Fibromyalgia: Current diagnosis and management

Expert Review of Clinical Immunology

Volumn 5, Issue 2, 2009, Pages 181-192

  Guymer, Emma ^a   Littlejohn, Geoffrey ^b  

^a MONASH MEDICAL CENTRE   (Australia)

^b MONASH UNIVERSITY   (Australia)

Author keywords

Fatigue; Fibromyalgia; Fibromyalgia syndrome; Muscle pain; Psychological distress; Stiffness; Stress

Indexed keywords

AMITRIPTYLINE; ANALGESIC AGENT; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; CYCLOBENZAPRINE; DEXTROMETHORPHAN; DULOXETINE; FLUOXETINE; GABAPENTIN; KETAMINE; MILNACIPRAN; MOCLOBEMIDE; MONOAMINE OXIDASE INHIBITOR; NONSTEROID ANTIINFLAMMATORY AGENT; OPIATE; PARACETAMOL; PRAMIPEXOLE; PREGABALIN; SEROTONIN ANTAGONIST; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; TRAMADOL; TRICYCLIC ANTIDEPRESSANT AGENT; TROPISETRON; VENLAFAXINE;

ANXIETY; CHRONIC FATIGUE SYNDROME; CLINICAL FEATURE; COGNITIVE DEFECT; COMORBIDITY; CONSTIPATION; DIZZINESS; DYSESTHESIA; EMOTIONAL STRESS; EXERCISE; FATIGUE; FIBROMYALGIA; HEADACHE; HUMAN; IRRITABLE COLON; MOOD DISORDER; MUSCLE STIFFNESS; NAUSEA; NEUROPHYSIOLOGY; PAIN; PATIENT EDUCATION; PSYCHOTHERAPY; RESTLESS LEGS SYNDROME; REVIEW; SLEEP DISORDER; SOMNOLENCE; TRANSCRANIAL MAGNETIC STIMULATION; XEROSTOMIA;

EID: 77649131961     PISSN: 1744666X     EISSN: None     Source Type: Journal    
DOI: 10.1586/1744666X.5.2.181     Document Type: Review

References (77)

