-
1
-
-
47649115323
-
Life expectancy of individuals on combination antiretroviral therapy in high-income countries: A collaborative analysis of 14 cohort studies
-
The Antiretroviral Therapy Cohort Collaboration
-
The Antiretroviral Therapy Cohort Collaboration. Life expectancy of individuals on combination antiretroviral therapy in high-income countries: a collaborative analysis of 14 cohort studies. Lancet 2008;372:293-299
-
(2008)
Lancet
, vol.372
, pp. 293-299
-
-
-
2
-
-
33748116898
-
Mortality in the highly active antiretroviral therapy era: Changing causes of death and disease in the HIV outpatient study
-
Pallela FJ Jr, Baker RK, Moorman AC, et al. Mortality in the highly active antiretroviral therapy era: changing causes of death and disease in the HIV Outpatient Study. J Acquir Immune Defic Syndr 2006;43:27-34
-
(2006)
J Acquir Immune Defic Syndr
, vol.43
, pp. 27-34
-
-
Pallela Jr., F.J.1
Baker, R.K.2
Moorman, A.C.3
-
3
-
-
4644230820
-
The pharmacology and management of the vitamin K antagonists
-
Ansell J, Hirsh J, Poller L, et al. The pharmacology and management of the vitamin K antagonists. Chest 2004;126:204S-33S
-
(2004)
Chest
, vol.126
-
-
Ansell, J.1
Hirsh, J.2
Poller, L.3
-
4
-
-
33745433348
-
Lopinavir/ritonavir induces the hepatic activity of cytochrome P450 enzymes CYP2C9, CYP2C19, and CYP1A2 but inhibits the hepatic and intestinal activity of CYP3A as measured by a phenotyping drug cocktail in healthy volunteers
-
Lopinavir/ritonavir cocktail study examining cytochrome P450 enzyme interactions
-
Yeh RF, Gaver VE, Patterson KB, et al. Lopinavir/ritonavir induces the hepatic activity of cytochrome P450 enzymes CYP2C9, CYP2C19, and CYP1A2 but inhibits the hepatic and intestinal activity of CYP3A as measured by a phenotyping drug cocktail in healthy volunteers. J Acquir Immune Defic Syndr 2006;42:52-60 . Lopinavir/ritonavir cocktail study examining cytochrome P450 enzyme interactions.
-
(2006)
J Acquir Immune Defic Syndr
, vol.42
, pp. 52-60
-
-
Yeh, R.F.1
Gaver, V.E.2
Patterson, K.B.3
-
5
-
-
34249814621
-
Mechanisms of pharmacokinetic and pharmacodynamic drug interactions associated with ritonavir-enhanced tipranavir
-
Vourvahis M, Kashuba AD. Mechanisms of pharmacokinetic and pharmacodynamic drug interactions associated with ritonavir-enhanced tipranavir. Pharmacotherapy 2007;27:888-909
-
(2007)
Pharmacotherapy
, vol.27
, pp. 888-909
-
-
Vourvahis, M.1
Kashuba, A.D.2
-
6
-
-
60349115344
-
Cocktail study to investigate the in-vivo drug interaction potential of darunavir coadministered with low-dose ritonavir (DRV/r; RTV) on cytochrome P450 enzymes 2D6, 2C9 and 2C19
-
Presented at the New Orleans, USA, April
-
Sekar V, Spinosa-Guzman S, Meyvisch P, et al. Cocktail study to investigate the in-vivo drug interaction potential of darunavir coadministered with low-dose ritonavir (DRV/r; RTV) on cytochrome P450 enzymes 2D6, 2C9 and 2C19. Presented at the 9th International Workshop on Clinical Pharmacology of HIV (IWCPHIV), New Orleans, USA, April 7-9 2008
-
(2008)
9th International Workshop on Clinical Pharmacology of HIV (IWCPHIV)
, pp. 7-9
-
-
Sekar, V.1
Spinosa-Guzman, S.2
Meyvisch, P.3
