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Volumn 1321, Issue , 2010, Pages 88-95

Erythropoietin-induced neuroprotection requires cystine glutamate exchanger activity

Author keywords

Cystine glutamate exchanger; Erythropoietin; Neuroprotection; xCT

Indexed keywords

CYSTINE; ERYTHROPOIETIN; GLUTAMIC ACID; GLUTATHIONE; KAINIC ACID; SMALL INTERFERING RNA;

EID: 77549083364     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2010.01.040     Document Type: Article
Times cited : (25)

References (34)
  • 1
    • 0032529347 scopus 로고    scopus 로고
    • Maturation-dependent vulnerability of oligodendrocytes to oxidative stress-induced death caused by glutathione depletion
    • Back S.A., et al. Maturation-dependent vulnerability of oligodendrocytes to oxidative stress-induced death caused by glutathione depletion. J. Neurosci. 18 (1998) 6241-6253
    • (1998) J. Neurosci. , vol.18 , pp. 6241-6253
    • Back, S.A.1
  • 2
    • 0036712960 scopus 로고    scopus 로고
    • Erythropoietin and the brain: from neurodevelopment to neuroprotection
    • Buemi M., et al. Erythropoietin and the brain: from neurodevelopment to neuroprotection. Clin. Sci. (Lond). 103 (2002) 275-282
    • (2002) Clin. Sci. (Lond). , vol.103 , pp. 275-282
    • Buemi, M.1
  • 3
    • 0034637297 scopus 로고    scopus 로고
    • Erythropoietin protects against brain ischemic injury by inhibition of nitric oxide formation
    • Calapai G., et al. Erythropoietin protects against brain ischemic injury by inhibition of nitric oxide formation. Eur. J. Pharmacol. 401 (2000) 349-356
    • (2000) Eur. J. Pharmacol. , vol.401 , pp. 349-356
    • Calapai, G.1
  • 4
    • 0037369477 scopus 로고    scopus 로고
    • Erythropoietin prevents early and late neuronal demise through modulation of Akt1 and induction of caspase 1, 3, and 8
    • Chong Z.Z., et al. Erythropoietin prevents early and late neuronal demise through modulation of Akt1 and induction of caspase 1, 3, and 8. J. Neurosci. Res. 71 (2003) 659-669
    • (2003) J. Neurosci. Res. , vol.71 , pp. 659-669
    • Chong, Z.Z.1
  • 5
    • 34547797469 scopus 로고    scopus 로고
    • Vascular injury during elevated glucose can be mitigated by erythropoietin and Wnt signaling
    • Chong Z.Z., et al. Vascular injury during elevated glucose can be mitigated by erythropoietin and Wnt signaling. Curr. Neurovasc. Res. 4 (2007) 194-204
    • (2007) Curr. Neurovasc. Res. , vol.4 , pp. 194-204
    • Chong, Z.Z.1
  • 6
    • 23444449591 scopus 로고    scopus 로고
    • Inhibition of cystine uptake disrupts the growth of primary brain tumors
    • Chung W.J., et al. Inhibition of cystine uptake disrupts the growth of primary brain tumors. J. Neurosci. 25 (2005) 7101-7110
    • (2005) J. Neurosci. , vol.25 , pp. 7101-7110
    • Chung, W.J.1
  • 7
    • 34247853270 scopus 로고    scopus 로고
    • Essential role of endothelial nitric oxide synthase in vascular effects of erythropoietin
    • d'Uscio L.V., et al. Essential role of endothelial nitric oxide synthase in vascular effects of erythropoietin. Hypertension 49 (2007) 1142-1148
    • (2007) Hypertension , vol.49 , pp. 1142-1148
    • d'Uscio, L.V.1
  • 8
    • 0035833541 scopus 로고    scopus 로고
    • Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades
    • Digicaylioglu M., and Lipton S.A. Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades. Nature 412 (2001) 641-647
    • (2001) Nature , vol.412 , pp. 641-647
