Approaches to efficient production of recombinant angiogenesis inhibitor rhVEGI-192 and characterization of its structure and antiangiogenic function

Protein Science

Volumn 19, Issue 3, 2010, Pages 449-457

  Chen, Xu ^a   Wu, Jueheng ^a,b   Liu, Hanning ^a   He, Zhenjian ^a,b   Gu, Minghui ^a   Wang, Ning ^a   Ma, Jianda ^a   Hu, Jieping ^a   Xia, Lei ^a   He, Haipeng ^a   Yuan, Jie ^a,b   Li, Jun ^a,b   Li, Luyuan ^c   Li, Mengfeng ^a,b   Zhu, Xun ^a,b  

^a SUN YAT SEN UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c NANKAI UNIVERSITY   (China)

Author keywords

Angiogenesis; Autoinduction; Oligomerization; Protein refolding; VEGI

Indexed keywords

RECOMBINANT PROTEIN; RECOMBINANT VASCULAR ENDOTHELIAL GROWTH INHIBITOR 192; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL GROWTH INHIBITOR;

ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; APOPTOSIS; ARTICLE; CELL GROWTH; CHICKEN; CHORIOALLANTOIS; CONTROLLED STUDY; DRUG SOLUBILITY; ENDOTHELIUM CELL; GENE EXPRESSION SYSTEM; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STRUCTURE;

ANGIOGENESIS INHIBITORS; ANIMALS; CELL CULTURE TECHNIQUES; CHICK EMBRYO; CHORIOALLANTOIC MEMBRANE; CHROMATOGRAPHY, AFFINITY; HUMANS; NEOVASCULARIZATION, PHYSIOLOGIC; RECOMBINANT PROTEINS; TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 15;

EID: 77249162233     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.323     Document Type: Article

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