Discrepancies between APTT results determined with different evaluation modes on automated coagulation analyzers

International Journal of Laboratory Hematology

Volumn 32, Issue 1 PART.2, 2010, Pages 33-39

  Milos, M ^a   Coen Herak, D ^a   Zadro, R ^a  

^a KBC Zagreb   (Croatia)

Author keywords

Activated partial thromboplastin time; Coagulation analyzers; Evaluation mode; Reaction curve; Visual analysis

Indexed keywords

ACTIN; REAGENT;

ARTICLE; AUTOANALYZER; BLOOD ANALYSIS; BLOOD CLOTTING; BLOOD CLOTTING TEST; BLOOD CLOTTING TIME; COAGULOMETER; CONTROLLED STUDY; DIAGNOSTIC PROCEDURE; FRIEDMAN TEST; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL;

AUTOMATION; BLOOD COAGULATION DISORDERS; BLOOD COAGULATION TESTS; HUMANS; PARTIAL THROMBOPLASTIN TIME; REFERENCE STANDARDS;

EID: 77449133315     PISSN: 17515521     EISSN: 1751553X     Source Type: Journal    
DOI: 10.1111/j.1751-553X.2008.01111.x     Document Type: Article

References (9)

1. Bland J.M. & Altman D.J. (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1, 307-310.
2. Braun P.J., Thomas B.G., Andrew G.S., Beck L.R., Gooch S.A., Swan R.J. & Fischer T.J. (1997) Properties of optical data from activated partial thromboplastin time and prothrombin time assays. Thrombosis and Haemostasis 78, 1079-1087.
3. Givens T.B., Braun P.J. & Fischer T.J. (1996) Prediciting the presence of plasma heparin using neural networks to analyze coagulation screening assay optical profiles. Computational Biological Medicine 26, 463-476.
4. Mair G., Dunhill S. & Tiplady C. (2007) Prognostic implications of a biphasic waveform for APTT analysis in a district general hospital. International Journal of Laboratory Hematology doi:10.1111/ j.1751-553X.2008. 01111.x.
5. Shima M., Matsumoto T., Fukuda K., Kubota Y., Tanaka I., Nishiya K., Giles A.R. & Yoshioka A. (2002) The utility of activated partial thromboplastin time (aPTT) clot waveform analysis in the investigation of hemophilia A patients with very low levels of factor VIII activity (FVIII:C). Thrombosis and Haemostasis 87, 436-441.
6. Smith E.Y., Charles L.A. & Van Cott E.M. (2004) Biphasic activated partial thromboplastin time waveform and adverse events in non-intensive care unitpatients. American Journal of Clinical Pathology 121, 138-141.
7. Su Z., Braun P.J., Klemp K.F., Baker K.R., Thames E.H. & Ortel T.L. (2002) Abnormal optical waveform profiles in coagulation assays from patients with antiphospholipid antibodies. Blood Coagulation & Fibrinolysis 13, 7-17.
8. Thomas L.C. & Sochynsky C.L. (1999) Multiple measuring modes of coagulation instruments. Clinical Hemostasis Review 13, 6-8.
9. Toh C.H. & Giles A.R. (2002) Waveform analysis of clotting test optical profiles in the diagnosis and management of disseminated intravascular coagulation (DIC). Clinical and Laboratory Haematology 24, 321-327.