Crystal Structure of Escherichia coli Enterobactin-specific Isochorismate Synthase (EntC) Bound to its Reaction Product Isochorismate: Implications for the Enzyme Mechanism and Differential Activity of Chorismate-utilizing Enzymes

Journal of Molecular Biology

Volumn 397, Issue 1, 2010, Pages 290-300

  Sridharan, Sudharsan ^a   Howard, Nigel ^a   Kerbarh, Olivier ^a   Błaszczyk, Michał ^a   Abell, Chris ^a   Blundell, Tom L ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

chorismate isochorismate; chorismate utilizing enzymes; EntC; enterobactin; siderophores

Indexed keywords

BACTERIAL ENZYME; CHORISMIC ACID; ENTEROCHELIN; ISOCHORISMATE SYNTHETASE; LYASE; PYRUVATE LYASE; SALICYLIC ACID; SYNTHETASE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; BIOTRANSFORMATION; CATALYSIS; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ESCHERICHIA COLI; HYDROGEN BOND; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; RESIDUE ANALYSIS; STRUCTURE ANALYSIS;

ESCHERICHIA COLI;

EID: 77249104442     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2010.01.019     Document Type: Article

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