A high-throughput assay for DNA topoisomerases and other enzymes, based on DNA triplex formation.

Methods in molecular biology (Clifton, N.J.)

Volumn 613, Issue , 2010, Pages 257-266

  Burrell, Matthew R ^a   Burton, Nicolas P ^a   Maxwell, Anthony ^a  

^a JOHN INNES CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); ENZYME INHIBITOR; OLIGODEOXYRIBONUCLEOTIDE; TRIPLEX DNA;

ANIMAL; ARTICLE; CATTLE; CHEMISTRY; DNA SUPERCOILING; DRUG ANTAGONISM; ENZYME ASSAY; ENZYMOLOGY; ESCHERICHIA COLI; GENETICS; HIGH THROUGHPUT SCREENING; HUMAN; IC 50; METABOLISM; METHODOLOGY; NUCLEOTIDE SEQUENCE;

ANIMALS; BASE SEQUENCE; CATTLE; DNA; DNA GYRASE; DNA TOPOISOMERASES, TYPE I; DNA, SUPERHELICAL; ENZYME ASSAYS; ENZYME INHIBITORS; ESCHERICHIA COLI; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; INHIBITORY CONCENTRATION 50; OLIGODEOXYRIBONUCLEOTIDES;

MLCS; MLOWN;

EID: 77449140073     PISSN: None     EISSN: 19406029     Source Type: Journal    
DOI: 10.1007/978-1-60327-418-0_16     Document Type: Article

References (0)