-
7
-
-
45749145161
-
Possible antiretroviral therapy-warfarin drug interaction
-
Fulco PP, Zingone MM, Higginson RT. Possible antiretroviral therapy-warfarin drug interaction. Pharmacotherapy 2008;28:945-949
-
(2008)
Pharmacotherapy
, vol.28
, pp. 945-949
-
-
Fulco, P.P.1
Zingone, M.M.2
Higginson, R.T.3
-
8
-
-
0035951474
-
Need for increased dose of warfarin in HIV patients taking nevirapine
-
Dionisio D, Mininni S, Bartolozzi D, et al. Need for increased dose of warfarin in HIV patients taking nevirapine. AIDS 2001;15:277-278
-
(2001)
AIDS
, vol.15
, pp. 277-278
-
-
Dionisio, D.1
Mininni, S.2
Bartolozzi, D.3
-
9
-
-
39349087177
-
Drug interactions between warfarin and efavirenz or lopinavir-ritonavir in clinical treatment
-
Bonora S, Lanzafame M, D'Avolio A, et al. Drug interactions between warfarin and efavirenz or lopinavir-ritonavir in clinical treatment. Clin Infect Dis 2008;46:146-147
-
(2008)
Clin Infect Dis
, vol.46
, pp. 146-147
-
-
Bonora, S.1
Lanzafame, M.2
D'Avolio, A.3
-
10
-
-
0032492964
-
Influence of indinavir and ritonavir on warfarin anticoagulant activity
-
Gatti G, Alessandrini A, Camera M, et al. Influence of indinavir and ritonavir on warfarin anticoagulant activity. AIDS 1998;12:825-856
-
(1998)
AIDS
, vol.12
, pp. 825-856
-
-
Gatti, G.1
Alessandrini, A.2
Camera, M.3
-
11
-
-
0032425376
-
Potential interaction involving warfarin and ritonavir
-
Knoell KR, Young TM, Cousins ES. Potential interaction involving warfarin and ritonavir. Ann Pharmacother 1998;32:1299-1302
-
(1998)
Ann Pharmacother
, vol.32
, pp. 1299-1302
-
-
Knoell, K.R.1
Young, T.M.2
Cousins, E.S.3
-
12
-
-
34548355091
-
Interaction between lopinavir/ritonavir and warfarin
-
Hughes CA, Freitas A, Miedzinski LJ. Interaction between lopinavir/ritonavir and warfarin. CMAJ 2007;177:357-359
-
(2007)
CMAJ
, vol.177
, pp. 357-359
-
-
Hughes, C.A.1
Freitas, A.2
Miedzinski, L.J.3
-
13
-
-
0033397061
-
Ritonavir and warfarin interaction
-
Newshan G, Tsang P. Ritonavir and warfarin interaction. AIDS 1999;13:1788-1789
-
(1999)
AIDS
, vol.13
, pp. 1788-1789
-
-
Newshan, G.1
Tsang, P.2
-
14
-
-
0031008490
-
Hypoprothrombinemia during concomitant therapy with warfarin and saquinavir
-
Darlington MR. Hypoprothrombinemia during concomitant therapy with warfarin and saquinavir. Ann Pharmacother 1997;31:647
-
(1997)
Ann Pharmacother
, vol.31
, pp. 647
-
-
Darlington, M.R.1
-
15
-
-
47049117675
-
Venous thromboembolism in patients with HIV/AIDS a case-control study
-
Ahonkhai A, Gebo K, Streiff M, et al. Venous thromboembolism in patients with HIV/AIDS a case-control study. J Acquir Immune Defic Syndr 2008;48:310-314
-
(2008)
J Acquir Immune Defic Syndr
, vol.48
, pp. 310-314
-
-
Ahonkhai, A.1
Gebo, K.2
Streiff, M.3
-
16
-
-
0036251092
-
HIV infection is a risk factor for venous thromboembolism
-
Copur AS, Smith P, Gomez V, et al. HIV infection is a risk factor for venous thromboembolism. AIDS Patient Care STDS 2002;16:205-209
-
(2002)
AIDS Patient Care STDS
, vol.16
, pp. 205-209
-
-
Copur, A.S.1
Smith, P.2
Gomez, V.3
-
18
-
-
12844277984
-
Thrombotic complications in patients infected with HIV in the era of highly active antiretroviral therapy: A case series