1. Wolfe F, Smythe HA, Yunus MB et al. The American College of Rheumatology 1990 criteria for the classification of fibromyalgia. Report of the Multicenter Criteria Committee. Arthritis Rheum. 33(2), 160-172 (1990).
2. Buskila D, Press J, Gedalia A et al. Assessment of nonarticular tenderness and prevalence of fibromyalgia in children. J. Rheumatol. 20(2), 368-370 (1993). (Pubitemid 23066054)
3. Wolfe F, Ross K, Anderson J, Russell IJ, Hebert L. The prevalence and characteristics of fibromyalgia in the general population. Arthritis Rheum. 38(1), 19-28 (1995).
4. Carmona L, Ballina J, Gabriel R, Laffon A. The burden of musculoskeletal diseases in the general population of Spain: results from a national survey. Ann. Rheum. Dis. 60(11), 1040-1045 (2001).
5. White KP, Speechley M, Harth M, Ostbye T. The London Fibromyalgia Epidemiology Study: comparing the demographic and clinical characteristics in 100 random community cases of fibromyalgia versus controls. J. Rheumatol. 26(7), 1577-1585 (1999). (Pubitemid 29317883)
6. McBeth J, Jones K. Epidemiology of chronic musculoskeletal pain. Best Pract. Res. Clin. Rheumatol. 21(3), 403-425 (2007).
7. Farooqi A, Gibson T. Prevalence of the major rheumatic disorders in the adult population of north Pakistan. Br. J. Rheumatol. 37(5), 491-495 (1998).
8. Hoffman DL, Dukes EM. The health status burden of people with fibromyalgia: a review of studies that assessed health status with the SF-36 or the SF-12. Int. J. Clin. Pract. 62(1), 115-126 (2008).
9. Berger A, Dukes E, Martin S, Edelsberg J, Oster G. Characteristics and healthcare costs of patients with fibromyalgia syndrome. Int. J. Clin. Pract. 61(9), 1498-1508 (2007).
10. Bennett RM, Jones J, Turk DC, Russell IJ, Matallana L. An internet survey of 2,596 people with fibromyalgia. BMC Musculoskelet. Disord. 8, 27 (2007).
11. Strusberg I, Mendelberg RC, Serra HA, Strusberg AM. Influence of weather conditions on rheumatic pain. J. Rheumatol. 29(2), 335-338 (2002).
12. Yunus M. Symptoms and signs of fibromyalgia syndrome: an overview. In: Fibromyalgia and Other Central Syndromes. Wallace DJ (Ed.). Lippincott Williams and Wilkins, PA, USA 125-132 (2005).
13. Guymer EK, Clauw DJ. Treatment of fatigue in fibromyalgia. Rheum. Dis. Clin. North Am. 28(2), 367-378 (2002).
14. Anch AM, Lue FA, MacLean AW, Moldofsky H. Sleep physiology and psychological aspects of the fibrositis (fibromyalgia) syndrome. Can. J. Psychol. 45(2), 179-184 (1991).
15. Moldofsky H, Alvarez-Horine S. Disordered sleep and sleep-related daytime functioning in fibromyalgia syndrome. Program of Abstracts of the Annual European League Against Rheumatism Congress, Paris, France (2008) (Abstract 380).
16. Wolfe F. The relation between tender points and fibromyalgia symptom variables: evidence that fibromyalgia is not a discrete disorder in the clinic. Ann. Rheum. Dis. 56(4), 268-271 (1997).
17. Granges G, Littlejohn GO. A comparative study of clinical signs in fibromyalgia/ fibrositis syndrome, healthy and exercising subjects. J. Rheumatol. 20(2), 344-351 (1993).
18. Yunus MB, Aldag JC. Restless legs syndrome and leg cramps in fibromyalgia syndrome: a controlled study. BMJ 312(7042), 1339 (1996).
19. Epstein SA, Kay G, Clauw D et al. Psychiatric disorders in patients with fibromyalgia. A multicenter investigation. Psychosomatics 40(1), 57-63 (1999).
20. Arnold LM, Hudson JI, Hess EV et al. Family study of fibromyalgia. Arthritis Rheum. 50(3), 944-952 (2004).
21. Arnold LM, Hudson JI, Keck PE, Auchenbach MB, Javaras KN, Hess EV. Comorbidity of fibromyalgia and psychiatric disorders. J. Clin. Psychiatry 67(8), 1219-1225 (2006).
