Years of Disability-Adjusted Life Gained as a Result of Thrombolytic Therapy for Acute Ischemic Stroke

Stroke

Volumn 41, Issue 3, 2010, Pages 471-477

  Hong, Keun Sik ^a   Saver, Jeffrey L ^b  

^a Inje University   (South Korea)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Acute stroke trial; DALY; NINDS rt PA trial; Outcome; Thrombolysis

Indexed keywords

PLACEBO; TISSUE PLASMINOGEN ACTIVATOR;

ACUTE DISEASE; AGED; ARTICLE; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DISABILITY; FEMALE; FIBRINOLYTIC THERAPY; HAZARD RATIO; HUMAN; LIFE EXPECTANCY; MORTALITY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROGNOSIS; QUALITY OF LIFE; RANKIN SCALE; SCORING SYSTEM; STROKE;

AGED; AGED, 80 AND OVER; BRAIN ISCHEMIA; COHORT STUDIES; DISABLED PERSONS; FEMALE; HUMANS; MALE; MIDDLE AGED; NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE; QUALITY-ADJUSTED LIFE YEARS; STROKE; THROMBOLYTIC THERAPY; TISSUE PLASMINOGEN ACTIVATOR; TREATMENT OUTCOME; UNITED STATES;

EID: 77649121098     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/STROKEAHA.109.571083     Document Type: Article

References (14)

1. WHO. The global burden of disease: 2004 update. (http://www.who.int/ healthinfo/global-burden-disease/2004-report-update/en/index.html). Accessed 4/02/2009.
2. Ezzati M, Hoorn SV, Rodgers A, Lopez AD, Mathers CD, Murray CJ. Estimates of global and regional potential health gains from reducing multiple major risk factors. Lancet. 2003;362:271-280.
3. Moodie ML, Carter R, Mihalopoulos C, Thrift AG, Chambers BR, Donnan GA, Dewey HM. Trial application of a model of resource utilization, costs, and outcomes for stroke (MORUCOS) to assist priority setting in stroke. Stroke. 2004;35:1041-1046.
4. Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N Engl J Med. 1995;333:1581-1587.
5. Dachs RJ, Burton JH, Joslin J. A user's guide to the NINDS rt-PA stroke trial database. PLoS Med. 2008;5:e113.
6. Arias E. United States life tables 2004. Natl Vital Stat Rep. 2007;56:1-39.
7. Slot KB, Berge E, Dorman P, Lewis S, Dennis M, Sandercock P. Impact of functional status at six months on long term survival in patients with ischaemic stroke: prospective cohort studies. BMJ. 2008;336:376-379.
8. Eriksson M, Norrving B, Terent A, Stegmayr B. Functional outcome 3 months after stroke predicts long-term survival. Cerebrovasc Dis. 2008; 25:423-429.
9. Hong KS, Saver JL. Quantifying the value of stroke disability outcomes. WHO global burden of disease project disability weights for each level of the modified Rankin Scale. Stroke. 2009;40:3828-3833.
10. Murray CJ. Rethinking DALYs. In: Murray CJL, Lopez AD, eds. The Global Burden of Disease, Vol.1 of Global Burden of Disease and Injury Series. Cambridge, MA: Harvard University Press; 1996:1-98.
11. Saver JL. Number needed to treat estimates incorporating effects over the entire range of clinical outcomes: novel derivation method and application to thrombolytic therapy for acute stroke. Arch Neurol. 2004;61: 1066-1070.
12. Ali LK, Selco SL, Saver JL. The impact of secondary prevention therapies after stroke compared with a uniform metric: disability-adjusted life years (DALY) gained. 2007 International Stroke Conference (abstract). Stroke. 2007;38:e457.
13. Lloyd-Jones D, Adams R, Carnethon M, De Simone G, Ferguson TB, Flegal K, Ford E, Furie K, Go A, Greenlund K, Haase N, Hailpern S, Ho M, Howard V, Kissela B, Kittner S, Lackland D, Lisabeth L, Marelli A, McDermott M, Meigs J, Mozaffarian D, Nichol G, O'Donnell C, Roger V, Rosamond W, Sacco R, Sorlie P, Stafford R, Steinberger J, Thom T, Wasserthiel-Smoller S, Wong N, Wylie-Rosett J, Hong Y. Heart disease and stroke statistics-2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2009;119:480-486.
14. Fagan SC, Morgenstern LB, Petitta A, Ward RE, Tilley BC, Marler JR, Levine SR, Broderick JP, Kwiatkowski TG, Frankel M, Brott TG, Walker MD. Cost-effectiveness of tissue plasminogen activator for acute ische-mic stroke. NINDS rt-PA Stroke Study Group. Neurology. 1998;50: 883-890.