-
Jacobson M, Dezube B, Aboulafia D. Thrombotic complications in patients infected with HIV in the era of highly active antiretroviral therapy: a case series. CID 2004;39:1214-1222
-
(2004)
CID
, vol.39
, pp. 1214-1222
-
-
Jacobson, M.1
Dezube, B.2
Aboulafia, D.3
-
19
-
-
55049100842
-
Inhibition and induction of human cytochrome P450 enzymes: Current status
-
Pelkonen O, Turpeinen M, Hakkola J, et al. Inhibition and induction of human cytochrome P450 enzymes: current status. Arch Toxicol 2008;82:667-715
-
(2008)
Arch Toxicol
, vol.82
, pp. 667-715
-
-
Pelkonen, O.1
Turpeinen, M.2
Hakkola, J.3
-
20
-
-
42949163382
-
Cytochrome P450 part 1: Multiplicity and function
-
McKinnon R, Sorich M, Ward M. Cytochrome P450 part 1: multiplicity and function. J Pharm Pract Res 2008;38:55-57
-
(2008)
J Pharm Pract Res
, vol.38
, pp. 55-57
-
-
Mc Kinnon, R.1
Sorich, M.2
Ward, M.3
-
22
-
-
58449087539
-
Pharmacogenomics of warfarin: Uncovering a piece of the warfarin mystery
-
Gulseth M, Grice G, Dager W. Pharmacogenomics of warfarin: uncovering a piece of the warfarin mystery. Am J Health Syst Pharm 2009;66:123-133
-
(2009)
Am J Health Syst Pharm
, vol.66
, pp. 123-133
-
-
Gulseth, M.1
Grice, G.2
Dager, W.3
-
23
-
-
0016220245
-
Studies on the optical enantiomorphs of warfarin in man
-
O'Reilly RA. Studies on the optical enantiomorphs of warfarin in man. Clin Pharmacol Ther 1974;16:348-354
-
(1974)
Clin Pharmacol Ther
, vol.16
, pp. 348-354
-
-
O'Reilly, R.A.1
-
24
-
-
0016374914
-
Pharmacokinetics and pharmacodynamics of the enantiomers of warfarin in man
-
Breckenridge A,OrmeM,WesselingH, et al. Pharmacokinetics and pharmacodynamics of the enantiomers of warfarin in man. Clin Pharmacol Ther 1974;15:424-430
-
(1974)
Clin Pharmacol Ther
, vol.15
, pp. 424-430
-
-
Breckenridge, A.1
Orme, M.2
Wesseling, H.3
-
25
-
-
0026519541
-
Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: A role for P-4502C9 in the etiology of (S)-warfarin-drug interactions
-
Rettie AE, Korzekwa KR, Kunze KL, et al. Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions. Chem Res Toxicol 1992;5:54-59
-
(1992)
Chem Res Toxicol
, vol.5
, pp. 54-59
-
-
Rettie, A.E.1
Korzekwa, K.R.2
Kunze, K.L.3
-
27
-
-
0028210729
-
Impaired (S)-warfarin metabolism catalysed by the R144C allelic variant of CYP2C9
-
Rettie AE, Wienkers LC, Gonzalez FJ, et al. Impaired (S)-warfarin metabolism catalysed by the R144C allelic variant of CYP2C9. Pharmacogenetics 1994;4:39-42
-
(1994)
Pharmacogenetics
, vol.4
, pp. 39-42
-
-
Rettie, A.E.1
Wienkers, L.C.2
Gonzalez, F.J.3
-
28
-
-
0030587544
-
Allelic variants of human cytochrome P450 2C9: Baculovirus-mediated expression, purification, structural characterization, substrate stereoselectivity, and prochiral selectivity of the wild-type and I359L mutant forms
-
Haining RL, Hunter AP, Veronese ME, et al. Allelic variants of human cytochrome P450 2C9: baculovirus-mediated expression, purification, structural characterization, substrate stereoselectivity, and prochiral selectivity of the wild-type and I359L mutant forms. Arch Biochem Biophys 1996;333:447-458
-
(1996)
Arch Biochem Biophys
, vol.333