22. Malt EA, Berle JE, Olafsson S, Lund A, Ursin H. Fibromyalgia is associated with panic disorder and functional dyspepsia with mood disorders. A study of women with random sample population controls. J. Psychosom. Res. 49(5), 285-289 (2000).
23. Buskila D, Cohen H. Comorbidity of fibromyalgia and psychiatric disorders. Curr. Pain Headache Rep. 11(5), 333-338 (2007).
24. Staud R. Biology and therapy of fibromyalgia: pain in fibromyalgia syndrome. Arthritis Res. Ther. 8(3), 208 (2006).
25. Russell IJ, Orr MD, Littman B et al. Elevated cerebrospinal fluid levels of substance P in patients with the fibromyalgia syndrome. Arthritis Rheum. 37(11), 1593-1601 (1994).
26. Nielsen LA, Henriksson KG. Pathophysiological mechanisms in chronic musculoskeletal pain (fibromyalgia): the role of central and peripheral sensitization and pain disinhibition. Best Pract. Res. Clin. Rheumatol. 21(3), 465-480 (2007).
27. Suzuki R, Rygh LJ, Dickenson AH. Bad news from the brain: descending 5-HT pathways that control spinal pain processing. Trends Pharmacol. Sci. 25(12), 613-617 (2004).
28. Buskila D, Neumann L. Fibromyalgia syndrome (FM) and nonarticular tenderness in relatives of patients with FM. J. Rheumatol. 24(5), 941-944 (1997). (Pubitemid 27223632)
29. Buskila D, Sarzi-Puttini P, Ablin JN. The genetics of fibromyalgia syndrome. Pharmacogenomics 8(1), 67-74 (2007).
30. Diatchenko L, Slade GD, Nackley AG et al. Genetic basis for individual variations in pain perception and the development of a chronic pain condition. Hum. Mol. Genet. 14(1), 135-143 (2005).
31. Gursoy S, Erdal E, Herken H, Madenci E, Alasehirli B, Erdal N. Significance of catechol-O-methyltransferase gene polymorphism in fibromyalgia syndrome. Rheumatol. Int. 23(3), 104-107 (2003). (Pubitemid 36712983)
32. Annemans L, Wessely S, Spaepen E et al. Health economic consequences related to the diagnosis of fibromyalgia syndrome. Arthritis Rheum. 58(3), 895-902 (2008).
33. Clauw DJ. Fibromyalgia: update on mechanisms and management. J. Clin. Rheumatol. 13(2), 102-109 (2007).
34. Sandstrom MJ, Keefe FJ. Self-management of fibromyalgia: the role of formal coping skills training and physical exercise training programs. Arthritis Care Res. 11(6), 432-447 (1998).
35. Buckelew SP, Huyser B, Hewett JE et al. Self-efficacy predicting outcome among fibromyalgia subjects. Arthritis Care Res. 9(2), 97-104 (1996).
36. Carville SF, Arendt-Nielsen S, Bliddal H et al. EULAR evidence based recommendations for the management of fibromyalgia syndrome. Ann. Rheum. Dis. 67, 536-541 (2008).
37. Busch AJ, Barber KA, Overend TJ, Peloso PM, Schachter CL. Exercise for treating fibromyalgia syndrome. Cochrane Database Syst. Rev. 4, CD003786 (2007).
38. Mannerkorpi K, Henriksson C. Non-pharmacological treatment of chronic widespread musculoskeletal pain. Best Pract. Res. Clin. Rheumatol. 21(3), 513-534 (2007).
39. Goldenberg DL, Burckhardt C, Crofford L. Management of fibromyalgia syndrome. JAMA 292(19), 2388-2395 (2004).
40. Rossy LA, Buckelew SP, Dorr N et al. A meta-analysis of fibromyalgia treatment interventions. Ann. Behav. Med. 21(2), 180-191 (1999).
41. Sewitch MJ, Dobkin PL, Bernatsky S et al. Medication non-adherence in women with fibromyalgia. Rheumatology (Oxf.) 43(5), 648-654 (2004).
42. Harris RE, Clauw DJ, Scott DJ, McLean SA, Gracely RH, Zubieta JK. Decreased central μ-opioid receptor availability in fibromyalgia. J. Neurosci. 27(37), 10000-10006 (2007).
