Optimized cannula design and placement for convection-enhanced delivery in rat striatum

Journal of Neuroscience Methods

Volumn 187, Issue 1, 2010, Pages 46-51

  Yin, Dali ^a   Forsayeth, John ^a   Bankiewicz, Krystof S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Convection enhanced delivery; MRI; Rat; Stepped cannula; Striatum

Indexed keywords

AGAROSE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; TRYPAN BLUE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN; CANNULA; CONTROLLED STUDY; CONVECTION ENHANCED DELIVERY; CORPUS STRIATUM; DISTRIBUTION VOLUME; DRUG DISTRIBUTION; EXPERIMENTAL RAT; GEL; MALE; NONHUMAN; PRIORITY JOURNAL; PUTAMEN; RAT; STEREOTACTIC TREATMENT;

ANIMALS; CATHETERIZATION; CONVECTION; CORPUS STRIATUM; DRUG DELIVERY SYSTEMS; EQUIPMENT DESIGN; GELS; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; IMMUNOHISTOCHEMISTRY; MALE; MODELS, NEUROLOGICAL; PUTAMEN; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; SEPHAROSE; TRYPAN BLUE;

EID: 77249179125     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2009.12.008     Document Type: Article

References (14)

1. Bobo R.H., Laske D.W., Akbasak A., Morrison P.F., Dedrick R.L., Oldfield E.H. Convection-enhanced delivery of macromolecules in the brain. Proc Natl Acad Sci USA 1994, 91:2076-2080.
2. Chen M.Y., Lonser R.R., Morrison P.F., Governale L.S., Oldfield E.H. Variables affecting convection-enhanced delivery to the striatum: a systematic examination of rate of infusion, cannula size, infusate concentration, and tissue-cannula sealing time. J Neurosurg 1999, 90:315-320.
3. Gill S.S., Patel N.K., Hotton G.R., O'Sullivan K., McCarter R., Bunnage M., et al. Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease. Nat Med 2003, 9:589-595.
4. Johnson E.M., Berk D.A., Jain R.K., Deen W.M. Diffusion and partitioning of proteins in charged agarose gels. Biophys J 1995, 68:1561-1568.
5. Krauze M.T., McKnight T.R., Yamashita Y., Bringas J., Noble C.O., Saito R., et al. Real-time visualization and characterization of liposomal delivery into the monkey brain by magnetic resonance imaging. Brain Res Brain Res Protoc 2005.
6. Krauze M.T., Saito R., Noble C., Tamas M., Bringas J., Park J.W., et al. Reflux-free cannula for convection-enhanced high-speed delivery of therapeutic agents. J Neurosurg 2005, 103:923-929.
7. Kunwar S. Convection enhanced delivery of IL13-PE38QQR for treatment of recurrent malignant glioma: presentation of interim findings from ongoing phase 1 studies. Acta Neurochir 2003, (Suppl. 88):105-111.
8. Lidar Z., Mardor Y., Jonas T., Pfeffer R., Faibel M., Nass D., et al. Convection-enhanced delivery of paclitaxel for the treatment of recurrent malignant glioma: a phase I/II clinical study. J Neurosurg 2004, 100:472-479.
9. Nicholson C., Sykova E. Extracellular space structure revealed by diffusion analysis. Trends Neurosci 1998, 21:207-215.
10. Sanftner L.M., Sommer J.M., Suzuki B.M., Smith P.H., Vijay S., Vargas J., et al. AAV2-mediated gene delivery to monkey putamen: evaluation of an infusion device and delivery parameters. Exp Neurol 2005, 194:476-483.
11. Sykova E. Diffusion properties of the brain in health and disease. Neurochem Int 2004, 45:453-466.
12. Szerlip N.J., Walbridge S., Yang L., Morrison P.F., Degen J.W., Jarrell S.T., et al. Real-time imaging of convection-enhanced delivery of viruses and virus-sized particles. J Neurosurg 2007, 107:560-567.
13. Varenika V., Dickinson P., Bringas J., LeCouteur R., Higgins R., Park J., et al. Detection of infusate leakage in the brain using real-time imaging of convection-enhanced delivery. J Neurosurg 2008, 109:874-880.
14. Yin D., Valles F.E., Fiandaca M.S., Bringas J., Gimenez F., Berger M.S., et al. Optimal region of the putamen for image-guided convection-enhanced delivery of therapeutics in human and non-human primates. Neuroimage 2009.