A comparative study of dexmedetomidine with midazolam and midazolam alone for sedation during elective awake fiberoptic intubation

Journal of Clinical Anesthesia

Volumn 22, Issue 1, 2010, Pages 35-40

  Bergese, Sergio D ^a   Patrick Bender, Stephen ^a   McSweeney, Thomas D ^a   Fernandez, Soledad ^a   Dzwonczyk, Roger ^a   Sage, Kevin ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

Awake fiberoptic intubation; Dexmedetomidine; Midazolam; Sedation

Indexed keywords

DEXMEDETOMIDINE; GLYCOPYRRONIUM BROMIDE; LOCAL ANESTHETIC AGENT; MIDAZOLAM;

ADULT; AGED; AIRWAY; ANESTHESIOLOGICAL TECHNIQUES; ARTICLE; AWAKE FIBEROPTIC INTUBATION; CLINICAL ASSESSMENT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG DOSE TITRATION; FEMALE; FIBER OPTICS; HUMAN; INTUBATION; LOCAL ANESTHESIA; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PREMEDICATION; PRIORITY JOURNAL; RAMSAY SEDATION SCALE; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; SCORING SYSTEM; SEDATION;

ADULT; AGED; AGED, 80 AND OVER; CONSCIOUS SEDATION; DEXMEDETOMIDINE; DOUBLE-BLIND METHOD; FEMALE; FIBER OPTIC TECHNOLOGY; HUMANS; HYPNOTICS AND SEDATIVES; INTUBATION, INTRATRACHEAL; MALE; MIDAZOLAM; MIDDLE AGED; YOUNG ADULT;

EID: 77449113451     PISSN: 09528180     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jclinane.2009.02.016     Document Type: Article

References (20)

1. Rosenblatt W.H. Airway management. In: Barash P.G., Cullen B.F., Stoelting R.K., et al. (Eds). Clinical Anesthesia. 4th ed. (2001), Lippincott Williams & Wilkins, Philadelphia 595-638
2. Ovassapian A. Fiberoptic endoscopy and the difficult airway. 2nd ed. (1996), Lippincott-Raven Publishers, Philadelphia 61-69
3. Bailey P.L., Pace N.L., Ashburn M.A., Moll J.W., East K.A., and Stanley T.H. Frequent hypoxemia and apnea after sedation with midazolam and fentanyl. Anesthesiology 73 (1990) 826-830
4. Kamibayashi T., and Maze M. Clinical uses of alpha2-adrenergic agonists. Anesthesiology 93 (2000) 1345-1349
5. Ebert T.J., Hall J.E., Barney J.A., Uhrich T.D., and Colinco M.D. The effects of increasing plasma concentrations of dexmedetomidine in humans. Anesthesiology 93 (2000) 382-394
6. Venn R.M., Hell J., and Grounds R.M. Respiratory effects of dexmedetomidine in the surgical subject requiring intensive care. Crit Care Med 4 (2000) 302-308
7. Grant S.A., Breslin D.S., MacLeod D.B., Gleason D., and Martin G. Dexmedetomidine infusion for sedation during fiberoptic intubation: a report of three cases. J Clin Anesth 16 (2004) 124-126
8. Chernik D.A., Gillings D., Laine H., et al. Validity and reliability of the Observer's Assessment of Alertness/Sedation Scale: study with intravenous midazolam. J Clin Psychopharmacol 10 (1990) 244-251
9. Ambuel B., Hamlett K.W., Marx C.M., and Blumer J.L. Assessing distress in pediatric intensive care environments: the COMFORT scale. J Pediatr Psychol 17 (1992) 95-109
10. Avitsian R., Lin J., Lotto M., and Ebrahim Z. Dexmedetomidine and awake fiberoptic intubation for possible cervical spine myelopathy. J Neurosurg Anesthesiol 17 (2005) 97-99
11. Ramsay M.A., and Luterman D.L. Dexmedetomidine as a total intravenous anesthetic agent. Anesthesiology 101 (2004) 787-790
12. Bhana N., Goa K.L., and McClellan K.J. Dexmedetomidine. Drugs 59 (2000) 263-268
13. Ebert T., and Maze M. Dexmedetomidine: another arrow for the clinician's quiver. Anesthesiology 101 (2004) 568-570
14. Bloor B.C., Ward D.S., Belleville J.P., and Mervyn M. Effects of intravenous dexmedetomidine in humans II. Hemodynamic changes. Anesthesiology 77 (1992) 1134-1142
15. Jorden V.S., Pousman R.M., Sanfor M.M., Thorborg P.A., and Hutchens M.P. Dexmedetomidine overdose in the perioperative setting. Ann Pharmacother 38 (2004) 803-807
16. Venn R.M., and Grounds R.M. Comparison between dexmedetomidine and propofol for sedation in the intensive care unit: patient and clinician perceptions. Br J Anaesth 87 (2001) 684-690
17. Peden C.J., Cloote A.H., Stratford N., and Prys-Roberts C. The effect of intravenous dexmedetomidine premedication on the dose requirement of propofol to induce loss of consciousness in patients receiving alfentanil. Anaesthesia 56 (2001) 408-413
18. Porro G.B., Garoni S., Parente F., and Lazzaroni M. Midazolam versus diazepam as premedication for upper gastrointestinal endoscopy: a randomized, double-blind, crossover study. Gastroint Endosc 34 (1988) 252-254
19. Hall J.E., Uhrich T.D., Barney J.A., Arain S.R., and Ebert T.J. Sedative, amnestic, and analgesic properties of small dose dexmedetomidine infusions. Anesth Analg 90 (2000) 699-705
20. Ustun Y., Gunduz M., Erdogan O., and Bendlidayi M.E. Dexmedetomidine versus midazolam in outpatient third molar surgery. J Oral Maxillofac Surg 64 (2006) 1353-1358