Reduction of amiodarone pulmonary toxicity in patients treated with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers

Therapeutic Advances in Respiratory Disease

Volumn 3, Issue 6, 2009, Pages 289-294

  Kosseifi, Semaan G ^a   Halawa, Ahmad ^b   Bailey, Beth ^b   Micklewright, Melinda ^a,c   Roy, Thomas M ^a,c   Byrd, Ryland P ^a,c  

^a EAST TENNESSEE STATE UNIVERSITY   (United States)

^b East Tennessee State University   (United States)

^c James H Quillen VA Medical Center   (United States)

Author keywords

amiodarone; angiotensin receptor blockers; angiotensin converting enzyme inhibitors; pulmonary toxicity

Indexed keywords

AMIODARONE; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANTIARRHYTHMIC AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR;

ADULT; AGED; APOPTOSIS; ARTICLE; CHEMICALLY INDUCED DISORDER; CYTOLOGY; DRUG EFFECT; FEMALE; HUMAN; LUNG; LUNG DISEASE; MALE; MIDDLE AGED; PATHOPHYSIOLOGY; PUBLIC HOSPITAL; RETROSPECTIVE STUDY; UNITED STATES;

ADULT; AGED; AGED, 80 AND OVER; AMIODARONE; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANTI-ARRHYTHMIA AGENTS; APOPTOSIS; FEMALE; HOSPITALS, VETERANS; HUMANS; LUNG; LUNG DISEASES; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; UNITED STATES;

EID: 77449146485     PISSN: 17534658     EISSN: None     Source Type: Journal    
DOI: 10.1177/1753465809348015     Document Type: Article

References (12)

1. Bargout, R., Jankov, A., Dincer, E., Wang, R., Komodromos, T., Ibarra-Sunga, O. et al. (2000) Amiodarone induces apoptosis of human and rat alveolar epithelial cells in vitro. Am J Physiol Lung Cell Mol Physiol 278: L1039-L1044.
2. Epler, G.R. (2004) Drug-induced bronchiolitis obliterans organizing pneumonia. Clin Chest Med 25: 89-94.
3. Iskandar, S.B., Kasasbeh, E.S., Mechleb, B.K., Garcia, I., Jackson, A., Fahrig, S. et al. (2006) Alveolar hemorrhage: an underdiagnosed complication of treatment with glycoprotein IIb/IIIa inhibitors. J Inter v Cardiol 19: 356-363.
4. Lamont, J., Verbeken, E., Verschakelen, J. and Demedts, M. (1998) Bronchiolitis obliterans organising pneumonia. A report of 11 cases and a review of the literature. Acta Clin Belg 53: 328-336.
5. Li, X., Zhang, H., Soledad-Conrad, V., Zhuang, J. and Uhal, B.D. (2003) Bleomycin-induced apoptosis of alveolar epithelial cells requires angiotensin synthesis de novo. Am J Physiol 284: L501-507.
6. Martin, W.J. and Rosenow III, E.C. (1988) Amiodarone pulmonary toxicity. Recognition and pathogenesis (Part I). Chest 93: 1067-1075.
7. Ott, M.C., Khoor, A., Leventhal, J.P., Paterick, T.E. and Burger, C.D. (2003) Pulmonary toxicity in patients receiving low-dose amiodarone. Chest 123: 646-651.
8. Sunderji, R., Kanji, Z. and Gin, K. (2000) Pulmonary effects of low dose amiodarone: a review of the risks and recommendations for surveillance. Can J Cardiol 16: 1435-1440.
9. Uhal, B.D., Wang, R., Laukka, J., Zhuang, J., Soledad-Conrad, V. and Filippatos, G. (2003) Inhibition of amiodarone-induced lung fibrosis but not alveolitis by angiotensin system antagonists. Pharmacol Toxicol 92: 81-87.
10. Uhal, B.D., Zhang, H., Abdul-Hafez, A., Shu, R. and Li, X. (2007) Amiodarone induces angiotensinogen gene expression in lung alveolar epithelial cells through activation protein-1. Basic Clin Pharmacol Toxicol 100: 59-66.
11. Wilson, B.D. and Lippmann, M.L. (1990) Pulmonary accumulation of amiodarone and N-desethylamiodarone. Relationship to the development of pulmonary toxicity. Am Rev Respir Dis 141: 1553-1558.
12. Zitnik, R.J. (1996) Drug-induced lung disease: Antiarrhythmic agents. J Respir Dis 17: 254.