43. Russell IJ, Kamin M, Bennett RM, Schnitzer TJ, Green JA, Katz WA. Efficacy of tramadol in treatment of pain in fibromyalgia. J. Clin. Rheumatol. 6(5), 250-257 (2000).
44. Bennett RM, Kamin M, Karim R, Rosenthal N. Tramadol and acetaminophen combination tablets in the treatment of fibromyalgia pain: a double-blind, randomized, placebo-controlled study. Am. J. Med. 114(7), 537-545 (2003). (Pubitemid 36577256)
45. Wolfe F, Zhao S, Lane N. Preference for nonsteroidal antiinflammatory drugs over acetaminophen by rheumatic disease patients: a survey of 1,799 patients with osteoarthritis, rheumatoid arthritis, and fibromyalgia. Arthritis Rheum. 43(2), 378-385 (2000).
46. Clauw DJ. Fibromyalgia. In: Rheumatology (4th ESdition). Hochberg MC, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH (Eds). Mosby-Elsevier, PA, USA 701-711 (2008).
47. O'Malley PG, Balden E, Tomkins G, Santoro J, Kroenke K, Jackson JL. Treatment of fibromyalgia with antidepressants: a meta-analysis. J. Gen. Intern. Med. 15(9), 659-666 (2000).
48. Arnold LM, Keck PE, Jr, Welge JA. Antidepressant treatment of fibromyalgia. A meta-analysis and review. Psychosomatics 41(2), 104-113 (2000).
49. Sayar K, Aksu G, Ak I, Tosun M. Venlafaxine treatment of fibromyalgia. Ann. Pharmacother. 37(11), 1561-1565 (2003).
50. Littlejohn GO, Guymer EK. Fibromyalgia syndrome: which antidepressant drug should we choose? Curr. Pharm. Des. 12(1), 3-9 (2006).
51. Arnold LM, Lu Y, Crofford LJ et al. A double-blind, multicenter trial comparing duloxetine with placebo in the treatment of fibromyalgia patients with or without major depressive disorder. Arthritis Rheum. 50(9), 2974-2984 (2004).
52. Arnold LM, Rosen A, Pritchett YL et al. A randomized, double-blind, placebocontrolled trial of duloxetine in the treatment of women with fibromyalgia with or without major depressive disorder. Pain 119(1-3), 5-15 (2005).
53. Gendreau RM, Thorn MD, Gendreau JF et al. Efficacy of milnacipran in patients with fibromyalgia. J. Rheumatol. 32(10), 1975-1985 (2005).
54. Clauw D, Mease P, Palmer R, Thacker K, Gendreau RM. Milnacipran for the treatment of fibromyalgia: a 15-week, randomized, double-blind, placebocontrolled trial. Program of Abstracts of the 9th Annual European League Against Rheumatism Congress. Paris, France (2008) (Abstract 366).
55. Arnold L, Goldenberg D, Clauw D, Palmer R, Mease P, Gendreau RM. One-year durability of response to milnacipran treatment in fibromyalgia. Program of Abstracts of the 9th Annual European League Against Rheumatism Congress. Paris, France (2008) (Abstract 359).
56. Hannonen P, Malminiemi K, Yli-Kerttula U, Isomeri R, Roponen P. A randomized, double-blind, placebo-controlled study of moclobemide and amitriptyline in the treatment of fibromyalgia in females without psychiatric disorder. Br. J. Rheumatol. 37(12), 1279-1286 (1998).
57. Anderberg UM, Marteinsdottir I, von Knorring L. Citalopram in patients with fibromyalgia - a randomized, double-blind, placebo-controlled study. Eur. J. Pain 4(1), 27-35 (2000).
58. Norregaard J, Volkmann H, Danneskiold-Samsoe B. A randomized controlled trial of citalopram in the treatment of fibromyalgia. Pain 61(3), 445-449 (1995).
59. Spath M, Stratz T, Neeck G et al. Efficacy and tolerability of intravenous tropisetron in the treatment of fibromyalgia. Scand. J. Rheumatol. 33(4), 267-270 (2004). (Pubitemid 39180172)
60. Farber L, Stratz TH, Bruckle W et al. Short-term treatment of primary fibromyalgia with the 5-HT3-receptor antagonist tropisetron. Results of a randomized, double-blind, placebocontrolled multicenter trial in 418 patients. Int. J. Clin. Pharmacol. Res. 21(1), 1-13 (2001).