, pp. 447-458
-
-
Haining, R.L.1
Hunter, A.P.2
Veronese, M.E.3
-
29
-
-
0030858832
-
The R144C change in the CYP2C9*2 allele alters interaction of the cytochrome P450 with NADPH: Cytochrome P450 oxidoreductase
-
Crespi CL, Miller VP. The R144C change in the CYP2C9*2 allele alters interaction of the cytochrome P450 with NADPH: cytochrome P450 oxidoreductase. Pharmacogenetics 1997;7:203-210
-
(1997)
Pharmacogenetics
, vol.7
, pp. 203-210
-
-
Crespi, C.L.1
Miller, V.P.2
-
30
-
-
1542346407
-
CYP2C9 genotypes and dose requirements during the induction phase of oral anticoagulant therapy
-
Peyvandi F, Spreafico M, Siboni SM, et al. CYP2C9 genotypes and dose requirements during the induction phase of oral anticoagulant therapy. Clin Pharmacol Ther 2004;75:198-203
-
(2004)
Clin Pharmacol Ther
, vol.75
, pp. 198-203
-
-
Peyvandi, F.1
Spreafico, M.2
Siboni, S.M.3
-
31
-
-
28144454744
-
Several-fold increase in risk of overanticoagulation by CYP2C9 mutations
-
Lindh JD, Lundgren S, Holm L, et al. Several-fold increase in risk of overanticoagulation by CYP2C9 mutations. Clin Pharmacol Ther 2005;78:540-550
-
(2005)
Clin Pharmacol Ther
, vol.78
, pp. 540-550
-
-
Lindh, J.D.1
Lundgren, S.2
Holm, L.3
-
32
-
-
3042575861
-
Warfarin dosing and cytochrome P450 2C9 polymorphisms
-
Joffe HV, Xu R, Johnson FB, et al. Warfarin dosing and cytochrome P450 2C9 polymorphisms. Thromb Haemost 2004;91:1123-1128
-
(2004)
Thromb Haemost
, vol.91
, pp. 1123-1128
-
-
Joffe, H.V.1
Xu, R.2
Johnson, F.B.3
-
33
-
-
31344451857
-
Different contributions of polymorphisms in VKORC1 and CYP2C9 to intra- and inter-population differences in maintenance dose of warfarin in Japanese, Caucasians and African-Americans
-
Takahashi H, Wilkinson GR, Nutescu EA, et al. Different contributions of polymorphisms in VKORC1 and CYP2C9 to intra- and inter-population differences in maintenance dose of warfarin in Japanese, Caucasians and African-Americans. Pharmacogenet Genomics 2006;16:101-110
-
(2006)
Pharmacogenet Genomics
, vol.16
, pp. 101-110
-
-
Takahashi, H.1
Wilkinson, G.R.2
Nutescu, E.A.3
-
34
-
-
33645849823
-
Influence of coagulation factor, vitamin K epoxide reductase complex subunit 1, and cytochromeP4502C9genepolymorphisms on warfarin dose requirements
-
Aquilante CL, Langaee TY, LopezLM,et al. Influence of coagulation factor, vitamin K epoxide reductase complex subunit 1, and cytochromeP4502C9genepolymorphisms on warfarin dose requirements. Clin Pharmacol Ther 2006;79:291-302
-
(2006)
Clin Pharmacol Ther
, vol.79
, pp. 291-302
-
-
Aquilante, C.L.1
Langaee, T.Y.2
Lopez, L.M.3
-
36
-
-
85069121563
-
-
Human Cytochrome P450 Allele Nomenclature Committee. Available from URL[Accessed 1 September 2009]
-
Human Cytochrome P450 Allele Nomenclature Committee. Available from URL: http://www.cypalleles.ki.se/cyp2c9. htm. [Accessed 1 September 2009]
-
-
-
-
38
-
-
84868908453
-
-
Available from URL[Accessed 1 September 2009]
-
Tseng A, Chionglo M. Selected properties of maraviroc. Available from URL: http:// www.hivclinic.ca/main/ drugs-properties-files/CCR5-maraviroc. pdf. [Accessed 1 September 2009]
-
Selected Properties of Maraviroc
-
-
Tseng, A.1
Chionglo, M.2
