Cyclic guanosine monophosphate dependent pathway contributes to human mast cell inhibitory actions of the nitric oxide donor, diethylamine NONOate

European Journal of Pharmacology

Volumn 632, Issue 1-3, 2010, Pages 86-92

  Yip, Kwok H ^a   Huang, Yu ^a   Leung, Fung P ^a   Lau, Hang Y A ^a  

^a Prince of Wales Hospital   (Hong Kong)

Author keywords

Cyclic guanosine monophosphate; Histamine; Human mast cells; Nitric oxide; Soluble guanylyl cyclase

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 3,3 BIS(2 AMINOETHYL) 1 HYDROXY 2 OXOTRIAZENE; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE INHIBITOR; CYTOKINE; GUANYLATE CYCLASE; HISTAMINE; ICOSANOID; IMMUNOGLOBULIN E ANTIBODY; INTERLEUKIN 8; NITRIC OXIDE; RP 8 (4 CHLOROPHENYLTHIO)GUANOSINE 3',5' CYCLIC MONOPHOSPHOROTHIOATE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE RELEASE; DOSE RESPONSE; DRUG ACTIVITY; DRUG SCREENING; GROWTH INHIBITION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANTIBODIES, ANTI-IDIOTYPIC; CELLS, CULTURED; CYCLIC GMP; DOSE-RESPONSE RELATIONSHIP, DRUG; GUANYLATE CYCLASE; HISTAMINE; HUMANS; HYDRAZINES; MAST CELLS; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE DONORS; RECEPTORS, CYTOPLASMIC AND NUCLEAR;

EID: 77349109003     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.01.007     Document Type: Article

References (23)

1. Bidri M., Becherel P.A., Le Goff L., Pieroni L., Guillosson J.J., Debre P., and Arock M. Involvement of cyclic nucleotides in the immunomodulatory effects of nitric oxide on murine mast cells. Biochem. Biophys. Res. Commun. 210 (1995) 507-517
2. Butt E., Eigenthaler M., and Genieser H.G. (Rp)-8-pCPT-cGMPS, a novel cGMP-dependent protein kinase inhibitor. Eur. J. Pharmacol. 269 (1994) 265-268
3. Colasanti M., and Persichini T. Nitric oxide: an inhibitor of NF-kappaB/Rel system in glial cells. Brain Res. Bull. 52 (2000) 155-161
4. Coleman J.W. Nitric oxide in immunity and inflammation. Int. Immunopharmacol. 1 (2001) 1397-1406
5. Davis B.J., Flanagan B.F., Gilfillan A.M., Metcalfe D.D., and Coleman J.W. Nitric oxide inhibits IgE-dependent cytokine production and Fos and Jun activation in mast cells. J. Immunol. 173 (2004) 6914-6920
6. Denninger J.W., and Marletta M.A. Guanylate cyclase and the.NO/cGMP signaling pathway. Biochim. Biophys. Acta 1411 (1999) 334-350
7. Deschoolmeester M.L., Eastmond N.C., Dearman R.J., Kimber I., Basketter D.A., and Coleman J.W. Reciprocal effects of interleukin-4 and interferon-gamma on immunoglobulin E-mediated mast cell degranulation: a role for nitric oxide but not peroxynitrite or cyclic guanosine monophosphate. Immunology 96 (1999) 138-144
8. Friebe A., Mullershausen F., Smolenski A., Walter U., Schultz G., and Koesling D. YC-1 potentiates nitric oxide- and carbon monoxide-induced cyclic GMP effects in human platelets. Mol. Pharmacol. 54 (1998) 962-967
9. Galli S.J. Mast cells and basophils. Curr. Opin. Hematol. 7 (2000) 32-39
10. Gordon J.R., Burd P.R., and Galli S.J. Mast cells as a source of multifunctional cytokines. Immunol. Today 11 (1990) 458-464
11. Kimata M., Inagaki N., Kato T., Miura T., Serizawa I., and Nagai H. Roles of mitogen-activated protein kinase pathways for mediator release from human cultured mast cells. Biochem. Pharmacol. 60 (2000) 589-594
12. Lorentz A., Klopp I., Gebhardt T., Manns M.P., and Bischoff S.C. Role of activator protein 1, nuclear factor-kappaB, and nuclear factor of activated T cells in IgE receptor-mediated cytokine expression in mature human mast cells. J. Allergy Clin. Immunol. 111 (2003) 1062-1068
13. Masini E., Salvemini D., Pistelli A., Mannaioni P.F., and Vane J.R. Rat mast cells synthesize a nitric oxide like-factor which modulates the release of histamine. Agents Actions 33 (1991) 61-63
14. Metcalfe D.D., Baram D., and Mekori Y.A. Mast. Cells. Physiol. Rev. 77 (1997) 1033-1079
15. Reischl I.G., Coward W.R., and Church M.K. Molecular consequences of human mast cell activation following immunoglobulin E-high-affinity immunoglobulin E receptor (IgE-FcepsilonRI) interaction. Biochem. Pharmacol. 58 (1999) 1841-1850
16. Russo C., Zeng D., Prosperini G., Spicuzza L., Guarino F., and Polosa R. Effect of salbutamol on nasal symptoms and mast cell degranulation induced by adenosine 5′ monophosphate nasal challenge. Clin. Exp. Allergy 35 (2005) 1192-1196
17. Salvemini D., Masini E., Pistelli A., Mannaioni P.F., and Vane J. Nitric oxide: a regulatory mediator of mast cell reactivity. J. Cardiovasc. Pharmacol. 17 (1991) S258-S264
18. Schrammel A., Behrends S., Schmidt K., Koesling D., and Mayer B. Characterization of 1H-[1, 2, 4]oxadiazolo[4, 3-a]quinoxalin-1-one as a heme-site inhibitor of nitric oxide-sensitive guanylyl cyclase. Mol. Pharmacol. 50 (1996) 1-5
19. Smolenski A., Burkhardt A.M., Eigenthaler M., Butt E., Gambaryan S., Lohmann S.M., and Walter U. Functional analysis of cGMP-dependent protein kinases I and II as mediators of NO/cGMP effects. Naunyn Schmiedebergs Arch. Pharmacol. 358 (1998) 134-139
20. Stasch J.P., Becker E.M., Alonso-Alija C., Apeler H., Dembowsky K., Feurer A., Gerzer R., Minuth T., Perzborn E., Pleiss U., Schroder H., Schroeder W., Stahl E., Steinke W., Straub A., and Schramm M. NO-independent regulatory site on soluble guanylate cyclase. Nature 410 (2001) 212-215
21. Wang X.S., Yip K.H., Sam S.W., and Lau H.Y. Buffy coat preparation is a convenient source of progenitors for culturing mature human mast cells. J. Immunol. Methods 309 (2006) 69-74
22. Yip K., Leung F., Huang Y., and Lau H. Inhibition of anti-IgE mediated human mast cell activation by NO donors is dependent on their NO release kinetics. Br. J. Pharmacol. 156 (2009) 1279-1286
23. Yip K.H., Huang Y., Waye M.M., and Lau H.Y. Induction of nitric oxide synthases in primary human cultured mast cells by IgE and proinflammatory cytokines. Int. Immunopharmacol. 8 (2008) 764-768