14:336-344.
40. Ordovas J.M., Cupples L.A., Corella D., et al. Association of cholesteryl ester transfer protein-TaqIB polymorphism with variations in lipoprotein subclasses and coronary heart disease risk: the Framingham study. Arterioscler Thromb Vasc Biol 2000, 20:1323-1329.
41. Corbex M., Poirier O., Fumeron F., et al. Extensive association analysis between the CETP gene and coronary heart disease phenotypes reveals several putative functional polymorphisms and gene-environment interaction. Genet Epidemiol 2000, 19:64-80.
42. Hannuksela M., Marcel Y.L., Kesaniemi Y.A., Savolainen M.J. Reduction in the concentration and activity of plasma cholesteryl ester transfer protein by alcohol. J Lipid Res 1992, 33:737-744.
43. Fumeron F., Betoulle D., Luc G., et al. Alcohol intake modulates the effect of a polymorphism of the cholesteryl ester transfer protein gene on plasma high density lipoprotein and the risk of myocardial infarction. J Clin Invest 1995, 96:1664-1671.
44. Vohl M.C., Lamarche B., Pascot A., et al. Contribution of the cholesteryl ester transfer protein gene TaqIB polymorphism to the reduced plasma HDL-cholesterol levels found in abdominal obese men with the features of the insulin resistance syndrome. Int J Obes 1999, 23:918-925.