Disastrous physiological effects of saline on the cell membrane demonstrated in cardiac cells

Scandinavian Cardiovascular Journal

Volumn 38, Issue 5, 2004, Pages 300-306

  Arlock, Per ^a   Wohlfart, B ^a   Sjoberg T ^a   Steen, S ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Action potential; Cardiac muscle; Contractility; Myocytes; Saline; Voltage clamp

Indexed keywords

SODIUM CHLORIDE;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; CELL DEATH; CELL MEMBRANE; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; EXPOSURE; GUINEA PIG; HEART CONTRACTION; HEART MUSCLE CELL; HEART MUSCLE FIBER MEMBRANE STEADY POTENTIAL; HEART MUSCLE REPERFUSION; HEART PAPILLARY MUSCLE; HEART VENTRICLE WALL; IN VITRO STUDY; MEMBRANE CURRENT; MUSCLE FUNCTION; NONHUMAN; PRIORITY JOURNAL; RECORDING; TEMPERATURE MEASUREMENT;

ACTION POTENTIALS; ANIMALS; CELL MEMBRANE; ELECTROPHYSIOLOGIC TECHNIQUES, CARDIAC; GUINEA PIGS; MUSCLE CONTRACTION; MYOCYTES, CARDIAC; PAPILLARY MUSCLES; SALINE SOLUTION, HYPERTONIC; SODIUM CHLORIDE;

EID: 7744232904     PISSN: 14017431     EISSN: None     Source Type: Journal    
DOI: 10.1080/14017430410021499     Document Type: Article

References (20)

1. Steen S. Preservation of the endothelium in cardiovascular surgery - some practical suggestions - a review. Scand Cardiovasc J 2001; 35: 297-301.
2. 2+]i following extrasystoles in guinea-pig trabeculae microinjected with fluo-3 - a comparison with frog skeletal muscle fibres. Acta Physiol Scand 2000; 169: 1-11.
3. Roscher R, Arlock P, Sjöberg T, Steen S. Effects of dopamine on porcine myocardial action potentials and contractions at 37°C and 32°C. Acta Anaesthesiol Scand 2001; 45: 421-426.
4. Wettwer E, Scholtysik G, Schaad A, et al. Effects of the new class-III anti-arrhythmic drug E-4031 on myocardial contractility and electrophysiological parameters. J Cardiovasc Pharmacol 1991; 17: 480-487.
5. Himmel HM, Amos GJ, Wettwer E, et al. Effects of the calcium sensitizer [+]-EMD 60263 and its enantiomer [-]-EMD 60264 on cardiac ionic currents of guinea-pig and rat ventricular myocytes. J Cardiovasc Pharmacol 1999; 33: 301-308.
6. Beeler GW, Reuter H. The relation between membrane potential, membrane currents and activation of contraction in ventricular myocardial fibres. J Physiol 1970; 207: 211-229.
7. New W, Trautwein W. The ionic nature of slow inward current and its relation to contraction. Pflugers Arch 1972; 334: 24-38.
8. Fedida D, Noble D, Shimoni Y, Spindler AJ. Inward current related to contraction in guinea-pig ventricular myocytes. J Physiol 1987; 385: 565-589.
9. Noble D, Noble SJ, Bett GCL. The role of sodium-calcium exchange during the cardiac action potential. Baltimore Meeting on Sodium-Calcium Exchange, 1991: 334-353.
10. Mullins LJ. The generation of electric currents in cardiac fibers by Na/Ca exchange. Am J Physiol 1979; 236: C103-C110.
11. Kimura J, Noma A, Irisawa H. Na-Ca exchange current in mammalian heart cells. Nature 1986; 319: 596-597.
12. Mechmann S, Port L. Identification of Na-Ca exchange current in single cardiac myocytes. Nature 1986; 319: 596-599.
13. +-channels and control of ventricular repolarization in the heart. Fundam Clin Pharmacol 1993; 7: 19-28.
14. Peper K, Trautwein W. A note on the pacemaker current in Purkinje fibers. Pflugers Arch 1969; 309: 356-361.
15. Fabiato A. Calcium-induced release of calcium from the sarcoplasmic reticulum. J Gen Physiol 1985; 85: 189-320.
16. Eisner DA, Choi HS, Diaz ME, O'Neill SC, Trafford AW. Integrative analysis of calcium cycling in cardiac muscle. Circ Res 2000; 87: 1087-1094.
17. Chapman RA, Tunstall J. The calcium paradox of the heart. Prog Biophys Mol Biol 1987; 50: 67-96.
18. Arlock P, Katzung BG. Effects of sodium substitutes on transient inward current and tension in guinea-pig and ferret papillary muscle. J Physiol 1985; 360: 105-120.
19. Liu B, Arlock P, Wohlfart B, Johansson BW. Temperature effects on the Na and Ca currents in rat and hedgehog ventricular muscle. Cryobiology 1991; 28: 96-104.
20. Cheng H, Lederer WJ, Cannel MB. Calcium-sparks: Elementary events underlying excitation-contraction coupling in heart muscle. Science 1993; 262: 740-744.