Transient bilateral abducens neuropathy with post-tetanic facilitation and acute hypokalemia associated with oxaliplatin: A case report

Journal of Medical Case Reports

Volumn 4, Issue , 2010, Pages

  Tan, Min Han ^a   Chay, Wen Yee ^a   Ng, Jia Hui ^a   Teh, Bin Tean ^a   Chew, Lita ^a  

^a DIVISION OF MEDICAL ONCOLOGY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CAPECITABINE; CETUXIMAB; CISPLATIN; DEXAMETHASONE; DOCETAXEL; EPIRUBICIN; FLUOROURACIL; IRINOTECAN; MAGNESIUM; ONDANSETRON; OXALIPLATIN; POTASSIUM; VOLTAGE GATED POTASSIUM CHANNEL;

ABDUCENS NERVE DISEASE; ADULT; ARTICLE; CASE REPORT; CLINICAL ASSESSMENT; CREATINE KINASE BLOOD LEVEL; DIPLOPIA; DRUG INFUSION; DYSARTHRIA; DYSESTHESIA; FEMALE; HUMAN; HYPOKALEMIA; LABORATORY DIAGNOSIS; LARYNGOPHARYNGODYSESTHESIA; MOTOR NEUROPATHY; MULTIPLE CYCLE TREATMENT; NERVE ENDING; NEUROTOXICITY; PERITONEUM METASTASIS; POST TETANIC POTENTIATION; PRIORITY JOURNAL; SIDE EFFECT; STOMACH CANCER; T WAVE INVERSION; TENDON REFLEX; TREATMENT OUTCOME; TREATMENT RESPONSE; WARMING;

EID: 77649115976     PISSN: 17521947     EISSN: 17521947     Source Type: Journal    
DOI: 10.1186/1752-1947-4-36     Document Type: Article

References (15)

1. Oxaliplatin-associated neuropathy: a review. RJ Cersosimo, Ann Pharmacother 2005 39 128 135 15590869
2. A review on oxaliplatin-induced peripheral nerve damage. AA Argyriou P Polychronopoulos G Iconomou E Chroni HP Kalofonos, Cancer Treat Rev 2008 34 368 377 10.1016/j.ctrv.2008.01.003 18281158
3. Acute Abnormalities of Sensory Nerve Function Associated With Oxaliplatin-Induced Neurotoxicity. SB Park D Goldstein CS Lin AV Krishnan ML Friedlander MC Kiernan, J Clin Oncol 2009 27 1243 1249 10.1200/JCO.2008.19.3425 19164207
4. A possible explanation for a neurotoxic effect of the anticancer agent oxaliplatin on neuronal voltage-gated sodium channels. F Grolleau L Gamelin M Boisdron-Celle B Lapied M Pelhate E Gamelin, J Neurophysiol 2001 85 2293 2297 11353042
5. Oxaliplatin-related neurotoxicity: interest of calcium-magnesium infusion and no impact on its efficacy. L Gamelin M Boisdron-Celle A Morel AL Poirier V Berger E Gamelin C Tournigand A de Gramont, J Clin Oncol 2008 26 1188 1189 10.1200/JCO.2007.15.3767 18309961
6. Acute oxaliplatin-induced peripheral nerve hyperexcitability. RH Wilson T Lehky RR Thomas MG Quinn MK Floeter JL Grem, J Clin Oncol 2002 20 1767 1774 10.1200/JCO.2002.07.056 11919233
7. The chemotherapeutic oxaliplatin alters voltage-gated Na(+) channel kinetics on rat sensory neurons. H Adelsberger S Quasthoff J Grosskreutz A Lepier F Eckel C Lersch, Eur J Pharmacol 2000 406 25 32 10.1016/S0014-2999(00) 00667-1 11011028
8. Oxaliplatin induces hyperexcitability at motor and autonomic neuromuscular junctions through effects on voltage-gated sodium channels. RG Webster KL Brain RH Wilson JL Grem A Vincent, Br J Pharmacol 2005 146 1027 1039 10.1038/sj.bjp.0706407 16231011
9. Oxaliplatin, an anticancer agent that affects both Na+ and K+ channels in frog peripheral myelinated axons. E Benoit S Brienza JM Dubois, Gen Physiol Biophys 2006 25 263 276 17197725
10. The effects of oxaliplatin, an anticancer drug, on potassium channels of the peripheral myelinated nerve fibres of the adult rat. A Kagiava A Tsingotjidou C Emmanouilides G Theophilidis, Neurotoxicology 2008 29 1100 1106 10.1016/j.neuro.2008.09.005 18845186
11. Acute bilateral abducens paralysis due to oxaliplatin. E Winquist M Vincent W Stadler, J Natl Cancer Inst 2003 95 488 489 12644545
12. Contribution of presynaptic calcium-activated potassium currents to transmitter release regulation in cultured Xenopus nerve-muscle synapses. JM Pattillo B Yazejian DA DiGregorio JL Vergara AD Grinnell SD Meriney, Neuroscience 2001 102 229 240 10.1016/S0306-4522(00)00453-X 11226687
13. A reversible coma after oxaliplatin administration suggests a pathogenetic role of electrolyte imbalance. M Basso A Cassano A Modoni D Spada N Trigila M Quirino G Schinzari C Barone, Eur J Clin Pharmacol 2008 64 739 741 10.1007/s00228-008-0474-x 18350285
14. Hypokalemic weakness in hyperaldosteronism: activity-dependent conduction block. AV Krishnan JG Colebatch MC Kiernan, Neurology 2005 65 1309 1312 10.1212/01.wnl.0000181162.35142.a9 16247066
15. Axonal hyperpolarization associated with acute hypokalemia: multiple excitability measurements as indicators of the membrane potential of human axons. S Kuwabara K Kanai JY Sung K Ogawara T Hattori D Burke H Bostock, Muscle Nerve 2002 26 283 287 10.1002/mus.10169 12210395