Electrical stimulation for fracture healing: Current evidence

Journal of Orthopaedic Trauma

Volumn 24, Issue SUPPL. 1, 2010, Pages

  Goldstein, Christina ^a   Sprague, Sheila ^a,b   Petrisor, Bradley A ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

Bone growth stimulators; Electrical stimulation; Fracture healing; Nonunion

Indexed keywords

BONE GROWTH; DIRECT CURRENT; ELECTRIC FIELD; ELECTROMAGNETIC FIELD; ELECTROSTIMULATION; EVIDENCE BASED MEDICINE; FRACTURE; FRACTURE HEALING; FRACTURE NONUNION; GROWTH STIMULATION; HUMAN; MAGNETIC FIELD; NONHUMAN; OSSIFICATION; OSTEOTOMY; PRIORITY JOURNAL; SHORT SURVEY;

BONE AND BONES; ELECTRIC STIMULATION THERAPY; EVIDENCE-BASED MEDICINE; FRACTURE HEALING; FRACTURES, BONE; HUMANS;

EID: 77649124268     PISSN: 08905339     EISSN: None     Source Type: Journal    
DOI: 10.1097/BOT.0b013e3181cdde1b     Document Type: Short Survey

References (26)

1. Musculoskeletal Injuries Report: Incidence, Risk Factors and Prevention. Rosemont, IL: American Academy of Orthopaedic Surgeons; 2000.
2. Megas P. Classification of non-union. Injury. 2005;36(Suppl 4):S30-S37.
3. Sen MK, Miclau T. Autologous iliac crest bone graft: should it still be the gold standard for treating nonunions? Injury. 2007;38(Suppl 1):S75-S80.
4. Audige L, Griffin D, Bhandari M, et al. Path analysis of factors for delayed healing and nonunion in 416 operatively treated tibial shaft fractures. Clin Orthop Relat Res. 2005;438:221-232.
5. Bhandari M, Tornetta P III, Sprague S, et al. Predictors of reoperation following operative management of fractures of the tibial shaft. J Orthop Trauma. 2003;17:353-361.
6. Anglen J. The clinical use of bone stimulators. J South Orthop Assoc. 2003;12:46-54.
7. Karamitros AE, Kalentzos VN, Soucacos PN. Electric stimulation and hyperbaric oxygen therapy in the treatment of nonunions. Injury. 2006; 37(Suppl 1):S63-S73.
8. Nelson FR, Brighton CT, Ryaby J, et al. Use of physical forces in bone healing. J Am Acad Orthop Surg. 2003;11:344-354.
9. Matson M, Ricci R. Equity Research: Bone growth stimulation 2008 outlook. Wachovia Capital Markets, LLC, 2007.
10. Fukada E, Yasuda I. On the piezoelectric effect of bone. J Physical Soc Japan. 1957;12:1158-1169.
11. Anderson JC, Ericksson C. Electrical properties of wet collagen. Nature. 1968;218:166-168.
12. Cochran GVB, Pawluk RJ, Basett CAL. Electromechanical characteristics of bone under physiological moisture conditions. Clin Orthop. 1968;58: 249-270.
13. Aaron RK, Ciombor DM. Therapeutic effects of electromagnetic fields in the stimulation of connective tissue repair. J Cell Biochem. 1993;52: 42-46.
14. Friedenberg ZB, Roberts PG Jr, Didizian NH, et al. Stimulation of fracture healing by direct current in the rabbit fibula. J Bone Joint Surg Am. 1971; 53:1400-1408.
15. Fredericks DC, Nepola JV, Baker JT, et al. Effects of pulsed electromagnetic fields on bone healing in a rabbit tibial osteotomy model. J Orthop Trauma. 2000;14:93-100.
16. Inoue N, Ohnishi I, Chen D, et al. Effect of pulsed electromagnetic fields (PEMF) on late-phase osteotomy gap healing in a canine tibial model. J Orthop Res. 2002;20:1106-1114.
17. Aaron RK, Ciombor DM, Simon BJ. Treatment of nonunions with electric and electromagnetic fields. Clin Orthop. 2004;419:21-29.
18. Otter MW, McLeod KJ, Rubin CT. Effects of electromagnetic fields in experimental fracture repair. Clin Orthop Relat Res. 1998;(355 Suppl): S90-S104.
19. Pethica BA, Brownell J. The dose-response relationship in PEMF therapy of ununited fractures. Presented at: Transactions of the Eighth Annual Meeting of the Bioelectrical Repair and Growth Society; Washington, D.C., October 9-12, 1988.
20. Ryaby JT. Clinical effects of electromagnetic and electric fields on fracture healing. Clin Orthop Relat Res. 1998;(355 Suppl):S205-S215.
21. Akai M, Hayashi K. Effect of electrical stimulation on musculoskeletal systems: a meta-analysis of controlled clinical trials. Bioelectromagnetics. 2002;23:132-143.
22. Griffin XL, Warner F, Costa M. The role of electromagnetic stimulation in the management of established non-union of long-bone fractures: what is the evidence? Injury. 2008;39:419-429.
23. Walker NA, Denegar CR, Preische J. Low-intensity pulsed ultrasound and pulsed electromagnetic field in the treatment of tibial fractures: a systematic review. J Athl Train. 2007;42:530-535.
24. Mollon B, da SV, Busse JW, et al. Electrical stimulation for long-bone fracture-healing: a meta-analysis of randomized controlled trials. J Bone Joint Surg Am. 2008;90:2322-2330.
25. Betti E, Marchetti S, Cadossi R, et al. Effect of stimulation by low-frequency pulsed electromagnetic fields in subjects with fracture of the femoral neck. In: Bersani F, ed. Electricity and Magnetism in Biology and Medicine. New York, NY: Kluwer Academic/Plenum; 1999:853-855.
26. Busse JW, Morton E, Lacchetti C, et al. Current management of tibial shaft fractures: a survey of 450 Canadian orthopedic trauma surgeons. Acta Orthop. 2008;79:689-694.