The origins of early breast carcinoma

Seminars in Diagnostic Pathology

Volumn 27, Issue 1, 2010, Pages 62-68

  Tot, Tibor ^a  

^a FALUN HOSPITAL   (Sweden)

Author keywords

Breast; Breast cancer; Disease extent; Early breast cancer; Multifocality; Sick lobe hypothesis

Indexed keywords

ARTICLE; BREAST CARCINOMA; CANCER GRADING; CANCER INVASION; CARCINOMA IN SITU; DIFFERENTIAL DIAGNOSIS; EARLY CANCER; HISTOPATHOLOGY; HUMAN; INVASIVE CARCINOMA; MAJOR CLINICAL STUDY; MALIGNANT TRANSFORMATION; PRECANCER; PRIORITY JOURNAL; TERMINAL DUCTAL LOBULAR UNITS; TUMOR VOLUME;

ADENOCARCINOMA; BREAST NEOPLASMS; CARCINOMA IN SITU; CELL MOVEMENT; CELL NUCLEUS; CELL TRANSFORMATION, NEOPLASTIC; FEMALE; HUMANS; NEOPLASM INVASIVENESS; PRECANCEROUS CONDITIONS;

EID: 77349093050     PISSN: 07402570     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.semdp.2009.12.002     Document Type: Article

References (37)

