메뉴 건너뛰기




Volumn 21, Issue 3, 2010, Pages 301-310

Vanoxerine: Cellular mechanism of a new antiarrhythmic

Author keywords

Antiarrhythmic drug; Cardiac electrophysiology; GBR 12909; Patch clamp; Purkinje fiber action potential; Vanoxerine; Ventricular wedge

Indexed keywords

CALCIUM CHANNEL; POTASSIUM CHANNEL HERG; SODIUM CHANNEL; VANOXERINE; ANTIARRHYTHMIC AGENT; PIPERAZINE DERIVATIVE;

EID: 77649099565     PISSN: 10453873     EISSN: 15408167     Source Type: Journal    
DOI: 10.1111/j.1540-8167.2009.01623.x     Document Type: Article
Times cited : (36)

References (30)
  • 1
    • 33645211728 scopus 로고    scopus 로고
    • A perspective on antiarrhythmic drug therapy to treat atrial fibrillation: There remains an unmet need
    • Waldo AL : A perspective on antiarrhythmic drug therapy to treat atrial fibrillation: There remains an unmet need. Am Heart J 2006 151 : 771 778.
    • (2006) Am Heart J , vol.151 , pp. 771-778
    • Waldo, A.L.1
  • 2
    • 0037967287 scopus 로고    scopus 로고
    • Maintenance of sinus rhythm in patients with atrial fibrillation: An AFFIRM substudy of the first antiarrhythmic drug
    • AFFIRM First Antiarrhythmic Drug Substudy Investigators
    • AFFIRM First Antiarrhythmic Drug Substudy Investigators : Maintenance of sinus rhythm in patients with atrial fibrillation: An AFFIRM substudy of the first antiarrhythmic drug. J Am Coll Cardiol 2003 42 : 20 29.
    • (2003) J Am Coll Cardiol , vol.42 , pp. 20-29
  • 3
    • 0042347824 scopus 로고    scopus 로고
    • Drugs to promote sinus rhythm reversion and maintenance in atrial fibrillation-why amiodarone is better
    • Nattel S : Drugs to promote sinus rhythm reversion and maintenance in atrial fibrillation-why amiodarone is better. Cardiovasc Drugs Ther 2003 17 : 5 6.
    • (2003) Cardiovasc Drugs Ther , vol.17 , pp. 5-6
    • Nattel, S.1
  • 5
    • 0027049060 scopus 로고
    • Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter
    • Giros B, el Mestikawy S, Godinot N, Zheng K, Han H, Yang-Feng T, Caron MG : Cloning, pharmacological characterization, and chromosome assignment of the human dopamine transporter. Mol Pharmacol 1992 42 : 383 390.
    • (1992) Mol Pharmacol , vol.42 , pp. 383-390
    • Giros, B.1    El Mestikawy, S.2    Godinot, N.3    Zheng, K.4    Han, H.5    Yang-Feng, T.6    Caron, M.G.7
  • 6
    • 0033765786 scopus 로고    scopus 로고
    • Vanoxerine national institute on drug abuse
    • Preti A : Vanoxerine National Institute on Drug Abuse. Curr Opin Investig Drugs 2000 1 : 241 251.
    • (2000) Curr Opin Investig Drugs , vol.1 , pp. 241-251
    • Preti, A.1
  • 7
    • 0025351245 scopus 로고
    • + current. Differential sensitivity to block by class III antiarrhythmic agents
    • + current. Differential sensitivity to block by class III antiarrhythmic agents. J Gen Physiol 1990 96 : 195 215.
    • (1990) J Gen Physiol , vol.96 , pp. 195-215
    • Sanguinetti, M.C.1    Jurkiewicz, N.K.2
  • 9
    • 0027138820 scopus 로고
    • Nonlinear multiple-dose pharmacokinetics of the dopamine reuptake inhibitor vanoxerine
    • Ingwersen SH, Snel S, Mant TG, Edwards D : Nonlinear multiple-dose pharmacokinetics of the dopamine reuptake inhibitor vanoxerine. J Pharm Sci 1993 82 : 1164 1166.
    • (1993) J Pharm Sci , vol.82 , pp. 1164-1166
    • Ingwersen, S.H.1    Snel, S.2    Mant, T.G.3    Edwards, D.4
  • 10
    • 0027393884 scopus 로고
