Absence of mutagenic effects of a particular Symphytum officinale L. liquid extract in the bacterial reverse mutation assay

Phytotherapy Research

Volumn 24, Issue 3, 2010, Pages 466-468

  Benedek, Birgit ^a   Ziegler, Andreas ^a   Ottersbach, Peter ^b  

^a PhytoLab GmbH   (Germany)

^b Merck Selbstmedikation GmbH   (Germany)

Author keywords

Ames test; Comfrey; Genotoxicity; Mutagenicity; Pyrrolizidine alkaloids; Symphytum officinale L.

Indexed keywords

COMFREY EXTRACT; KYTTA PLASMA; KYTTA SALBE; UNCLASSIFIED DRUG;

AMES TEST; ARTICLE; COMFREY; CONTROLLED STUDY; GENE MUTATION; GENOTOXICITY; LIVER MICROSOME; MALE; METABOLIC ACTIVATION; MUTAGENIC ACTIVITY; NONHUMAN; PLANT ROOT; RAT; SALMONELLA TYPHIMURIUM;

COLONY COUNT, MICROBIAL; COMFREY; MUTAGENICITY TESTS; MUTAGENS; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; SALMONELLA TYPHIMURIUM;

BACTERIA (MICROORGANISMS); MAMMALIA; SALMONELLA TYPHIMURIUM; SYMPHYTUM; SYMPHYTUM OFFICINALE;

EID: 77349091859     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3000     Document Type: Article

References (5)

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5. OECD. 1997. OECD guideline for testing of chemicals. Bacterial reverse mutation test. OECD Test Guideline 471.