The Impact of Radiation Dose and Fractionation on Outcomes for Limited-Stage Small-Cell Lung Cancer

International Journal of Radiation Oncology Biology Physics

Volumn 76, Issue 4, 2010, Pages 1121-1126

  Tomita, Natsuo ^a   Kodaira, Takeshi ^a   Hida, Toyoaki ^a   Tachibana, Hiroyuki ^a   Nakamura, Tatsuya ^a   Nakahara, Rie ^a   Inokuchi, Haruo ^a  

^a AICHI CANCER CENTER HOSPITAL   (Japan)

Author keywords

Accelerated hyperfractionation; Fractionation; Radiation dose; Radiation therapy; Small cell lung cancer

Indexed keywords

ACCELERATED HYPERFRACTIONATION; HYPERFRACTIONATION; RADIATION DOSE; RADIATION THERAPY; SMALL-CELL LUNG CANCER;

BIOLOGICAL ORGANS; DOSIMETRY; RADIATION;

RADIOTHERAPY;

CARBOPLATIN; CISPLATIN; ETOPOSIDE; IRINOTECAN;

ADULT; AGED; ARTICLE; CANCER CHEMORADIOTHERAPY; CANCER COMBINATION CHEMOTHERAPY; CANCER CONTROL; CANCER RADIOTHERAPY; CANCER STAGING; CONTROLLED STUDY; FEMALE; FOLLOW UP; HUMAN; LUNG SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; MULTIPLE CYCLE TREATMENT; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; RADIATION DOSE; RADIATION DOSE FRACTIONATION; RADIATION PNEUMONIA; SURVIVAL TIME; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; COMBINED MODALITY THERAPY; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; RADIOTHERAPY; RADIOTHERAPY DOSAGE; RETROSPECTIVE STUDIES; SMALL CELL LUNG CARCINOMA; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 77449111120     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2009.03.069     Document Type: Article

References (18)

1. Komaki R. Combined treatment for limited small cell lung cancer. Semin Oncol 30 (2003) 56-70
2. Turrisi III A.T., Kim K., Blum R., et al. Twice-daily compared with once-daily thoracic radiotherapy in limited small-cell lung cancer treated concurrently with cisplatin and etoposide. N Engl J Med 340 (1999) 265-271
3. Movsas B., Moughan J., Komaki R., et al. Radiotherapy patterns of care study in lung carcinoma. J Clin Oncol 21 (2003) 4553-4559
4. Uno T., Sumi M., Ishihara Y., et al. Changes in patterns of care for limited-stage small-cell lung cancer: Results of the 99-01 patterns of care study-a nationwide survey in Japan. Int J Radiat Oncol Biol Phys 71 (2007) 414-419
5. Demiral A.N., Alicikus Z.A., Isil Ugur V., et al. Patterns of care for lung cancer in radiation oncology departments of Turkey. Int J Radiat Oncol Biol Phys 72 (2008) 1530-1537
6. De Ruysscher D., Bremer R.H., Koppe F., et al. Omission of elective node irradiation on basis of CT-scans in patients with limited disease small cell lung cancer: A phase II trial. Radiother Oncol 80 (2006) 307-312
7. Nakamura T., Fuwa N., Kodaira T., et al. Clinical outcome of stage III non-small-cell lung cancer patients after definitive radiotherapy. Lung 186 (2008) 91-96
8. Auperin A., Arriagada R., Pignon J.P., et al. Prophylactic cranial irradiation for patients with small-cell lung cancer in complete remission. Prophylactic Cranial Irradiation Overview Collaborative Group. N Engl J Med 341 (1999) 476-484
9. Therasse P., Arbuck S.G., Eisenhauer E.A., et al. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 92 (2000) 205-216
10. Common terminology criteria for adverse events, version 3.0. Available online at: http://www.jcog.jp/
11. Tsujino K., Hirota S., Kotani Y., et al. Radiation pneumonitis following concurrent accelerated hyperfractionated radiotherapy and chemotherapy for limited-stage small-cell lung cancer: Dose-volume histogram analysis and comparison with conventional chemoradiation. Int J Radiat Oncol Biol Phys 64 (2006) 1100-1105
12. Carney D.N. Lung cancer biology. Semin Radiat Oncol 5 (1995) 4-10
13. Schild S.E., Bonner J.A., Shanahan T.G., et al. Long-term results of a phase III trial comparing once-daily radiotherapy with twice-daily radiotherapy in limited-stage small-cell lung cancer. Int J Radiat Oncol Biol Phys 59 (2004) 943-951
14. Komaki R., Swann R.S., Ettinger D.S., et al. Phase I study of thoracic radiation dose escalation with concurrent chemotherapy for patients with limited small-cell lung cancer: Report of Radiation Therapy Oncology Group (RTOG) protocol 97-12. Int J Radiat Oncol Biol Phys 62 (2005) 342-350
15. Roof K.S., Fidias P., Lynch T.J., et al. Radiation dose escalation in limited-stage small-cell lung cancer. Int J Radiat Oncol Biol Phys 57 (2003) 701-708
16. Baas P., Belderbos J.S., Senan S., et al. Concurrent chemotherapy (carboplatin, paclitaxel, etoposide) and involved-field radiotherapy in limited stage small cell lung cancer: A Dutch multicenter phase II study. Br J Cancer 94 (2006) 625-630
17. Woll P.J., Thatcher N., Lomax L., et al. Use of hematopoietic progenitors in whole blood to support dose-dense chemotherapy: A randomized phase II trial in small-cell lung cancer patients. J Clin Oncol 19 (2001) 712-719
18. Socinski M.A., and Bogart J.A. Limited-stage small-cell lung cancer: The current status of combined-modality therapy. J Clin Oncol 25 (2007) 4137-4145