    • Food intake increases the relative oral bioavailability of vanoxerine
    • Ingwersen SH, Mant TG, Larsen JJ : Food intake increases the relative oral bioavailability of vanoxerine. Br J Clin Pharmacol 1993 35 : 308 310.
    • (1993) Br J Clin Pharmacol , vol.35 , pp. 308-310
    • Ingwersen, S.H.1    Mant, T.G.2    Larsen, J.J.3
  • 11
    • 0034588598 scopus 로고    scopus 로고
    • Drug-induced long QT syndrome: Is HERG the root of all evil?
    • Brown AM, Rampe D : Drug-induced long QT syndrome: Is HERG the root of all evil? Pharmaceutical News 2000 7 : 15 20.
    • (2000) Pharmaceutical News , vol.7 , pp. 15-20
    • Brown, A.M.1    Rampe, D.2
  • 19
    • 0032480753 scopus 로고    scopus 로고
    • Characteristics and distribution of M cells in arterially perfused canine left ventricular wedge preparations
    • Yan GX, Shimizu W, Antzelevitch C : Characteristics and distribution of M cells in arterially perfused canine left ventricular wedge preparations. Circulation 1998 98 : 1921 1927.
    • (1998) Circulation , vol.98 , pp. 1921-1927
    • Yan, G.X.1    Shimizu, W.2    Antzelevitch, C.3
  • 20
    • 33645807633 scopus 로고    scopus 로고
    • Short- and long-term amiodarone treatments regulate Cav3.2 low-voltage-activated T-type Ca2+ channel through distinct mechanisms
    • Yamashita N, Kaku T, Uchino T, Isomoto S, Yoshimatsu H, Ono K : Short- and long-term amiodarone treatments regulate Cav3.2 low-voltage-activated T-type Ca2+ channel through distinct mechanisms. Mol Pharmacol 2006 69 : 1684 1691.
    • (2006) Mol Pharmacol , vol.69 , pp. 1684-1691
    • Yamashita, N.1    Kaku, T.2    Uchino, T.3    Isomoto, S.4    Yoshimatsu, H.5    Ono, K.6
  • 21
    • 0034860484 scopus 로고    scopus 로고
    • Metabolism of vanoxerine, 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3- phenylpropyl)piperazine, by human cytochrome P450 enzymes
    • Cherstniakova SA, Bi D, Fuller DR, Mojsiak JZ, Collins JM, Cantilena LR : Metabolism of vanoxerine, 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3- phenylpropyl)piperazine, by human cytochrome P450 enzymes. Drug Metab Dispos 2001 29 : 1216 1220.
    • (2001) Drug Metab Dispos , vol.29 , pp. 1216-1220
    • Cherstniakova, S.A.1    Bi, D.2    Fuller, D.R.3    Mojsiak, J.Z.4    Collins, J.M.5    Cantilena, L.R.6
  • 23
    • 33646925208 scopus 로고    scopus 로고
    • Efficacy and tolerance of RSD1235 in the treatment of atrial fibrillation or atrial flutter: Results of a phase III, randomized, placebo-controlled, multicenter trial
    • (Abstract).
    • Pratt CM, Roy D, Juul-Moller S, Torp-Pedersen C, Toft E, Wyse DG, Nielsen T, Rasmussen SL : Efficacy and tolerance of RSD1235 in the treatment of atrial fibrillation or atrial flutter: Results of a phase III, randomized, placebo-controlled, multicenter trial. J Am Coll Cardiol 2006 47 : 10A (Abstract).
    • (2006) J Am Coll Cardiol , vol.47
    • Pratt, C.M.1    Roy, D.2    Juul-Moller, S.3    Torp-Pedersen, C.4    Toft, E.5    Wyse, D.G.6    Nielsen, T.7    Rasmussen, S.L.8
  • 24
    • 55549127942 scopus 로고    scopus 로고
    • Dronedarone: A new treatment for atrial fibrillation
    • Laughlin JC, Kowey PR : Dronedarone: A new treatment for atrial fibrillation. J Cardiovasc Electrophysiol 2008 19 : 1220 1226.
    • (2008) J Cardiovasc Electrophysiol , vol.19 , pp. 1220-1226
    • Laughlin, J.C.1    Kowey, P.R.2
  • 25
    • 0037438804 scopus 로고    scopus 로고