    • Digicaylioglu, M.1    Lipton, S.A.2
  • 9
    • 1642484480 scopus 로고    scopus 로고
    • Adenoviral gene transfer of erythropoietin confers cytoprotection to isolated pancreatic islets
    • Fenjves E.S., et al. Adenoviral gene transfer of erythropoietin confers cytoprotection to isolated pancreatic islets. Transplantation 77 (2004) 13-18
    • (2004) Transplantation , vol.77 , pp. 13-18
    • Fenjves, E.S.1
  • 10
    • 0037087120 scopus 로고    scopus 로고
    • Erythropoietin restores glutathione peroxidase activity in 1-methyl-4-phenyl-1, 2, 5, 6-tetrahydropyridine-induced neurotoxicity in C57BL mice and stimulates murine astroglial glutathione peroxidase production in vitro
    • Genc S., et al. Erythropoietin restores glutathione peroxidase activity in 1-methyl-4-phenyl-1, 2, 5, 6-tetrahydropyridine-induced neurotoxicity in C57BL mice and stimulates murine astroglial glutathione peroxidase production in vitro. Neurosci. Lett. 321 (2002) 73-76
    • (2002) Neurosci. Lett. , vol.321 , pp. 73-76
    • Genc, S.1
  • 11
    • 4344603795 scopus 로고    scopus 로고
    • Erythropoietin as an antiapoptotic, tissue-protective cytokine
    • Ghezzi P., and Brines M. Erythropoietin as an antiapoptotic, tissue-protective cytokine. Cell Death Differ. 11 Suppl 1 (2004) S37-S44
    • (2004) Cell Death Differ. , vol.11 , Issue.SUPPL. 1
    • Ghezzi, P.1    Brines, M.2
  • 12
    • 35348846589 scopus 로고    scopus 로고
    • Erythropoietin protects the intestine against ischemia/reperfusion injury in rats
    • Guneli E., et al. Erythropoietin protects the intestine against ischemia/reperfusion injury in rats. Mol. Med. 13 (2007) 509-517
    • (2007) Mol. Med. , vol.13 , pp. 509-517
    • Guneli, E.1
  • 13
    • 33646846617 scopus 로고    scopus 로고
    • The brain erythropoietin system and its potential for therapeutic exploitation in brain disease
    • Hasselblatt M., et al. The brain erythropoietin system and its potential for therapeutic exploitation in brain disease. J. Neurosurg. Anesthesiol. 18 (2006) 132-138
    • (2006) J. Neurosurg. Anesthesiol. , vol.18 , pp. 132-138
    • Hasselblatt, M.1
  • 14
    • 36348966705 scopus 로고    scopus 로고
    • Cellular protection by erythropoietin: new therapeutic implications?
    • Joyeux-Faure M. Cellular protection by erythropoietin: new therapeutic implications?. J. Pharmacol. Exp. Ther. 323 (2007) 759-762
    • (2007) J. Pharmacol. Exp. Ther. , vol.323 , pp. 759-762
    • Joyeux-Faure, M.1
  • 15
    • 35348964674 scopus 로고    scopus 로고
    • Antioxidative effects of erythropoietin
    • Katavetin P., et al. Antioxidative effects of erythropoietin. Kidney Int. Suppl. (2007) S10-S15
    • (2007) Kidney Int. Suppl.
    • Katavetin, P.1
  • 16
    • 0029047897 scopus 로고
    • Erythropoietin and the anaemia of chronic disease
    • Krantz S.B. Erythropoietin and the anaemia of chronic disease. Nephrol. Dial. Transplant. 10 Suppl 2 (1995) 10-17
    • (1995) Nephrol. Dial. Transplant. , vol.10 , Issue.SUPPL. 2 , pp. 10-17
    • Krantz, S.B.1
  • 17
    • 43749105309 scopus 로고    scopus 로고
    • Do non-hemopoietic effects of erythropoietin play a beneficial role in heart failure?
    • Latini R., et al. Do non-hemopoietic effects of erythropoietin play a beneficial role in heart failure?. Heart Fail. Rev. 13 (2008) 415-423
    • (2008) Heart Fail. Rev. , vol.13 , pp. 415-423
    • Latini, R.1
  • 18
    • 20444430402 scopus 로고    scopus 로고