61. Wood PB, Schweinhardt P, Jaeger E et al. Fibromyalgia patients show an abnormal dopamine response to pain. Eur. J. Neurosci. 25(12), 3576-3582 (2007).
62. Holman AJ, Myers RR. A randomized, double-blind, placebo-controlled trial of pramipexole, a dopamine agonist, in patients with fibromyalgia receiving concomitant medications. Arthritis Rheum. 52(8), 2495-2505 (2005).
63. DeMaria Jr S, Hassett AL, Sigal LH. N-methyl-d-aspartate receptor-mediated chronic pain: new approaches to fibromyalgia syndrome etiology and therapy. J. Musculoskel. Pain 15(2), 33-44 (2007).
64. Graven-Nielsen T, Aspegren Kendall S, Henriksson KG et al. Ketamine reduces muscle pain, temporal summation, and referred pain in fibromyalgia patients. Pain 85(3), 483-491 (2000).
65. Dworkin RH, O'Connor AB, Backonja M et al. Pharmacologic management of neuropathic pain: evidence-based recommendations. Pain 132(3), 237-251 (2007).
66. Dworkin RH, Corbin AE, Young JPJ et al. Pregabalin for the treatment of postherpetic neuralgia: a randomized, placebocontrolled trial. Neurology 60(8), 1274-1283 (2003).
67. Lesser H, Sharma U, LaMoreaux L, Poole RM. Pregabalin relieves symptoms of painful diabetic neuropathy: a randomized controlled trial. Neurology 63(11), 2104-2110 (2004). (Pubitemid 39636259)
68. Crofford LJ, Rowbotham MC, Mease PJ et al. Pregabalin for the treatment of fibromyalgia syndrome: results of a randomized, double-blind, placebocontrolled trial. Arthritis Rheum. 52(4), 1264-1273 (2005).
69. Mease PJ, Russell IJ, Arnold LM et al. A randomized, double-blind, placebocontrolled, Phase III trial of pregabalin in the treatment of patients with fibromyalgia. J. Rheumatol. 35(3), 502-514 (2008).
70. Crofford LJ, Mease PJ, Simpson SL et al. Fibromyalgia Relapse Evaluation and Efficacy for Durability of Meaningful Relief (FREEDOM): a 6-month, double-blind, placebo-controlled trial with pregabalin. Pain 136(3), 419-431 (2008).
71. Arnold LM, Crofford LJ, Martin SA, Young JP, Sharma U. The effect of anxiety and depression on improvements in pain in a randomized, controlled trial of pregabalin for treatment of fibromyalgia. Pain Med. 8(8), 633-638 (2007).
72. Arnold L, Leon T, Whalen E, Pauer L, Zeiher B, Barrett J. Treatment with pregabalin is associated with improvement in pain regardless of baseline symptoms of anxiety or depression. Program of Abstracts of the Annual European League Against Rheumatism Congress. Paris, France (2008) (Abstract 358).
73. Barrett J, Russell IJ, Pauer L, Whalen E, Leon T, Zeiher B. The effect of pregabalin treatment on changes in pain and sleep quality in fibromyalgia patients. Program of Abstracts of the Annual European League Against Rheumatism Congress. Paris, France (2008) (Abstract 362).
74. Arnold LM, Goldenberg DL, Stanford SB et al. Gabapentin in the treatment of fibromyalgia: a randomized, double-blind, placebo-controlled, multicenter trial. Arthritis Rheum. 56(4), 1336-1344 (2007).
75. Passard A, Attal N, Benadhira R et al. Effects of unilateral repetitive transcranial magnetic stimulation of the motor cortex on chronic widespread pain in fibromyalgia. Brain 130(Pt 10), 2661-2670 (2007).
76. Sampson SM, Rome JD, Rummans TA. Slow-frequency rTMS reduces fibromyalgia pain. Pain Med. 7(2), 115-118 (2006).
77. Thomas AW, Graham K, Prato FS et al. A randomized, double-blind, placebocontrolled clinical trial using a lowfrequency magnetic field in the treatment of musculoskeletal chronic pain. Pain Res. Manag. 12(4), 249-258 (2007).