Fatal cystic change of brain metastasis after response to gefitinib in non-small-cell lung cancer

Journal of Clinical Oncology

Volumn 27, Issue 30, 2009, Pages

  Zee, Ying Kiat ^a   Chin, Tan Min ^a   Wong, Alvin S C ^a  

^a NATIONAL UNIVERSITY HEALTH SYSTEM   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

GEFITINIB; STEROID;

ADD ON THERAPY; ADULT; ARTICLE; BLOOD SAMPLING; BRAIN HEMORRHAGE; BRAIN METASTASIS; BRAIN TUMOR; CANCER RADIOTHERAPY; CASE REPORT; CLINICAL EVALUATION; COMPUTER ASSISTED TOMOGRAPHY; CRANIECTOMY; DIZZINESS; DRUG EFFICACY; DRUG MEGADOSE; HEADACHE; HUMAN; LUNG BIOPSY; LUNG METASTASIS; LUNG NON SMALL CELL CANCER; MALE; NEUROIMAGING; NEUROLOGIC DISEASE; NEUROSURGERY; PRIORITY JOURNAL; TREATMENT OUTCOME; TREATMENT RESPONSE; TUMOR LOCALIZATION; TUMOR VOLUME;

ANTINEOPLASTIC AGENTS; BRAIN DISEASES; BRAIN NEOPLASMS; CARCINOMA, NON-SMALL-CELL LUNG; CYSTS; FATAL OUTCOME; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; QUINAZOLINES; TOMOGRAPHY, X-RAY COMPUTED;

EID: 77649140355     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2009.22.4501     Document Type: Article

References (5)

1. Katz A, Zalewski P: Quality-of-life benefits and evidence of antitumour activity for patients with brain metastases treated with gefitinib. Br J Cancer 89:S15-S18, 2003 (suppl 2)
2. Ma S, Xu Y, Deng Q, et al: Treatment of brain metastasis from non-small-cell lung cancer with whole brain radiotherapy and gefitinib in a Chinese population. Lung Cancer 65:198-203, 2009
3. Hotta K, Kiura K, Ueoka H, et al: Effect of gefitinib ('Iressa', ZD1839) on brain metastases in patients with advanced non-small-cell lung cancer. Lung Cancer 46:255-261, 2004
4. Ceresoli GL, Cappuzzo F, Gregorc V, et al: Gefitinib in patients with brain metastases from non-small-cell lung cancer: A prospective trial. Ann Oncol 15:1042-1047, 2004
5. Wu C, Li YL, Wang ZM, et al: Gefitinib as palliative therapy for lung adenocarcinoma metastatic to the brain. Lung Cancer 57:359-364, 2007