    • Neuroprotection by hypoxic preconditioning involves oxidative stress-mediated expression of hypoxia-inducible factor and erythropoietin
    • Liu J., et al. Neuroprotection by hypoxic preconditioning involves oxidative stress-mediated expression of hypoxia-inducible factor and erythropoietin. Stroke 36 (2005) 1264-1269
    • (2005) Stroke , vol.36 , pp. 1264-1269
    • Liu, J.1
  • 19
    • 33947711717 scopus 로고    scopus 로고
    • Erythropoietin/erythropoietin receptor system is involved in angiogenesis in human neuroblastoma
    • Ribatti D., et al. Erythropoietin/erythropoietin receptor system is involved in angiogenesis in human neuroblastoma. Histopathology 50 (2007) 636-641
    • (2007) Histopathology , vol.50 , pp. 636-641
    • Ribatti, D.1
  • 20
    • 4444382950 scopus 로고    scopus 로고
    • Excitatory amino acid induced oligodendrocyte cell death in vitro: receptor-dependent and -independent mechanisms
    • Rosin C., et al. Excitatory amino acid induced oligodendrocyte cell death in vitro: receptor-dependent and -independent mechanisms. J. Neurochem. 90 (2004) 1173-1185
    • (2004) J. Neurochem. , vol.90 , pp. 1173-1185
    • Rosin, C.1
  • 21
    • 0036896201 scopus 로고    scopus 로고
    • Erythropoietin is a paracrine mediator of ischemic tolerance in the brain: evidence from an in vitro model
    • Ruscher K., et al. Erythropoietin is a paracrine mediator of ischemic tolerance in the brain: evidence from an in vitro model. J. Neurosci. 22 (2002) 10291-10301
    • (2002) J. Neurosci. , vol.22 , pp. 10291-10301
    • Ruscher, K.1
  • 22
    • 34548161623 scopus 로고    scopus 로고
    • Expression of erythropoietin and its receptor in neuroblastomas
    • Sartelet H., et al. Expression of erythropoietin and its receptor in neuroblastomas. Cancer 110 (2007) 1096-1106
    • (2007) Cancer , vol.110 , pp. 1096-1106
    • Sartelet, H.1
  • 23
    • 0034527749 scopus 로고    scopus 로고
    • Molecular cloning and expression of human xCT, the light chain of amino acid transport system Xc
    • Sato H., et al. Molecular cloning and expression of human xCT, the light chain of amino acid transport system Xc. Antioxid. Redox Signal. 2 (2000) 665-671
    • (2000) Antioxid. Redox Signal. , vol.2 , pp. 665-671
    • Sato, H.1
  • 24
    • 0037107162 scopus 로고    scopus 로고
    • Distribution of cystine/glutamate exchange transporter, system X(c)-, in the mouse brain
    • Sato H., et al. Distribution of cystine/glutamate exchange transporter, system X(c)-, in the mouse brain. J. Neurosci. 22 (2002) 8028-8033
    • (2002) J. Neurosci. , vol.22 , pp. 8028-8033
    • Sato, H.1
  • 25
    • 0031970848 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) activates Raf-1, mitogen-activated protein (MAP) kinases, and S6 kinase (p90rsk) in cultured rat cardiac myocytes
    • Seko Y., et al. Vascular endothelial growth factor (VEGF) activates Raf-1, mitogen-activated protein (MAP) kinases, and S6 kinase (p90rsk) in cultured rat cardiac myocytes. J. Cell. Physiol. 175 (1998) 239-246
    • (1998) J. Cell. Physiol. , vol.175 , pp. 239-246
    • Seko, Y.1
  • 26
    • 0037996661 scopus 로고    scopus 로고
    • Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress
    • Shih A.Y., et al. Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress. J. Neurosci. 23 (2003) 3394-3406
    • (2003) J. Neurosci. , vol.23 , pp. 3394-3406
    • Shih, A.Y.1
  • 27
    • 33749831751 scopus 로고    scopus 로고
