Blood vessel density in de novo formed adipose tissue is decreased upon overexpression of TIMP-1

Obesity

Volumn 18, Issue 3, 2010, Pages 638-640

  Scroyen, Ilse ^a   Jacobs, Frank ^a   Cosemans, Leentje ^a   De Geest, Bart ^a   Lijnen, Henri R ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

MATRIX METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ADIPOCYTE; ADIPOGENESIS; ADIPOSE TISSUE; ANIMAL; ARTICLE; BAGG ALBINO MOUSE; BLOOD VESSEL; CELL STRAIN 3T3; DRUG ANTAGONISM; FAT INTAKE; HUMAN; MALE; METABOLISM; MOUSE; NUDE MOUSE; OBESITY; ORGAN SIZE; PATHOLOGY; VASCULARIZATION;

3T3 CELLS; ADIPOCYTES; ADIPOGENESIS; ADIPOSE TISSUE; ANIMALS; BLOOD VESSELS; DIETARY FATS; HUMANS; MALE; MATRIX METALLOPROTEINASES; MICE; MICE, INBRED BALB C; MICE, NUDE; OBESITY; ORGAN SIZE; TISSUE INHIBITOR OF METALLOPROTEINASE-1;

ADENOVIRIDAE; MUS; MUS MUSCULUS;

EID: 77249133556     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1038/oby.2009.279     Document Type: Article

References (15)

1. Crandall DL, Hausman GJ, Kral JG. A review of the microcirculation of adipose tissue: anatomic, metabolic, and angiogenic perspectives. Microcirculation 1997;4:211-232.
2. Christiaens V, Scroyen I, Lijnen HR. Role of proteolysis in development of murine adipose tissue. Thromb Haemost 2008;99:290-294.
3. Lijnen HR, Maquoi E, Holvoet P et al. Adipose tissue expression of gelatinases in mouse models of obesity. Thromb Haemost 2001;85:1111-1116.
4. Bouloumié A, Sengenès C, Portolan G, Galitzky J, Lafontan M. Adipocyte produces matrix metalloproteinases 2 and 9: involvement in adipose differentiation. Diabetes 2001;50:2080-2086.
5. Maquoi E, Demeulemeester D, Vörös G, Collen D, Lijnen HR. Enhanced nutritionally induced adipose tissue development in mice with stromelysin-1 gene inactivation. Thromb Haemost 2003;89:696-704.
6. Van Hul M, Lijnen HR. A functional role of gelatinase A in the development of nutritionally induced obesity in mice. J Thromb Haemost 2008;6:1198-1206.
7. Demeulemeester D, Collen D, Lijnen HR. Effect of matrix metalloproteinase inhibition on adipose tissue development. Biochem Biophys Res Commun 2005;329:105-110.
8. Lijnen HR, Maquoi E, Hansen LB et al. Matrix metalloproteinase inhibition impairs adipose tissue development in mice. Arterioscler Thromb Vasc Biol 2002;22:374-379.
9. Maquoi E, Munaut C, Colige A, Collen D, Lijnen HR. Modulation of adipose tissue expression of murine matrix metalloproteinases and their tissue inhibitors with obesity. Diabetes 2002;51:1093-1101.
10. Nagase H, Visse R, Murphy G. Structure and function of matrix metalloproteinases and TIMPs. Cardiovasc Res 2006;69:562-573.
11. Lijnen HR, Demeulemeester D, Van Hoef B, Collen D, Maquoi E. Deficiency of tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) impairs nutritionally induced obesity in mice. Thromb Haemost 2003;89:249-255.
12. Demeulemeester D, Scroyen I, Voros G et al. Overexpression of tissue inhibitor of matrix metalloproteinases-1 (TIMP-1) in mice does not affect adipogenesis or adipose tissue development. Thromb Haemost 2006;95:1019-1024.
13. Scroyen I, Jacobs F, Cosemans L, De Geest B, Lijnen HR. Effect of plasminogen activator inhibitor-1 on adipogenesis in vivo. Thromb Haemost 2009;101:388-393.
14. Green H, Kehinde O. Spontaneous heritable changes leading to increased adipose conversion in 3T3 cells. Cell 1976;7:105-113.
15. Whittaker P, Kloner RA, Boughner DR, Pickering JG. Quantitative assessment of myocardial collagen with picrosirius red staining and circularly polarized light. Basic Res Cardiol 1994;89:397-410.