-
39
-
-
0031931102
-
Protease inhibitors as inhibitors of human cytochromes P450: High risk associated with ritonavir
-
Von Moltke LL, Greenblatt DJ, Grassi JM, et al. Protease inhibitors as inhibitors of human cytochromes P450: high risk associated with ritonavir. J Clin Pharmacol 1998;38:106-111
-
(1998)
J Clin Pharmacol
, vol.38
, pp. 106-111
-
-
Von Moltke, L.L.1
Greenblatt, D.J.2
Grassi, J.M.3
-
40
-
-
0034747669
-
Inhibition of humancytochrome P450 isoforms by nonnucleoside reverse transcriptase inhibitors
-
Von MoltkeLL,GreenblattDJ,GrandaBW, et al. Inhibition of humancytochrome P450 isoforms by nonnucleoside reverse transcriptase inhibitors. J Clin Pharmacol 2001;41:85-91
-
(2001)
J Clin Pharmacol
, vol.41
, pp. 85-91
-
-
Von Moltke, L.L.1
Greenblatt, D.J.2
Granda, B.W.3
-
41
-
-
34748887980
-
Cytochrome P450 enzymes and transporters induced by anti-human immunodeficiency virus protease inhibitors in human hepatocytes: Implications for predicting clinical drug interactions
-
[Epub 16 July 2007]
-
Dixit V, Hariparsad N, Li F, et al. Cytochrome P450 enzymes and transporters induced by anti-human immunodeficiency virus protease inhibitors in human hepatocytes: implications for predicting clinical drug interactions. Drug Metab Dispos 2007;35:1853-1859 [Epub 16 July 2007]
-
(2007)
Drug Metab Dispos
, vol.35
, pp. 1853-1859
-
-
Dixit, V.1
Hariparsad, N.2
Li, F.3
-
42
-
-
84855616052
-
-
Panel on Antiretroviral Guidelines for Adult and Adolescents. Department of Health and Human Services. November 3, Available from[Accessed 1 September 2009]
-
Panel on Antiretroviral Guidelines for Adult and Adolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Department of Health and Human Services. November 3, 2008;1-139. Available from: http://www.aidsinfo.nih. gov/ContentFiles/AdultandAdolescentGL. pdf. [Accessed 1 September 2009]
-
(2008)
Guidelines for the Use of Antiretroviral Agents in HIV-1-infected Adults and Adolescents
, pp. 1-139
-
-
-
43
-
-
33747861061
-
Pharmacokinetic drug interactions with non-nucleoside reverse transcriptase inhibitors
-
Ma Q, Okusanya OO, Smith PF, et al. Pharmacokinetic drug interactions with non-nucleoside reverse transcriptase inhibitors. Expert Opin Drug Metab Toxicol 2005;1:473-485
-
(2005)
Expert Opin Drug Metab Toxicol
, vol.1
, pp. 473-485
-
-
Ma, Q.1
Okusanya, O.O.2
Smith, P.F.3
-
49
-
-
0344404144
-
Evaluation of the pharmacokinetic interactions between phenytoin and nelfinavir in healthy volunteers at steady state (abstract 426)
-
Presented at: Toronto, September
-
Shelton M, Cloen D, Becker M, et al. Evaluation of the pharmacokinetic interactions between phenytoin and nelfinavir in healthy volunteers at steady state (abstract 426). Presented at: 40th Interscience Conference on Antimicrobial Agents and Chemotherapy, Toronto, September 17-20, 2000
-
(2000)
40th Interscience Conference on Antimicrobial Agents and Chemotherapy
, pp. 17-20
-
-
Shelton, M.1
Cloen, D.2
Becker, M.3
-
50
-
-
0032983746
-
A generalized seizure following initiation of nelfinavir in a patient with human immunodeficiency virus type i infection, suspected due to interaction between nelfinavir and phenytoin
