Calcium regulation of non-kinase and kinase activities of recombinant myosin light-chain kinase and its mutants

IUBMB Life

Volumn 61, Issue 11, 2009, Pages 1092-1098

  Xie, Ce ^a,b   Zhang, Yue ^b   Wang, Hong Hui ^a   Matsumoto, Atsushi ^a   Nakamura, Akio ^a,c   Ishikawa, Ryoki ^a,c   Yoshiyama, Shinji ^a,c   Hayakawa, Kohichi ^a   Kohama, Kazuhiro ^a,c   Gao, Ying ^b  

^a GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b DALIAN MEDICAL UNIVERSITY   (China)

^c MARSHALL UNIVERSITY   (United States)

Author keywords

Calcium regulation; Calmodulin; Kinase activity; Myosin atpase activity; Myosin light chain kinase; Myosin motor activity; Non kinase activity; Recombinant protein; Smooth muscle

Indexed keywords

ACTIN; ADENOSINE TRIPHOSPHATASE; CALCIUM; CALCIUM ION; CALMODULIN; MYOSIN; MYOSIN LIGHT CHAIN KINASE; PHOSPHOTRANSFERASE; CALCIUM BINDING PROTEIN; MYOSIN LIGHT CHAIN; RECOMBINANT PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ESCHERICHIA COLI; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PURIFICATION; BINDING SITE; DRUG EFFECT; ENZYME ACTIVE SITE; ENZYMOLOGY; GENETICS; METABOLISM; MUTATION; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

ESCHERICHIA COLI;

ACTINS; BINDING SITES; CALCIUM; CALCIUM-BINDING PROTEINS; CATALYTIC DOMAIN; ESCHERICHIA COLI; MUTATION; MYOSIN LIGHT CHAINS; MYOSIN-LIGHT-CHAIN KINASE; MYOSINS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS;

EID: 77449136830     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1002/iub.266     Document Type: Article

References (23)

