Crystsl structure of the DNA gyrase gyra n-terminal domain from mycobacterium tuberculosis

Proteins: Structure, Function and Bioinformatics

Volumn 78, Issue 2, 2010, Pages 492-495

  Tretter, Elsa M ^a   Schoeffler, Allyn J ^a   Weisfield, Shellie R ^a   Berger, James M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Antibiotic resistance; Breakage reunion domain; Dna topology; Gyrase; Mycobacterium tuberculosis; Topoisomerase

Indexed keywords

DNA TOPOISOMERASE (ATP HYDROLYSING) A; DNA TOPOISOMERASE (ATP HYDROLYSING);

AMINO TERMINAL SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; STRUCTURE ANALYSIS; X RAY DIFFRACTION; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; ESCHERICHIA COLI; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

MYCOBACTERIUM TUBERCULOSIS;

CRYSTALLOGRAPHY, X-RAY; DNA GYRASE; ESCHERICHIA COLI; MODELS, MOLECULAR; MYCOBACTERIUM TUBERCULOSIS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY;

EID: 77449119634     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.22600     Document Type: Article

References (18)

1. Schoeffler AJ, Berger JM. DNA topoisomerases: harnessing and. constraining energy to govern chromosome topology. Q Rev Biophys 2008;41:41-101.
2. Mizuuchi K, Fisher LM, O'Dea MH, Geliert M. DNA gyrase action involves the introduction of transient double-strand breaks into DNA. Proc Natl Acad Sci U S A 1980;77:1847-1851.
3. Tse YC, Kirkegaard K, Wang JC. Covalent bonds between protein and DNA. Formation of phosphotyrosine linkage between certain DNA topoisomerases and DNA. J Biol Chem 1980;255:5560-5565.
4. Hooper DC. Mechanisms of fluoroquinolone resistance. Drug Resist Update 1999;2:38-55.
5. Organization WH. Global tuberculosis control-epidemiology, strategy, financing. WHO report 2009 2008;WHO/HTM/TB/2009. 411.
6. Kapust RB, Tozser J, Fox JD, Anderson DE, Cherry S, Copeland TD, Waugh DS. Tobacco etch virus protease: mechanism of autolysis and rational design of stable mutants with wild-type catalytic proficiency. Protein Eng 2001;14:993-1000.
7. MacDowell AA, Celestre RS, Howells M, McKinney W, Krupnick J, Cambie D, Domning EE, Duarte RM, Kelez N, Plate DW, Cork CW, Earnest TN, Dickert J, Meigs G, Ralston C, Holton JM, Alber T, Berger JM, Agard DA, Padmore HA. Suite of three protein crystallography beamlines with single superconducting bend magnet as the source. J Synchrotron Radiat 2004;11:447-455.
8. Z Otwinowski WM, Processing of X-ray diffraction data collected in the oscillation mode. Methods Enzymol 1997;276:307-326.
9. Cabral JHM, Jackson AP, Smith CV, Shikotra N, Maxwell A, Liddington RC. Crystal, structure of the breakage-reunion domain of DNA gyrase. Nature 1997;388:903-906.
10. McCoy AJ, Grosse-Kunstleve RW, Adams PD, Winn MD, Storoni LC, Read RJ. Phaser crystallographic software. J Appl Cryst 2007;40:658-674.
11. Adams PD, Grosse-Kunstleve RW, Hung L-W, Ioerger TR, McCoy AJ, Moriarty NW, Read RJ, Sacchettini JC, Sauter NK, Tsrwilliger TC. PHENIX: building new software for automated crystallographic structure determination, Acta. Cryst 2002;58:1948-1954.
12. Emsley P, Cowtan K. Coot; model-building tools for molecular graphics. Acta Cryst 2004;60:2126-2132.
13. Painter J, Merritt EA. TLSMD web server for the generation of multi-group TLS models. J Appl Cryst. 2006;39:109-111.
14. Simon C. Lovell IWD, W. Bryan Arendall III, Paul I. W. de Bakker J. Michael Word, Michael G. Prisant, Jane S. Richardson David C. Richardson. Structure validation by Calpha geometry: φ, ψ and Cβ deviation. Proteins Structure Function Genetics 2003;50:437-450.
15. Lapouogov I, Sohi MK, Veselkov DA, Pan XS, Sawhney R, Thompson AW, McAuley KE, Fisher LM, Sanderson MR. Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases. Nat Struct Mol Biol 2009;16:667-669.
16. Dong KC, Berger JM. Structural basis for gate-DNA recognition and bending by type IIA topoisomerases. Nature 2007;450:1201-1205.
17. Corbett KD, Schoeffler AJ, Thomsen ND, Berger JM. The structural basis for substrate specificity in DNA topoisomerase IV. J Mol Biol 2005;351:545-561.
18. DeLano WL. The PyMOL Molecular Graphics System, DeLano Scientific, Palo Alto, CA, 2002.