When is a fracture healed? Radiographic and clinical criteria revisited

Journal of Orthopaedic Trauma

Volumn 24, Issue SUPPL. 1, 2010, Pages

  Dijkman, Bernadette G ^a   Sprague, Sheila ^a   Schemitsch, Emil H ^b   Bhandari, Mohit ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b ST MICHAEL'S HOSPITAL   (Canada)

Author keywords

Clinical assessment; Clinical trails; Fracture healing; Radiographic review

Indexed keywords

AMALGAM;

BONE RADIOGRAPHY; CLINICAL ASSESSMENT; CONVALESCENCE; FRACTURE HEALING; HUMAN; MEDICAL DECISION MAKING; OUTCOME ASSESSMENT; PRIORITY JOURNAL; QUALITY OF LIFE; RELIABILITY; REVIEW; RIGIDITY; VALIDITY; WEIGHT BEARING;

FRACTURE HEALING; FRACTURES, BONE; HUMANS; PROGNOSIS; RADIOGRAPHY;

EID: 77649134915     PISSN: 08905339     EISSN: None     Source Type: Journal    
DOI: 10.1097/BOT.0b013e3181ca3f97     Document Type: Review

References (50)

1. Morshed S, Corrales L, Genant H, et al. Outcome assessment in clinical trials of fracture-healing. J Bone Joint Surg Am. 2008;90:62-67.
2. Bhandari M, Guyatt GH, Swiontkowski MF, et al. A lack of consensus in the assessment of fracture healing among orthopaedic surgeons. J Orthop Trauma. 2002;16:562-566.
3. Corrales LA, Morshed S, Bhandari M, et al. Variability in the assessment of fracture-healing in orthopaedic trauma studies. J Bone Joint Surg Am. 2008;90:1862-1868.
4. Markel MD, Bogdanske JJ, Xiang Z, et al. Atrophic nonunion can be predicted with dual energy x-ray absorptiometry in a canine ostectomy model. J Orthop Res. 1995;13:869-875.
5. Aro HT, Wippermann BW, Hodgson SF, et al. Prediction of properties of fracture callus by measurement of mineral density using micro-bone densitometry. J Bone Joint Surg Am. 1989;71:1020-1030.
6. Smith MA, Jones EA, Strachan RK, et al. Prediction of fracture healing in the tibia by quantitative radionuclide imaging. J Bone Joint Surg Br. 1987; 69:441-447
7. Moed BR, Watson JT, Goldschmidt P, et al. Ultrasound for the early diagnosis of fracture healing after interlocking nailing of the tibia without reaming. Clin Orthop Relat Res. 1995;310:137-144.
8. Braunstein EM, Goldstein SA, Ku J, et al. Computed tomography and plain radiography in experimental fracture healing. Skeletal Radiol. 1986; 15:27-31.
9. Schnarkowski P, Rédie J, Peterfy CG, et al. Tibial shaft fractures: assessment of fracture healing with computed tomography. J Comput Assist Tomogr. 1995;19:777-781.
10. Kalpakcioglu BB, Morshed S, Engelke K, et al. Advanced imaging of bone macrostructure and microstructure in bone fragility and fracture repair. J Bone Joint Surg Am. 2008;90:68-78.
11. Majumdar S. Magnetic resonance imaging of trabecular bone structure. Top Magn Reson Imaging. 2002;13:323-334.
12. Hipp JA, Jansujwicz A, Simmons CA, et al. Trabecular bone morphology from micro-magnetic resonance imaging. J Bone Miner Res. 1996;11: 286-297.
13. Wehrli FW, Hwang SN, Ma J, et al. Cancellous bone volume and structure in the forearm: noninvasive assessment with MR microimaging and image processing. Radiology. 1998;206:347-357
14. Whelan DB, Bhandari M, McKee MD, et al. Interobserver and intraobserver variation in the assessment of the healing of tibial fractures after intramedullary fixation. J Bone Joint Surg Br. 2002;84:15-18.
15. Hammer RR, Hammerby S, Lindholm B. Accuracy of radiologic assessment of tibial shaft fracture union in humans. Clin Orthop Relat Res. 1985;199:233-238.
16. Claes L, Grass R, Schmickal T, et al. Monitoring and healing analysis of 100 tibial shaft fractures. Langenbecks Arch Surg. 2002;387: 146-152.
17. McClelland D, Thomas PD, Bancroft G, et al. Fracture healing assessment comparing stiffness measurements using radiographs. Clin Orthop Relat Res. 2007;457:214-219.
18. Aranzulla PJ, Muckle DS, Cunningham JL. A portable monitoring system for measuring weight-bearing during tibial fracture healing. Med Eng Phys. 1998;20:543-548.
19. Kershaw CJ, Cunningham JL, Kenwright J. Tibial external fixation, weight bearing, and fracture movement. Clin Orthop Relat Res. 1993;293: 28-36.
20. Joslin CC, Eastaugh-Waring SJ, Hardy JR, et al. Weight bearing after tibial fracture as a guide to healing. Clin Biomech. 2008;23:329-333.
21. Goodship AE, Kenwright J. The influence of induced micromovement upon the healing of experimental tibial fractures. J Bone Joint Surg Br. 1985;67:650-655.
22. Kenwright J, Richardson JB, Cunningham JL, et al. Axial movement and tibial fractures. A controlled randomised trial of treatment. J Bone Joint Surg Br. 1991;73:654-659.