1. Bárány, M. (1979) Biochemistry of Smooth Muscle Contraction. Academic Press, San Diego.
2. Kamm, K. E. and Stull, J. T. (2001) Dedicated myosin light chain kinase with diverse cellular functions. J. Biol. Chem. 276, 4527-4530.
3. Nakamura, A., Xie, C., Zhang, Y., Gao, Y., Wang, H., Ye, L., Kishi, H., Yoshiyama, S., Hayakawa, K., Ishikawa, R., and Kohama, K. (2008) Role of non-kinase activity of myosin light-chain kinase in regulating smooth muscle contraction, a review dedicated to Dr. Setsuro Ebashi. Biochem. Biophys. Res. Commun. 369, 135-143.
4. Gao, Y., Ye, L.-H., Kishi, H., Okagaki, T., Samizo, K., Nakamura, A., and Kohama, K. (2001) Myosin light chain kinase as a multifunctional regulatory protein of smooth muscle contraction. IUBMB Life 51, 337-344. (Pubitemid 33096653)
5. Olson, N. J., Pearson, R. B., Needleman, D. S., Hurwitz, M. Y., Kemp, B. E., and Means, A. R. (1990) Regulatory and structural motifs of chicken gizzard myosin light chain kinase. Proc. Natl. Acad. Sci. USA 87, 2284-2288.
6. Kobayashi, H., Inoue, A., Mikawa, T., Kuwayama, H., Hotta, Y., Masaki, T., and Ebashi, S. (1992) Isolation of cDNA for bovine stomach 155 kDa protein exhibiting myosin light chain kinase activity. J. Biochem. 112, 786-791. (Pubitemid 23010130)
7. Ye, L.-H., Hayakawa, K., Kishi, H., Imamura, M., Nakamura, A., Okagaki, T., Takagi, T., Iwata, A., Tanaka, T., and Kohama, K. (1997) The structure and function of the actin-binding domain of myosin light chain kinase of smooth muscle. J. Biol. Chem. 272, 32182-32189.
8. Smith, L., Su, X., Lin, P., Zhi, G., and Stull, J. T. (1999) Identification of a novel actin binding motif in smooth muscle myosin light chain kinase. J. Biol. Chem. 274, 29433-29438.
9. Matsushima, S., Ito, M., Hartshorne, D. J., and Guerrieno, V. Jr. Auto-inhibition of Myosin Light Chain Kinase (1995) In Regulation of the Contractile Cycle in Smooth Muscle. (Nakano, T. and Hartshorne, D. J., eds.). pp. 131-137, Springer, Tokyo.
10. Kohama, K., Okagaki, T., Hayakawa, K., Lin, Y., Ishikawa, R., Shimmen, T., and Inoue, A. (1992) A novel regulatory effect of myosin light chain kinase from smooth muscle on the ATP-dependent interaction between actin and myosin. Biochem. Biophys. Res. Commun. 184, 1204-1211.
11. Samizo, K., Okagaki, T., and Kohama, K. (1999) Inhibitory effect of phosphorylated myosin light chain kinase on the ATP-dependent actin-myosin interaction. Biochem. Biophys. Res. Commun. 261, 95-99.
12. Lukas, T. J., Burgess, W. H., Prendergast, F. G., Lau, W., and Watterson, D. M. (1986) Calmodulin binding domains: characterization of a phosphorylation and calmodulin binding site from myosin light chain kinase. Biochemistry 25, 1458-1464. (Pubitemid 16048124)
13. Spudich, J. A. and Watt, S. (1971) The regulation of rabbit skeletal muscle contraction. I. Biochemical studies of the interaction of the tropomyosin-troponin complex with actin and the proteolytic fragments of myosin. J. Biol. Chem. 246, 4866-4871.
14. Kohama, K. (1980) Heterogeneity of amino acid incorporation rate in adult skeletal muscle actin. J. Biochem. 87, 997-999.
15. Kuwayama, H. and Ebashi, S. (1988) Isolation from bovine brain of 155kDa component exhibiting myosin light chain kinase activity. J. Biochem. 104, 858-861. (Pubitemid 23010130)
16. Adelstein, R. S. and Klee, C. B. (1981) Purification and characterization of smooth muscle myosin light chain kinase. J. Biochem. 256, 7501-7509.
17. Hayakawa, K., Okagaki, T., Higashi Fujime, S., and Kohama, K. (1994) Bundling of actin filaments by myosin light chain kinase from smooth muscle. Biochem. Biophys. Res. Commun. 199, 786-791.
18. Nakamura, A., Hanyuda, Y., Okagaki, T., Takagi, T., and Kohama, K. (2005) A calmodulin-dependent protein kinase from lower eukaryote Physarum polycephalum. Biochem. Biophys. Res. Commun. 328, 838-844.
19. Kodama, T., Fukui, K., and Kometani, K. (1986) The initial phosphate burst in ATP hydrolysis by myosin and subfragment-1 as studied by a modified malachite green method for determination of inorganic phosphate. J. Biochem. 99, 1465-1472. (Pubitemid 16033517)
20. Okagaki, T., Higashi Fujime, S., Ishikawa, R., Takano Ohmuro, H., and Kohama, K. (1991) In vitro movement of actin filaments on gizzard smooth muscle myosin: reguirement of phosphorylation of myosin light chain and effects of tropomyosin and caldesmon. J. Biochem. 109, 858-866.
21. Ishikawa, R., Yamashiro, S., and Matsumura, F. (1989) Differential modulation of actin-severing activity of gelsolin by multiple isoforms of cultured rat cell tropomyosin. Potentiation of protective ability of tropomyosins by 83-kDa nonmuscle caldesmon. J. Biol. Chem. 264, 7490-7497.
22. Perrie, W. T. and Perry, S. V. (1970) An electrophoretic study of the low molecular-weight components of myosin. J. Biochem. 119, 31-38.
23. Numata, T., Katoh, T., and Yazawa, M. (2001) Functional role of the C-terminal domain of smooth muscle myosin light chain kinase on the phosphorylation of smooth muscle myosin. J. Biochem. 129, 437-444. (Pubitemid 32304119)