    • Cystine/glutamate exchange modulates glutathione supply for neuroprotection from oxidative stress and cell proliferation
    • Shih A.Y., et al. Cystine/glutamate exchange modulates glutathione supply for neuroprotection from oxidative stress and cell proliferation. J. Neurosci. 26 (2006) 10514-10523
    • (2006) J. Neurosci. , vol.26 , pp. 10514-10523
    • Shih, A.Y.1
  • 28
    • 15244341057 scopus 로고    scopus 로고
    • Erythropoietin after focal cerebral ischemia activates the Janus kinase-signal transducer and activator of transcription signaling pathway and improves brain injury in postnatal day 7 rats
    • Sola A., et al. Erythropoietin after focal cerebral ischemia activates the Janus kinase-signal transducer and activator of transcription signaling pathway and improves brain injury in postnatal day 7 rats. Pediatr. Res. 57 (2005) 481-487
    • (2005) Pediatr. Res. , vol.57 , pp. 481-487
    • Sola, A.1
  • 29
    • 33846359319 scopus 로고    scopus 로고
    • Erythropoietin prevents oxidative stress and lipid peroxidation process in human umbilical vein endothelial cells induced by tumor necrosis factor alpha
    • Szczepanski M., et al. Erythropoietin prevents oxidative stress and lipid peroxidation process in human umbilical vein endothelial cells induced by tumor necrosis factor alpha. Pol. Merkur. Lekarski. 21 (2006) 534-539
    • (2006) Pol. Merkur. Lekarski. , vol.21 , pp. 534-539
    • Szczepanski, M.1
  • 30
    • 0031739636 scopus 로고    scopus 로고
    • Thrombopoietin serum concentration in patients with reactive and myeloproliferative thrombocytosis
    • Uppenkamp M., et al. Thrombopoietin serum concentration in patients with reactive and myeloproliferative thrombocytosis. Ann. Hematol. 77 (1998) 217-223
    • (1998) Ann. Hematol. , vol.77 , pp. 217-223
    • Uppenkamp, M.1
  • 31
    • 0026637988 scopus 로고
    • The 4F2 antigen heavy chain induces uptake of neutral and dibasic amino acids in Xenopus oocytes
    • Wells R.G., et al. The 4F2 antigen heavy chain induces uptake of neutral and dibasic amino acids in Xenopus oocytes. J. Biol. Chem. 267 (1992) 15285-15288
    • (1992) J. Biol. Chem. , vol.267 , pp. 15285-15288
    • Wells, R.G.1
  • 32
    • 34250866187 scopus 로고    scopus 로고
    • Erythropoietin prevents PC12 cells from 1-methyl-4-phenylpyridinium ion-induced apoptosis via the Akt/GSK-3beta/caspase-3 mediated signaling pathway
    • Wu Y., et al. Erythropoietin prevents PC12 cells from 1-methyl-4-phenylpyridinium ion-induced apoptosis via the Akt/GSK-3beta/caspase-3 mediated signaling pathway. Apoptosis 12 (2007) 1365-1375
    • (2007) Apoptosis , vol.12 , pp. 1365-1375
    • Wu, Y.1
  • 33
    • 4344611970 scopus 로고    scopus 로고
    • Effect of erythropoietin on nitric oxide production in the rat hippocampus using in vivo brain microdialysis
    • Yamamoto M., et al. Effect of erythropoietin on nitric oxide production in the rat hippocampus using in vivo brain microdialysis. Neuroscience 128 (2004) 163-168
    • (2004) Neuroscience , vol.128 , pp. 163-168
    • Yamamoto, M.1
  • 34
    • 0036333152 scopus 로고    scopus 로고
    • Erythropoietin receptor signalling is required for normal brain development
    • Yu X., et al. Erythropoietin receptor signalling is required for normal brain development. Development 129 (2002) 505-516
    • (2002) Development , vol.129 , pp. 505-516
    • Yu, X.1


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