23. Benirschke SK, Mirels H, Jones D, et al. The use of resonant frequency measurements for the noninvasive assessment of mechanical stiffness of the healing tibia. J Orthop Trauma. 1993;7:64-71.
24. Saha S, Lakes RS. The effect of soft tissue on wave-propagation and vibration tests for determining the in vivo properties of bone. J Biomech. 1977;10:393-401.
25. Tower SS, Beals RK, Duwelius PJ. Resonant frequency analysis of the tibia as a measure of fracture healing. J Orthop Trauma. 1993;7: 552-557.
26. Evans M, Kenwright J, Cunningham JL. Design and performance of a fracture monitoring transducer. J Biomed Eng. 1988;10:64-69.
27. Edholm P, Hammer R, Hammerby S, et al. The stability of union in tibial shaft fractures: its measurement by a non-invasive method. Arch Orthop Trauma Surg. 1984;102:242-247.
28. Penzkofer R, Maier M, Nolte A, et al. Influence of intramedullary nail diameter and locking mode on the stability of tibial shaft fracture fixation. Arch Orthop Trauma Surg. 2009;129:525-31.
29. Hansen M, Mehler D, Hessmann MH, et al. Intramedullary stabilization of extraarticular proximal tibial fractures: a biomechanical comparison of intramedullary and extramedullary implants including a new proximal tibia nail (PTN). J Orthop Trauma. 2007;21:701-709.
30. Wade RH, Moorcroft CI, Thomas PB. Fracture stiffness as a guide to the management of tibial fractures. J Bone Joint Surg Br. 2001;83: 533-535.
31. Beaton DE, Schemitsch E. Measures of health-related quality of life and physical function. Clin Orthop Relat Res. 2003;413:90-105.
32. Agel J, Swiontkowski MF. Guide to outcomes instruments for musculoskeletal trauma research. J Orthop Trauma. 2006;20:S65-146.
33. SF-36.org: a community for measuring health outcomes using SF tools. http://www.sf-36.org. Accessed December 5, 2008.
34. Bhandari M, Sprague S, Hanson B et al. Health-related quality of life following operative treatment of unstable ankle fractures: a prospective observational study. J Orthop Trauma. 2004;18:338-345.
35. Study to Prospectively Evaluate Reamed Intramedullary Nails in Patients with Tibial Fractures Investigators, Bhandari M, Guyatt G, Tornetta P 3rd, et al. Randomized trial of reamed and unreamed intramedullary nailing of tibial shaft fractures. J Bone Joint Surg Am. 2008;90:2567-2578.
36. The DASH outcome measure: disabilities of the arm, shoulder, and hand. http://www.dash.iwh.on.ca/. Accessed December 5, 2008.
37. Bellamy N. WOMAC: a 20-year experiential review of a patient-centered self-reported health status questionnaire. J Rheumatol. 2002;29:2473-2476.
38. Health-related Health Utilities Group/Health Utilities Index (HUG/HUI) quality of life research. http://www.fhs.mcmaster.ca/hug. Accessed December 5, 2008.
39. Feeny D, Furlong W, Torrance GW, et al. Multiattribute and single-attribute utility functions for the health utilities index mark 3 system. Med Care. 2002;40:113-128.
40. Furlong WJ, Feeny DH, Torrance GW, et al. The Health Utilities Index (HUI) system for assessing health-related quality of life in clinical studies. Ann Med. 2001;33:375-384.
41. Torrance GW, Feeny DH, Furlong WJ, et al. Multiattribute utility function for a comprehensive health status classification system. Health Utilities Index Mark 2. Med Care. 1996;34:702-722.
42. Hudak PL, Wright JG. The characteristics of patient satisfaction measures. Spine. 2000;25:3167-3177.
43. Aharony L, Strasser S. Patient satisfaction: what we know about and what we still need to explore. Med Care Rev. 1993;50:49-79.
44. Lochman JE. Factors related to patients' satisfaction with their medical care. J Community Health. 1983;9:91-109.
45. Lerner D, Amick BC 3rd, Rogers WH, et al. The Work Limitations Questionnaire. Med Care. 2001;39:72-85.
46. Lerner D, Reed JI, Massarotti E, et al. The Work Limitations Questionnaire's validity and reliability among patients with osteoarthritis. J Clin Epidemiol. 2002;55:197-208.
47. Karanicolas PJ, Bhandari M, Taromi B, et al. Blinding of outcomes in trials of orthopaedic trauma: an opportunity to enhance the validity of clinical trials. J Bone Joint Surg Am. 2008;90:1026-1033.
48. Poolman RW, Struijs PA, Krips R, et al. Reporting of outcomes in orthopaedic randomized trials: does blinding of outcome assessors matter? J Bone Joint Surg Am. 2007;89:550-558.
49. Cook D, Walter S, Freitag A, et al. Adjudicating ventilator-associated pneumonia in a randomized trial of critically ill patients. J Crit Care. 1998;13:159-163.
50. Granger CB, Vogel V, Cummings SR, et al. Do we need to adjudicate major clinical events? Clin Trials. 2008;5:56-60.