Response to intravenous antidepressant treatment by suicidal vs. nonsuicidal depressed patients

Journal of Affective Disorders

Volumn 122, Issue 1-2, 2010, Pages 154-158

  Pompili, Maurizio ^a,b   Baldessarini, Ross J ^b   Tondo, Leonardo ^b,c,d   Innamorati, Marco ^a,e   Tatarelli, Roberto ^a   Girardi, Paolo ^a   De Pisa, Eleonora ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF CAGLIARI   (Italy)

^d Lucio Bini Mood Disorders Research Center   (Italy)

^e UNIVERSITÀ EUROPEA DI ROMA   (Italy)

Author keywords

Depression; Intravenous antidepressants; Major affective disorders; Suicide; Treatment response

Indexed keywords

ANTIDEPRESSANT AGENT;

ADULT; ARTICLE; BIPOLAR DISORDER; CLINICAL FEATURE; CONTROLLED STUDY; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DISEASE SEVERITY; FEMALE; HAMILTON SCALE; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MORBIDITY; OUTPATIENT CARE; PRIORITY JOURNAL; SUICIDE ATTEMPT; TREATMENT DURATION; TREATMENT OUTCOME; TREATMENT RESPONSE;

ADMINISTRATION, ORAL; ADULT; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; ANTIMANIC AGENTS; BIPOLAR DISORDER; CITALOPRAM; COMORBIDITY; DAY CARE; DEPRESSIVE DISORDER, MAJOR; DRUG THERAPY, COMBINATION; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFUSIONS, INTRAVENOUS; ITALY; MALE; MIDDLE AGED; PERSONALITY INVENTORY; PROGNOSIS; PSYCHOMETRICS; RECURRENCE; SUICIDE; YOUNG ADULT;

EID: 77649181284     PISSN: 01650327     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jad.2009.07.018     Document Type: Article

References (36)