-
Honda M, Yasuoka A, Aoki M, Oka S. A generalized seizure following initiation of nelfinavir in a patient with human immunodeficiency virus type I infection, suspected due to interaction between nelfinavir and phenytoin. Intern Med 1999;38:302-303
-
(1999)
Intern Med
, vol.38
, pp. 302-303
-
-
Honda, M.1
Yasuoka, A.2
Aoki, M.3
Oka, S.4
-
51
-
-
0030430035
-
Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes
-
Kumar GN, Rodrigues AD, Buko AM, Denissen JF. Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes. J Pharmacol Exp Ther 1996;277:423-431
-
(1996)
J Pharmacol Exp Ther
, vol.277
, pp. 423-431
-
-
Kumar, G.N.1
Rodrigues, A.D.2
Buko, A.M.3
Denissen, J.F.4
-
52
-
-
0030852009
-
Differential inhibition of cytochrome P450 isoforms by the protease inhibitors, ritonavir, saquinavir and indinavir
-
Eagling VA, Back DJ, Barry MG. Differential inhibition of cytochrome P450 isoforms by the protease inhibitors, ritonavir, saquinavir and indinavir. Br J Clin Pharmacol 1997;44:190-194
-
(1997)
Br J Clin Pharmacol
, vol.44
, pp. 190-194
-
-
Eagling, V.A.1
Back, D.J.2
Barry, M.G.3
-
54
-
-
65549104789
-
-
Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, June
-
Product information. Aptivus (tipranavir). Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, June 2008
-
(2008)
Product Information. Aptivus (Tipranavir)
-
-
-
55
-
-
85069126338
-
-
Princeton, NJ: Bristo-Myers Squibb Company, November
-
Product information. Reyataz (atazanavir). Princeton, NJ: Bristo-Myers Squibb Company, November 2009
-
(2009)
Product Information. Reyataz (Atazanavir)
-
-
-
56
-
-
85069123480
-
-
Research Triangle Park, NC: GlaxoSmithKline, September
-
Product information. Lexiva (fosamprenavir). Research Triangle Park, NC: GlaxoSmithKline, September 2009
-
(2009)
Product Information. Lexiva (Fosamprenavir)
-
-
-
57
-
-
85069124224
-
-
Whitehouse Station, NJ: Merck and Company, Inc., October
-
Product information. Crixivan (indinavir). Whitehouse Station, NJ: Merck and Company, Inc., October 2008
-
(2008)
Product Information. Crixivan (Indinavir)
-
-
-
59
-
-
10044225576
-
Lower frequency of CYP2C9*2 in Mexican-Americans compared to Spaniards
-
LLerena A, Dorado P, O'Kirwan F, et al. Lower frequency of CYP2C9*2 in Mexican-Americans compared to Spaniards. Pharmacogenomics J 2004;4:403-406
-
(2004)
Pharmacogenomics J
, vol.4
, pp. 403-406
-
-
Llerena, A.1
Dorado, P.2
O'Kirwan, F.3
-
60
-
-
42449136621
-
Dosing algorithm for warfarin using CYP2C9 and VKORC1 genotyping from a multi-ethnic population:Comparisonwithother equations
-
Wu A, Wang P, Smith A, et al. Dosing algorithm for warfarin using CYP2C9 and VKORC1 genotyping from a multi-ethnic population:comparisonwithother equations. Pharmacogenomics 2008;9:169-178
-
(2008)
Pharmacogenomics
, vol.9
, pp. 169-178
-
-
Wu, A.1
Wang, P.2
Smith, A.3
-
61
-
-
4243369572
-
Frequency of the defective CYP2C9 variant alleles in different ethnic groups
-
Xie H, Prasad H, Landau R, et al. Frequency of the defective CYP2C9 variant alleles in different ethnic groups. Clin Pharmacol Ther 2002;71:P102
-
(2002)
Clin Pharmacol Ther
, vol.71
-
-
Xie, H.1
Prasad, H.2
Landau, R.3
|