Getting to the heart of the matter: CCN2 plays a role in cardiomyocyte hypertrophy

Journal of Cell Communication and Signaling

Volumn 4, Issue 1, 2010, Pages 73-74

  Leask, Andrew ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Cardiac hypertrophy; CCN2; Connective tissue growth factor; Diabetes; TrkA

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; FATTY ACID; GLUCOSE; MESSENGER RNA; PROTEIN TYROSINE KINASE A;

APOPTOSIS; HEART HYPERTROPHY; HEART MUSCLE CELL; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SHORT SURVEY;

RATTUS;

EID: 77249141493     PISSN: 18739601     EISSN: 1873961X     Source Type: Journal    
DOI: 10.1007/s12079-009-0061-7     Document Type: Short Survey

References (8)

1. IE Blom R Goldschmeding A Leask 2002 Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy? Matrix Biol 21 6 473 82 10.1016/S0945-053X(02)00055-0 1:CAS:528:DC%2BD38XotVCntbo%3D 12392758 (Pubitemid 35248272)
2. D Feuvray A Darmellah 2008 Diabetes-related metabolic perturbations in cardiac myocyte Diabetes Metab 34 Suppl 1 S3 9 10.1016/S1262-3636(08)70096-X 1:CAS:528:DC%2BD1cXkslOlt7g%3D 18358420
3. AA Karnik AV Fields RP Shannon 2007 Diabetic cardiomyopathy Curr Hypertens Rep 9 6 467 73 10.1007/s11906-007-0086-3 18367010
4. A Leask DJ Abraham 2006 All in the CCN family: essential matricellular signaling modulators emerge from the bunker J Cell Sci 119 Pt 23 4803 10 10.1242/jcs.03270 1:CAS:528:DC%2BD2sXivFejsw%3D%3D 17130294 (Pubitemid 46017793)
5. Mason RM (2009) Connective tissue growth factor(CCN2), a pathogenic factor in diabetic nephropathy. What does it do? How does it do it? J Cell Commun Signal, Feb 14
6. V Paradis G Perlemuter F Bonvoust D Dargere B Parfait M Vidaud M Conti S Huet N Ba C Buffet P Bedossa 2001 High glucose and hyperinsulinemia stimulate connective tissue growth factor expression: a potential mechanism involved in progression to fibrosis in nonalcoholic steatohepatitis Hepatology 34 4 Pt 1 738 44 10.1053/jhep.2001.28055 1:CAS:528:DC%2BD3MXns1Kisro%3D 11584370 (Pubitemid 32927998)
7. NA Wahab BS Weston RM Mason 2005 Connective tissue growth factor CCN2 interacts with and activates the tyrosine kinase receptor TrkA J Am Soc Nephrol 16 2 340 51 10.1681/ASN.2003100905 1:CAS:528:DC%2BD2MXhvVCksL4%3D 15601748 (Pubitemid 41725129)
8. Wang XY, McLennan SV, Allen T, Tsoutsman T, Semsarian C, Twigg SM (2009) Adverse effects of high glucose and free fatty acid on cardiomyocytes are mediated by connective tissue growth factor. Am J Physiol Cell Physiol, Jul 22. [Epubahead of print]