1. Acharya N., Rosen A.S., Polzer J.P., D'Souza D.N., Perahia D.G., Cavazzoni P.A., and Baldessarini R.J. Duloxetine: meta-analyses of suicidal behaviors and ideation in clinical trials for major depressive disorder. J. Clin. Psychopharmacol. 26 (2006) 587-594
2. Altamura A.C., Dell'Osso B., Buoli M., Zanoni S., and Mundo E. Intravenous augmentative citalopram versus clomipramine in partial/nonresponder depressed patients: a short-term, low dose, randomized, placebo-controlled study. J. Clin. Psychopharmacol. 28 (2008) 406-410
3. Baldessarini R.J., Pompili M., and Tondo L. Bipolar disorder. In: Simon R.I., and Hales R.E. (Eds). American Psychiatric Textbook of Suicide Assessment and Management (2006), American Psychiatric Publishing, Washington, DC 277-299
4. Baldessarini R.J., Pompili M., and Tondo L. Suicidal risk in antidepressant drug trials. Arch. Gen. Psychiatry 63 (2006) 246-248
5. Baldessarini R.J., and Tondo L. Lithium and suicidal risk. Bipolar Disord. 10 (2008) 114-115
6. Baldessarini R.J., and Tondo L. Meta-analytic comparison of antisuicidal effects of lithium versus anticonvulsants. Pharmacopsychiatry 42 (2009) 72-75
7. Baldessarini R.J., Tondo L., Strombom I.M., Dominguez S., Fawcett J., Licinio J., Oquendo M.A., Tollefson G.D., Valuck R.J., and Tohen M. Ecological studies of antidepressant treatment and suicidal risks. Harv. Rev. Psychiatry 15 (2007) 133-145
8. Barbui C., Esposito E., and Cipriani A. Selective serotonin reuptake inhibitors and risk of suicide: systematic review of observational studies. CMAJ 180 (2009) 291-297
9. Beasley Jr. C.M., Dornseif B.E., Bosomworth J.C., Sayler M.E., Rampey Jr. A.H., Heiligenstein J.H., Thompson V.L., Murphy D.J., and Masica D.N. Fluoxetine and suicide: a meta-analysis of controlled trials of treatment for depression. BMJ 303 (1991) 685-692
10. Fergusson D., Doucette S., Glass K.C., Shapiro S., Healy D., Hebert P., and Hutton B. Association between suicide attempts and selective serotonin reuptake inhibitors: systematic review of randomised controlled trials. BMJ 330 (2005) 396-402
11. Filteau M.J., Lapierre Y.D., Bakish D., and Blanchard A. Reduction in suicidal ideation with SSRIs: a review of 459 depressed patients. J. Psychiatry Neurosci. 18 (1993) 114-119
12. Goldberg J.F., Singer T.M., and Garno J.L. Suicidality and substance abuse in affective disorders. J. Clin. Psychiatry 62 Suppl. 25 (2001) 35-43
13. In: Goldsmith S.K., Pellmar T.C., Kleinman A.M., and Bunney W.E. (Eds). Reducing suicide: A national imperative (2002), Joseph Henry Press, Washington, D.C.
14. Guelfi J.D., Strub N., and Loft H. Efficacy of intravenous citalopram compared with oral citalopram for severe depression. Safety and efficacy data from a double-blind, double-dummy trial. J. Affect. Disord. 58 (2000) 201-209
15. Gunnell D., Saperia J., and Ashby D. Selective serotonin reuptake inhibitors (SSRIs) and suicide in adults: meta-analysis of drug company data from placebo controlled, randomised controlled trials submitted to the MHRA's safety review. BMJ 330 (2005) 385-389
16. Hamilton M. A Rating Scale for depression. J. Neurol. Neurosurg. Psychiatry 23 (1960) 56-62
17. Hennen J., and Baldessarini R.J. Suicidal risk during treatment with clozapine: a meta-analysis. Schizophr. Res. 73 (2005) 139-145
18. Jick H., Kaye J.A., and Jick S.S. Antidepressants and the risk of suicidal behaviors. JAMA 292 (2004) 338-343
19. Kasper S., and Muller-Spahn F. Intravenous antidepressant treatment: focus on citalopram. Eur. Arch. Psychiatry Clin. Neurosci. 252 (2002) 105-109
20. Khan A., Warner H.A., and Brown W.A. Symptom reduction and suicide risk in patients treated with placebo in antidepressant clinical trials: an analysis of the FDA database. Arch. Gen. Psychiatry 57 (2000) 311-317
21. Khan A., Khan S., Kolts R., and Brown W.A. Suicide rates in clinical trials of SSRIs, other antidepressants, and placebo: analysis of FDA reports. Am. J. Psychiatry 160 (2003) 790-792
22. Lapierre Y.D. Suicidality with selective serotonin reuptake inhibitors: Valid claim?. J. Psychiatry Neurosci. 28 (2003) 340-347
23. Malhotra K., Schwartz T., and Hameed U. Presence of suicidality as a prognostic indicator. J. Postgrad. Med. 50 (2004) 185-188
24. Martinez C., Rietbrock S., Wise L., Ashby D., Chick J., Moseley J., Evans S., and Gunnell D. Antidepressant treatment and the risk of fatal and non-fatal self harm in first episode depression: nested case-control study. BMJ 330 (2005) 389-394
25. Meltzer H.Y., Alphs L., Green A.I., Altamura A.C., Anand R., Bertoldi A., Bourgeois M., Chouinard G., Islam M.Z., Kane J., Krishnan R., Lindenmayer J.P., and Potkin S. Clozapine treatment for suicidality in schizophrenia: International Suicide Prevention Trial (InterSePT). Arch. Gen. Psychiatry 60 (2003) 82-91
26. Mulder R.T., Joyce P.R., Frampton C.M., and Luty S.E. Antidepressant treatment is associated with a reduction in suicidal ideation and suicide attempts. Acta Psychiatr. Scand. 118 (2008) 116-122
27. Pedersen A.G. Escitalopram and suicidality in adult depression and anxiety. Int. Clin. Psychopharmacol. 20 (2005) 139-143
28. Perlis R.H., Beasley Jr. C.M., Wines Jr. J.D., Tamura R.N., Cusin C., Shear D., Amsterdam J., Quitkin F., Strong R.E., Rosenbaum J.F., and Fava M. Treatment-associated suicidal ideation and adverse effects in an open, multicenter trial of fluoxetine for major depressive episodes. Psychother. Psychosom. 76 (2007) 40-46
29. Ravindran L., Jung S., and Ravindran A. Intravenous anti-obsessive agents: a review. J. Psychopharmacol. 21 (2008) Nov [Electronic publication ahead of print]
30. Sheehan D.V., Lecrubier Y., Sheehan K.H., Amorim P., Janavs J., Weiller E., Hergueta T., Baker R., and Dunbar G.C. The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J. Clin. Psychiatry 59 Suppl. 20 (1998) 22-33
31. Søndergard L., Kvist K., Andersen P.K., and Kessing L.V. Do antidepressants prevent suicide?. Int. Clin. Psychopharmacol. 21 (2006) 211-218
32. Stone M., Laughren T., Levenson M., Holland P.C., Hughes A., Hammad T.A., Temple R., and Rochester G.R. Risk of suicidality in clinical trials of antidepressants: analysis of proprietary data submitted to US Food and Drug Administration. BMJ 339 (2009) 1-10
33. Storosum J.G., van Zwieten B.J., van den Brink W., Gersons B.P., and Broekmans A.W. Suicide risk in placebo-controlled studies of major depression. Am. J. Psychiatry 158 (2001) 1271-1275
34. Szanto K., Mulsant B.H., Houck P.R., Dew M.A., Dombrovski A., Pollock B.G., and Reynolds III C.F. Emergence, persistence, and resolution of suicidal ideation during treatment of depression in old age. J. Affect. Disord. 98 (2007) 153-161
35. Tondo L., Lepri B., and Baldessarini R.J. Suicidal status during antidepressant treatment in 789 Sardinian patients with major affective disorder. Acta Psychiatr. Scand. 118 (2008) 106-115
36. U.S. Food and Drug Administration (FDA), 2009. Antidepressant use in children, adolescents, and adults. Accessed at http://www.fda.gov/Drugs/DrugSafety/InformationbyDrugClass/UCM096273 (accessed July 22, 2009).