    • Amiodarone versus placebo and class Ic drugs for cardioversion of recent-onset atrial fibrillation: A meta-analysis
    • Chevalier P, Durand-Dubief A, Burri H, Cucherat M, Kirkorian G, Touboul P : Amiodarone versus placebo and class Ic drugs for cardioversion of recent-onset atrial fibrillation: A meta-analysis. J Am Coll Cardiol 2003 41 : 255 262.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 255-262
    • Chevalier, P.1    Durand-Dubief, A.2    Burri, H.3    Cucherat, M.4    Kirkorian, G.5    Touboul, P.6
  • 26
    • 34249773996 scopus 로고    scopus 로고
    • GBR12909 possesses anticonvulsant activity in Zebrafish and rodent models of generalized epilepsy but cardiac ion channel effects limit its clinical utility
    • Goldsmith P, Golder Z, Hunt J, Berghmans S, Jones D, Stables JP, Murphree L, Howden D, Newton PE, Richards FM : GBR12909 possesses anticonvulsant activity in Zebrafish and rodent models of generalized epilepsy but cardiac ion channel effects limit its clinical utility. Pharmacology 2007 79 : 250 258.
    • (2007) Pharmacology , vol.79 , pp. 250-258
    • Goldsmith, P.1    Golder, Z.2    Hunt, J.3    Berghmans, S.4    Jones, D.5    Stables, J.P.6    Murphree, L.7    Howden, D.8    Newton, P.E.9    Richards, F.M.10
  • 27
    • 0029002142 scopus 로고
    • Survival with oral d-sotalol in patients with left ventricular dysfunction after myocardial infarction: Rationale, design, and methods (the SWORD trial)
    • Waldo AL, Camm AJ, deRuyter H, Freidman PL, MacNeil DJ, Pitt B, Pratt CM, Rodda BE, Schwartz PJ : Survival with oral d-sotalol in patients with left ventricular dysfunction after myocardial infarction: Rationale, design, and methods (the SWORD trial). Am J Cardiol 1995 75 : 1023 1027.
    • (1995) Am J Cardiol , vol.75 , pp. 1023-1027
    • Waldo, A.L.1    Camm, A.J.2    Deruyter, H.3    Freidman, P.L.4    MacNeil, D.J.5    Pitt, B.6    Pratt, C.M.7    Rodda, B.E.8    Schwartz, P.J.9
  • 28
    • 0030949618 scopus 로고    scopus 로고
    • Very early onset of acute amiodarone pulmonary toxicity presenting with hemoptysis
    • Goldstein I, Topilsky M, Segev D, Isakov A, Heller I : Very early onset of acute amiodarone pulmonary toxicity presenting with hemoptysis. Chest 1997 111 : 1446 1447.
    • (1997) Chest , vol.111 , pp. 1446-1447
    • Goldstein, I.1    Topilsky, M.2    Segev, D.3    Isakov, A.4    Heller, I.5
  • 29
    • 0032747161 scopus 로고    scopus 로고
    • Clinical organ toxicity of antiarrhythmic compounds: Ocular and pulmonary manifestations
    • Pollak PT : Clinical organ toxicity of antiarrhythmic compounds: Ocular and pulmonary manifestations. Am J Cardiol 1999 84 : 37R 45R.
    • (1999) Am J Cardiol , vol.84
    • Pollak, P.T.1
  • 30
    • 77649143446 scopus 로고    scopus 로고
    • Orally administered vanoxerine, a cardiac multichcannel blocker, terminates atrial flutter and prevents its reinducibility in the canine sterile pericarditis model
    • Cakulev I, Kyungmoo R, Celeen K, Lacerda AE, Brown AM, Waldo AL : Orally administered vanoxerine, a cardiac multichcannel blocker, terminates atrial flutter and prevents its reinducibility in the canine sterile pericarditis model. J Am Coll Cardiol 2007 49 : 38A.
    • (2007) J Am Coll Cardiol , vol.49
    • Cakulev, I.1    Kyungmoo, R.2    Celeen, K.3    Lacerda, A.E.4    Brown, A.M.5    Waldo, A.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.