1. Gallager H.S. Treatment selection in primary breast cancer. Pathologic considerations. Am J Roentgenol 1976, 126:135-138.
2. Nealon T.F., Nkongho A., Grossi C.E., et al. Treatment of early cancer of the breast (T1N0M0 and T2N0M0) on the basis of histologic characteristics. Surgery 1981, 89:279-289.
3. Hartmann W.H. Minimal breast cancer. An update. Cancer 1984, 53(suppl 3):681-684.
4. Tabár L., Chen H.H., Duffy S.W., et al. A novel method for prediction of long-term outcome of women with T1a, T1b and 10-14mm invasive breast cancers: A prospective study. Lancet 2000, 355:429-433.
5. Tabár L., Chen H.T., Yen M.F.A., et al. Mammographic tumor features can predict long-term outcomes reliably in women with 1-14 mm invasive carcinoma. Cancer 2004, 101:1745-1759.
6. Tot T. The limited prognostic value of measuring and grading small breast carcinomas: The whole sick lobe versus the details within it. Med Sci Monit 2006, 12:RA170-RA175.
7. Llombart-Cussac A. Improving decision-making in early breast cancer: Who to treat and how?. Breast Cancer Res Treat 2008, 112(suppl 1):15-24.
8. Holland R., Veling S.H., Mravunac M., et al. Histologic multifocality of Tis, T1-2 breast carcinomas. Cancer 1985, 56:979-990.
9. Faverly D.R.G., Henricks J.H.C.L., Holland R. Breast carcinoma of limited extent. Frequency, radiologic-pathologic characteristics, and surgical margin requirements. Cancer 2001, 91:647-659.
10. Tot T. The clinical relevance of the distribution of the lesions in 500 consecutive breast cancer cases documented in large-format histological sections. Cancer 2007, 110:2551-2560.
11. Tot T. The metastastic capacity of multifocal breast carcinomas: Extensive tumors versus tumors of limited extent. Hum Pathol 2009, 40:199-205.
12. Tot T., Pekár G.y., Hofmeyer S., et al. The distribution of lesions in 1-14-mm invasive breast carcinomas and its relation to metastatic potential. Virchows Arch 2009, 455:109-115.
13. Dawson F.K. Carcinoma in the mammary lobule and its origin. Edinb Med J 1933, 40:57-82.
14. Wellings S.R., Jensen H.M., Marcum R.G. An atlas of subgross pathology of the human breast with special reference to possible precancerous lesions. J Natl Cancer Inst 1975, 55:231-273.
15. Cheatle G.L., Cutler M. Tumors of the Breast 1931, Edward Arnoled & CO, London, United Kingdom.
16. Azzopardi J.G. Problems in Breast Pathology 1979, WB Saunders, London, Philadelphia, Toronto, pp 104-107.
17. Tot T., Tabár L., Dean P.B. Practical Breast Pathology 2002, Thieme, Stuttgart, New York.
18. Tabár L., Tot T., Dean P.B. Breast Cancer: The Art and Science of Early Detection with Mammography 2005, Thieme, Stuttgart, New York.
19. Tot T., Tabár L. Radiologic-pathologic correlation of ductal carcinoma in situ of the breast using two- and three-dimensional large histologic sections. Semin Breast Dis 2005, 8:144-151.
20. Liu S., Ginestier C., Charafe-Jauffret E., et al. BRCA1 regulates human mammary stem/progenitor cell fate. Proc Natl Acad Sci USA 2008, 105:1680-1685.
21. Villadsen R., Fridriksdottir A.J., Ronnov-Jenssen L., et al. Evidence for stem cell hierarchy in the adult human breast. J Cell Biol 2007, 177:87-101.
22. Oakes S.R., Hilton H.N., Ormandy C.J. The alveolar switch: Coordinating the proliferative cues and cell fate decisions that drive the formation of lobuloalveoli from ductal epithelium. Breast Cancer Res 2006, 8:207-216.
23. Reya T., Morrison S.J., Clarke M.F., et al. Stem cells, cancer, and cancer stem cells. Nature 2001, 414:105-111.
24. Al-Hajj M., Wicha M.S., Benito-Hernandez A., et al. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 2003, 100:3983-3988.
25. Lakhani S.R., Chaggar R., Davies S., et al. Genetic alterations in "normal" luminal and myoepithelial cells of the breast. J Pathol 1999, 189:496-503.
26. Tsai Y.C., Lu Y., Nichols P.W., et al. Contiguous patches of normal human mammary epithelium derived from a single stem cell: Implications for breast carcinogenesis. Cancer Res 1996, 56:402-404.
27. Heaphy C.M., Griffith J.K., Bisoffi M. Mammary field cancerization: Molecular evidence and clinical importance. Breast Cancer Res Treat 2009, 118:229-239.
28. Agelopoulos K., Buerger H., Brandt B. Allelic imbalance of the EGFR gene as key event in breast cancer progression-The concept of committed progenitor cells. Curr Cancer Drug Targets 2008, 8:431-445.
29. Tot T. DCIS, cytokeratins and the theory of the sick lobe. Virchows Arch 2005, 447:1-8.
30. Eusebi V., Feudale E., Foschini M.P., et al. Long-term follow-up of in situ carcinoma of the breast. Semin Diagn Pathol 1994, 11:223-235.
31. Fechner R.E. Ductal carcinoma involving the lobule of the breast: A source of confusion with lobular carcinoma in situ. Cancer 1971, 28:274-281.
32. Tot T. The theory of the sick lobe and the possible consequences. Int J Surg Pathol 2007, 15:369-375.
33. Foschini M.P., Righi A., Cucchi M.C., et al. The impact of large sections and 3D technique on the study of lobular in situ and invasive carcinoma of the breast. Virchows Arch 2006, 448:256-261.
34. Foschini M.P., Flamminio F., Miglio R., et al. The impact of large sections on the study of in situ and invasive duct carcinoma of the breast. Hum Pathol 2007, 38:1736-1743.
35. Going J.J., Mohun T.J. Human breast duct anatomy, the "sick lobe" hypothesis and intraductal approaches to breast cancer. Breast Cancer Res Treat 2006, 97:285-291.
36. Trichopoulos D. Hypothesis: Does breast cancer originate in utereo?. Lancet 1990, 335:939-940.
37. Xue F., Michels K.B. Intrauterine factors and risk of breast cancer: A systemic review and meta-analysis of current evidence. Lancet Oncol 2007, 8:1088-1100.