Aqueous extract and methanol fractions of the leaves of Brillantaisia nitens Lindau. reverses phenylhydrazine - Induced anaemia in rats

Journal of Medicinal Plants Research

Volumn 4, Issue 3, 2010, Pages 271-277

  Akah, P A ^a   Okolo, C E ^a   Okoye, T C ^a   Offiah, N V ^b  

^a UNIVERSITY OF NIGERIA   (Nigeria)

^b UNIVERSITY OF THE WEST INDIES   (Trinidad and Tobago)

Author keywords

Blood parameters; Brillantaisia nitens; Hematinic effects; Phenylhydrazine; Rats

Indexed keywords

ALKALOID; ALPHA TOCOPHEROL; ANTIANEMIC AGENT; ASCORBIC ACID; BRILLANTAISIA NITENS EXTRACT; CARBOHYDRATE; CHLOROFORM; CYANOCOBALAMIN; FLAVONOID; FOLIC ACID; GLYCOSIDE; HEMOGLOBIN; HEXANE; IRON; METHANOL; PHENYLHYDRAZINE; PLANT EXTRACT; PLANT RESIN; PYRIDOXINE; SAPONIN; TERPENOID; UNCLASSIFIED DRUG;

ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; AQUEOUS SOLUTION; ARTICLE; BRILLANTAISIA NITENS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG EFFECT; DRUG SAFETY; DRUG SCREENING; DRUG STRUCTURE; ERYTHROCYTE COUNT; FEMALE; HEMATOCRIT; HEMOGLOBIN DETERMINATION; LD 50; LEUKOCYTE COUNT; MALE; MEDICINAL PLANT; NONHUMAN; PLANT LEAF; RAT;

BRILLANTAISIA NITENS; RATTUS;

EID: 77649088907     PISSN: 19960875     EISSN: 19960875     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Adjanohoun JE, Aboubakar N, Dramane NN (1996). Contribution to ethnobotanical and floristic studies in Cameroon. Center National de producastiondes manuels scolaire, Benin Vol. 19.
2. Adusi-Poku Y, Sittie A, Mensah MLK, Sarpong K, Fleischer TC, Ankrah TC, Nsiah D (2008). Effectiveness and Safety Assessment of Mist Tonica, a Herbal Haematinic. Afr. J. Tradit. Complimen. Altern. Med. 5(2): 115-119.
3. Agbor GA, Oben JE, Ngogang JY (2005). Haematinic activity of Hibiscus cannabinus . Afr. J. Biotechnol. 4(8): 833-837.
4. Akah PA, Okolo CE, Ezike AC (2009). The haematinic activity of the methanol leaf extract of Brillantasia nitens Lindau (Acanthaceae) in rats. Afr. J. Biotechnol. 8 (10): 2389-2393.
5. Berger J (2007). Phenylhydrazine haematotoxicity. J. Appl. Biomed. 5: 125-130.
6. Chanarin T, MacGibbon BM, O'sullivan WJ, Mollin D.J. (2004). Folic acid deficiency in pregnancy. Lancet 69: 634-635.
7. Criswell K, Sulhanen A, Hochbaum AF, Bleavens M (2002). Effect of PHZ or phlebotomy on peripheral blood, bone marrow and erythropoietin in Wistar rats J. Appl Toxicol. 20: 25-29.
8. Dacie, JV, Lewis SM (1991). Practical Haematology 7th Ed. Churchill Livingstone (London) pp. 659 -661.
9. Diallo A, Gbeassor M, Ahoeta V, Kwashie E (2008) Effect of Tectona grandis on phenylhydrazine induced anaemia in rats. Fitoterapia 79: 332-336.
10. Dimo T, Mtopi OS, Nguelefack TB, Kamtchoung P (2007) Vasorelarant effect of Brillantaisia nitens Iindau (Acanthacee) extracts on isolated rat vascular smooth muscle. J. Ethnopharmacol 111(1):104-109.
11. 12: A report of a joint FAO/WHO expert on consultation. Nutr. Series 23(8): 82-84.
12. Frenchman R, Johnston FA (1994). Relation of menstrual losses with iron requirement. J. Am. Diet. Assoc. 25: 217.
13. nd ed. London: Chapman and Hall; pp. 55-56.
14. Holden J, Acomb C (2007). Anaemia. In: Clinical Pharmacy and Therapeutics. Eds. Walker R and Whittlesea C. Churchil Livingstone, New York. Pp: 699-701.
15. Lorke D (1983). A new approach to practical acute toxicity testing. Arch. Toxicol. 54: 272-289.
16. Matheus ME, Berrondo LF, Vieitas EC (2005). Evaluation of the antinociceptive properties from Brillantaisis Palisolti Iindau stems extract. J. Ethnopharmacol 102(3): 377 -381.
17. Mtopi OS, Dimo T, Nguelefack TB, Dzeufiet DD, Rakotonirina SV, Kamtchouing P (2007). Effect of Brillantaisia nitens Iindau (Acanthaceae) methylene Chloride/ methanol leaf extraction on rat arterial blood pressure and heart rate. Pharmacol. Online 1: 495 - 510.
18. O' Riordan DK, Sharp P, Sykes RM, Epstein O, Debnam ES (1995). Response to PHZ-induced haemolytic anaemia. Eur. Clin. Invest. 25: 722.
19. Okochi YI, Okpuzor J, Alli LA (2003) Comparison of an African herbal formula with commercially available hematinics. Afr. J. Biotechnol. 2(8): 237 - 240.
20. Olokodana FA (2005). Analysis of fruit drinks and fruit juices. Institute of Public Analysts of Nigeria (IPAN) Bulletin, 6 (24): 9-14.
21. Onwuka GI (2005). Food Analysis and Instrumentation: Theory and Practical. Naphthali Prints Lagos Nigeria. pp. 77-79
22. Pearson D (1976). The chemical Analysis of foods. Churchill livingstone. New York. 7th edn. p. 54
23. th Edn. pp 350-353.
24. 12 in nutrition. In Clinical Nutrition edited by N. Joliffe. New York Herper and Row. p. 635.
25. th ed. London: Bailliere Tindall; pp. 315-679.
26. Yeshoda KM (1942). Phenylhydrazine anaemia in rats. Curr. Sci. 11: 360-363